{ "schemaVersion": "1.0.0", "project": "Type1Cure.com", "generatedAt": "2026-10-20T01:17:02.002Z", "sourceFeedGeneratedAt": "2026-10-20T01:17:02.002Z", "postCount": 140, "posts": [ { "id": "blog:2026-10-20:research-watch", "slug": "2026-10-20-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-20T08:00:00.000Z", "updatedAt": "2026-10-20T01:17:02.002Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-41993274.webp", "alt": "white microscope on top of black table", "credit": "Ousa Chea (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/white-microscope-on-top-of-black-table-gKUC4TMhOiY", "__contentHash": "b8c9e03da365ca2a7ff7bb2fc14c7cc22965bbfe7ae6d4bd6555e883e1a54a6d", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42878112", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China.", "url": "https://pubmed.ncbi.nlm.nih.gov/42878112/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-20" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China. — Journal of medical economics. Authors: Liu W, Ji L, Chen Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42878112/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-19:daily-type-1-diabetes-briefing", "slug": "2026-10-19-daily-type-1-diabetes-briefing", "title": "October 19, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-19T08:00:00.000Z", "updatedAt": "2026-10-19T23:17:01.428Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42393557.webp", "alt": "laboratory", "credit": "Openverse contributor (Openverse / CC0 1.0)", "license": "Openverse CC0 1.0", "sourceUrl": "https://svgsilh.com/ff5722/image/2025786.html", "__contentHash": "a5c98687c0f697d848c6973e7e6d27edd497bcc34681cee413d1fe9bb4d6ab54", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:222528", "clinicaltrials:NCT04011020", "clinicaltrials:NCT07831798", "openfda-device-recall:221918", "clinicaltrials:NCT05153070", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04011020", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-05" }, { "title": "VV-14300 for the Treatment of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07831798", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05153070", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-09" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 19, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes — RECRUITING, PHASE3. Interventions: Stem Cell Educator therapy. Locations: Paramus, New Jersey, United States | Paramus, New Jersey, United States. Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease that cause...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04011020" }, { "text": "VV-14300 for the Treatment of Type 1 Diabetes — RECRUITING, PHASE1, PHASE2. Interventions: VV-14300. Locations: Toronto, Canada | Christchurch, New Zealand. This study is testing VV-14300 in adults with long-standing type 1 diabetes (T1D) whose blood sugar is not wel...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07831798" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Cyclosporin, ILT101, Placebo. Locations: Paris, France. Type 1 diabetes (T1D) is caused by the destruction of insulin-producing cells by effector T cells (Teffs), due to a deficiency o...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05153070" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 19, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-19:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-19-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-19T08:00:00.000Z", "updatedAt": "2026-10-19T23:17:01.428Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42445886.webp", "alt": "Doctor nurse patient clinic FSA", "credit": "libraryofcongress (Openverse / CC0 1.0)", "license": "Openverse CC0 1.0", "sourceUrl": "https://www.rawpixel.com/image/12149585/image-person-art-book", "__contentHash": "c0f6a09a389ba2645aa6b0ce1aa8ef769299d41d1c38c68be7fe8254ee6c34b1", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT04011020", "clinicaltrials:NCT07831798", "clinicaltrials:NCT05153070", "clinicaltrials:NCT07212530", "clinicaltrials:NCT02000687", "clinicaltrials:NCT01630850", "clinicaltrials:NCT07193446", "clinicaltrials:NCT07144696", "clinicaltrials:NCT06951074", "clinicaltrials:NCT03316261" ], "sources": [ { "title": "Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04011020", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-05" }, { "title": "VV-14300 for the Treatment of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07831798", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-05" }, { "title": "Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05153070", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-09" }, { "title": "EmoTIChealth: Promoting Adolescent Health Through a Serious Game.", "url": "https://clinicaltrials.gov/study/NCT07212530", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-13" }, { "title": "Long Term Surveillance of Islet Transplant Recipients Following Complete Graft Loss", "url": "https://clinicaltrials.gov/study/NCT02000687", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-23" }, { "title": "Islet Transplantation in Patients With \"Brittle\" Type I Diabetes", "url": "https://clinicaltrials.gov/study/NCT01630850", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-09" }, { "title": "Optimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Adults With Type 1 Diabetes: a Feasibility Study (D-stress Study)", "url": "https://clinicaltrials.gov/study/NCT07193446", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-04" }, { "title": "Study on the Improvement of Metabolic Indicators in Type 1 Diabetes Patients", "url": "https://clinicaltrials.gov/study/NCT07144696", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-04" }, { "title": "Insulin Producing Stem Cell Transplantation Clinical Trial in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06951074", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-04-30" }, { "title": "Freder1k-Study - Testing Infants for Type 1 Diabetes Risk", "url": "https://clinicaltrials.gov/study/NCT03316261", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-17" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Clinical Application of Stem Cell Educator Therapy in Type 1 Diabetes — RECRUITING, PHASE3. Interventions: Stem Cell Educator therapy. Locations: Paramus, New Jersey, United States | Paramus, New Jersey, United States. Type 1 diabetes (T1D) is a T cell-mediated autoimmune disease that cause...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04011020" }, { "text": "VV-14300 for the Treatment of Type 1 Diabetes — RECRUITING, PHASE1, PHASE2. Interventions: VV-14300. Locations: Toronto, Canada | Christchurch, New Zealand. This study is testing VV-14300 in adults with long-standing type 1 diabetes (T1D) whose blood sugar is not wel...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07831798" }, { "text": "Ciclosporin Followed by Low-dose IL-2 in Patients With Recently Diagnosed Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Cyclosporin, ILT101, Placebo. Locations: Paris, France. Type 1 diabetes (T1D) is caused by the destruction of insulin-producing cells by effector T cells (Teffs), due to a deficiency o...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05153070" }, { "text": "EmoTIChealth: Promoting Adolescent Health Through a Serious Game. — RECRUITING, NA. Interventions: EmoTIChealth. Locations: Valencia, Valencia, Spain. The intervention program targets adolescents between 12 and 16 years of age. The intervention program is designed for adolescents during...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07212530" }, { "text": "Long Term Surveillance of Islet Transplant Recipients Following Complete Graft Loss — RECRUITING. Locations: Miami, Florida, United States. This is a single-center, prospective, open label study in islet transplant recipients following islet graft loss.", "sourceUrl": "https://clinicaltrials.gov/study/NCT02000687" }, { "text": "Islet Transplantation in Patients With \"Brittle\" Type I Diabetes — RECRUITING, NA. Interventions: Allogenic islet cells (human, U. Chicago), Intraportal infusion of islet cells. Locations: Chicago, Illinois, United States. The purpose of this study is to learn about the safety of islet...", "sourceUrl": "https://clinicaltrials.gov/study/NCT01630850" }, { "text": "Optimising the Delivery of Diabetes Distress Informed Care for Its Prevention, Detection, and Management in Adults With Type 1 Diabetes: a Feasibility Study (D-stress Study) — RECRUITING, NA. Interventions: D-stress study: The detection, prevention and management of diabetes distress for adults living with type 1 diabetes.. Locations: Bath, United Kingdom | Leicester, United Kingdom | London,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07193446" }, { "text": "Study on the Improvement of Metabolic Indicators in Type 1 Diabetes Patients — RECRUITING, NA. Interventions: structured education and regular follow-up. Locations: Beijing, China. In this study, type 1 diabetes patients from the outpatient department of Peking University First Hospital were selec...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07144696" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-19:research-watch", "slug": "2026-10-19-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-19T08:00:00.000Z", "updatedAt": "2026-10-19T23:17:01.428Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42812195.webp", "alt": "Medical laboratory in Galata", "credit": "Андрей Романенко (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=136508609", "__contentHash": "0db8de15f149453c1b8905a8b14aa1fb0da1011786e6e5edf1065aa542e4c366", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42878112", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China.", "url": "https://pubmed.ncbi.nlm.nih.gov/42878112/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-19" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China. — Journal of medical economics. Authors: Liu W, Ji L, Chen Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42878112/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-18:research-watch", "slug": "2026-10-18-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-18T08:00:00.000Z", "updatedAt": "2026-10-18T23:17:01.773Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42760519.webp", "alt": "Medical Laboratory personnel in Nigeria", "credit": "Beendy234 (Openverse / BY 4.0)", "license": "Openverse BY 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=162679684", "__contentHash": "abc31135ea3ac049ffe0613a0e1a8e4f1b3a1495a6fb300792b72eaddbe0f4c5", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42878112", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China.", "url": "https://pubmed.ncbi.nlm.nih.gov/42878112/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-18" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China. — Journal of medical economics. Authors: Liu W, Ji L, Chen Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42878112/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-17:research-watch", "slug": "2026-10-17-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-17T08:00:00.000Z", "updatedAt": "2026-10-17T23:17:01.330Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42417811.webp", "alt": "Ross Marklein, Ph.D., a post-doctoral research fellow at FDA, examines images of stem cells in an FDA laboratory on the National Institutes of Health campus in ", "credit": "The U.S. Food and Drug Administration (Wikimedia Commons)", "license": "Public domain", "sourceUrl": "https://commons.wikimedia.org/wiki/File:Stem_Cell_Research.jpg", "__contentHash": "b79227875d8bfc009c599763a45be559e98c5889195595927ea176218f4f0093", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42878112", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China.", "url": "https://pubmed.ncbi.nlm.nih.gov/42878112/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-17" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China. — Journal of medical economics. Authors: Liu W, Ji L, Chen Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42878112/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-16:daily-type-1-diabetes-briefing", "slug": "2026-10-16-daily-type-1-diabetes-briefing", "title": "October 16, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-16T08:00:00.000Z", "updatedAt": "2026-10-16T23:17:01.605Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42430041.webp", "alt": "Flat lay of diabetes awareness concept with glucose meter, insulin syringes, sugar cubes, and donut.", "credit": "Nataliya Vaitkevich (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/blood-sugar-meter-and-sweets-on-the-blue-background-6942013/", "__contentHash": "5716f230110b5f62b20f485fe1bfba46bf244e424cf27f028c1e0508cb7a4129", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:222528", "openfda-device-recall:221918", "clinicaltrials:NCT07699380", "clinicaltrials:NCT07814508", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "clinicaltrials:NCT06688331", "openfda-device-recall:221053" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)", "url": "https://clinicaltrials.gov/study/NCT07699380", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-15" }, { "title": "Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App", "url": "https://clinicaltrials.gov/study/NCT07814508", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody", "url": "https://clinicaltrials.gov/study/NCT06688331", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 16, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D) — RECRUITING, PHASE2. Interventions: AMX0035, Placebo. Locations: Seattle, Washington, United States | Amsterdam, Netherlands. The study is a randomized, double-blind, parallel-group clinical trial to examine the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07699380" }, { "text": "Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App — RECRUITING, NA. Interventions: SmartGuide CGM without Predict App, SmartGuide CGM with Predict App. Locations: Bad Mergentheim, Baden-Wurttemberg, Germany. The goal of this controlled pre-post-trial is to test the Accu-...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07814508" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 16, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-16:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-16-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-16T08:00:00.000Z", "updatedAt": "2026-10-16T23:17:01.605Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42411999.webp", "alt": "Heba Degheidy, M.D., Ph.D., a visiting research associate at FDA, works with stem cell samples in an FDA laboratory on the National Institutes of Health campus ", "credit": "The U.S. Food and Drug Administration (Wikimedia Commons)", "license": "Public domain", "sourceUrl": "https://commons.wikimedia.org/wiki/File:Stem_Cell_Research_(0456)_(13978787731).jpg", "__contentHash": "a55ac993cab9c6f7bfb228a1aabb2c9d514d94406d8c4265fff9f4ad971d49c1", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07699380", "clinicaltrials:NCT07814508", "clinicaltrials:NCT06688331", "clinicaltrials:NCT01999374", "clinicaltrials:NCT07455994", "clinicaltrials:NCT06915831", "clinicaltrials:NCT07242664", "clinicaltrials:NCT06708780" ], "sources": [ { "title": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)", "url": "https://clinicaltrials.gov/study/NCT07699380", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-15" }, { "title": "Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App", "url": "https://clinicaltrials.gov/study/NCT07814508", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody", "url": "https://clinicaltrials.gov/study/NCT06688331", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" }, { "title": "Long Term Follow up of Recipients of Functional Islet Allografts", "url": "https://clinicaltrials.gov/study/NCT01999374", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-23" }, { "title": "Dysautonomia in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07455994", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-06" }, { "title": "Type 1 Diabetes and Obstructive Sleep Apnea", "url": "https://clinicaltrials.gov/study/NCT06915831", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-20" }, { "title": "Clamp Study to Estimate the Relative Potency of GZR33 Versus Insulin Degludec at Steady State", "url": "https://clinicaltrials.gov/study/NCT07242664", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-11-21" }, { "title": "Immunotherapy with Autologous Tregs in T1DM", "url": "https://clinicaltrials.gov/study/NCT06708780", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-11-27" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D) — RECRUITING, PHASE2. Interventions: AMX0035, Placebo. Locations: Seattle, Washington, United States | Amsterdam, Netherlands. The study is a randomized, double-blind, parallel-group clinical trial to examine the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07699380" }, { "text": "Changes in Person-reported Outcomes and Behavior Using the Accu-Chek SmartGuide CGM and Predict App — RECRUITING, NA. Interventions: SmartGuide CGM without Predict App, SmartGuide CGM with Predict App. Locations: Bad Mergentheim, Baden-Wurttemberg, Germany. The goal of this controlled pre-post-trial is to test the Accu-...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07814508" }, { "text": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody — RECRUITING, PHASE2. Interventions: ex vivo expanded CD4+CD25+CD127- regulatory T cells (Tregs), Anti-CD20 (rituximab), Placebo. Locations: Bialystok, Poland | Gdansk, Poland | Katowice, Poland. The main purpose of the s...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06688331" }, { "text": "Long Term Follow up of Recipients of Functional Islet Allografts — RECRUITING. Locations: Miami, Florida, United States. Since its inception, the Diabetes Research Institute (DRI) has made significant contributions to the field of diabetes, pioneering many of the techniques used in dia...", "sourceUrl": "https://clinicaltrials.gov/study/NCT01999374" }, { "text": "Dysautonomia in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Neurocoach® and Sudoscan®. Locations: Saint-Etienne, France. Some physiological factors, such as physical activity, or pathological factors, such as sepsis or diabetes, are known to modula...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07455994" }, { "text": "Type 1 Diabetes and Obstructive Sleep Apnea — RECRUITING, NA. Interventions: Continuous positive airway pressure (CPAP). Locations: Chicago, Illinois, United States. The purpose of the study is to investigate the role of sleep apnea in glycemic dysregulation in adu...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06915831" }, { "text": "Clamp Study to Estimate the Relative Potency of GZR33 Versus Insulin Degludec at Steady State — RECRUITING, PHASE1. Interventions: GZR-33. Locations: Neuss, Germany | Neuss, Germany. This trial intends to investigate the pharmacodynamics, pharmacokinetics, safety, and tolerability of insulin GZR33 (hereafter refer...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07242664" }, { "text": "Immunotherapy with Autologous Tregs in T1DM — RECRUITING, PHASE1. Interventions: Ex vivo Expanded Human Autologous Regulatory T Cells, Routine Care. Locations: Nanjing, Jiangsu, China. Type 1 diabetes (T1D) is an autoimmune disease characterized by a progressive im...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06708780" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-16:research-watch", "slug": "2026-10-16-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-16T08:00:00.000Z", "updatedAt": "2026-10-16T23:17:01.605Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-8eef32f31df76a5f.webp", "alt": "Induced Pluripotent Stem Cells of Huntington's Disease", "credit": "Ningzhe Zhang, Mahru C. An, Daniel Montoro, and Lisa M. Ellerby (Openverse / BY 3.0)", "license": "Openverse BY 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=39561271", "__contentHash": "0c31aab5b04b9a89665814f32066193fd71e57935de4c123f05332064ff236f9", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42878112", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China.", "url": "https://pubmed.ncbi.nlm.nih.gov/42878112/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-16" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China. — Journal of medical economics. Authors: Liu W, Ji L, Chen Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42878112/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-15:daily-type-1-diabetes-briefing", "slug": "2026-10-15-daily-type-1-diabetes-briefing", "title": "October 15, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-15T08:00:00.000Z", "updatedAt": "2026-10-15T23:17:01.237Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-39d82c6da20d41a2.webp", "alt": "Woman holding an insulin pen, showcasing healthcare and diabetes management in a modern setting.", "credit": "Pavel Danilyuk (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-woman-holding-an-insulin-injection-pen-7653692/", "__contentHash": "e93061468c24fc0753f0160e4be34c2c78f247ce97e213c43e6969bef22d22a3", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:222528", "openfda-device-recall:221918", "clinicaltrials:NCT07830082", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Drawing and Writing Activities in Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07830082", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-21" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 15, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Drawing and Writing Activities in Adolescents With Type 1 Diabetes — RECRUITING, NA. Interventions: Drawing and Writing Intervention. Locations: Ankara, Ankara, Turkey (Türkiye). This randomized controlled trial aims to evaluate the effects of drawing and writing activities on anxiety an...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07830082" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 15, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-15:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-15-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-15T08:00:00.000Z", "updatedAt": "2026-10-15T23:17:01.237Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-dd2a4917c5f6b71d.webp", "alt": "Single Photon Emission Computed Tomography (SPECT) with circular containment tube at biosafety level 4 (BSL-4) laboratory of the NIAID Integrated Research Facil", "credit": "National Institute of Allergy and Infectious Diseases (Wikimedia Commons)", "license": "Public domain", "sourceUrl": "https://commons.wikimedia.org/wiki/File:NIAID_Integrated_Research_Facility_-_SPECT.jpg", "__contentHash": "cb7e6ade5c339511634cfbd738c2f768cd21ae10e7a41fa5d1bbb358ebddb1d2", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07830082", "clinicaltrials:NCT06748963", "clinicaltrials:NCT07468474", "clinicaltrials:NCT07159282", "clinicaltrials:NCT07260110", "clinicaltrials:NCT06665815", "clinicaltrials:NCT05713448", "clinicaltrials:NCT05546138", "clinicaltrials:NCT05692778" ], "sources": [ { "title": "Drawing and Writing Activities in Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07830082", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-21" }, { "title": "Fasted Exercise Training in Type 1 Diabetes (FED-T1D)", "url": "https://clinicaltrials.gov/study/NCT06748963", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-08" }, { "title": "Establishment of Screening Pathway for High-Risk Population of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07468474", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-12" }, { "title": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers", "url": "https://clinicaltrials.gov/study/NCT07159282", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-11" }, { "title": "A Longitudinal, Observational Study Comparing Real-World Experiences of Teplizumab-Treated and Untreated Participants With Stage 2 Type 1 Diabetes in the United States", "url": "https://clinicaltrials.gov/study/NCT07260110", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-03" }, { "title": "A National Screening Program for Islet Autoantibodies Among First-degree Relatives of T1D Patients", "url": "https://clinicaltrials.gov/study/NCT06665815", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-20" }, { "title": "Prevalence of Overweight and Obesity in Adult Patients Suffering From Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05713448", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-07-01" }, { "title": "Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy", "url": "https://clinicaltrials.gov/study/NCT05546138", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-06-28" }, { "title": "Optimized Care of People With Diabetes and Foot Complication in Primary Care", "url": "https://clinicaltrials.gov/study/NCT05692778", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-04-17" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Drawing and Writing Activities in Adolescents With Type 1 Diabetes — RECRUITING, NA. Interventions: Drawing and Writing Intervention. Locations: Ankara, Ankara, Turkey (Türkiye). This randomized controlled trial aims to evaluate the effects of drawing and writing activities on anxiety an...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07830082" }, { "text": "Fasted Exercise Training in Type 1 Diabetes (FED-T1D) — RECRUITING, NA. Interventions: Fasted Exercise, Postprandial Exercise. Locations: Edmonton, Alberta, Canada. This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to simila...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06748963" }, { "text": "Establishment of Screening Pathway for High-Risk Population of Type 1 Diabetes — RECRUITING. Interventions: Gene polymorphic detection. Locations: Beijing, Beijing Municipality, China. This study aims to establish a system for identifying and screening high-risk individuals for type 1 diabetes (T1D)...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07468474" }, { "text": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers — RECRUITING, PHASE4. Interventions: XWRAP. Locations: Hollywood, Florida, United States. A multicenter, prospective, controlled clinical trial evaluating the efficacy of a single layer placental-based allograft and stand...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07159282" }, { "text": "A Longitudinal, Observational Study Comparing Real-World Experiences of Teplizumab-Treated and Untreated Participants With Stage 2 Type 1 Diabetes in the United States — RECRUITING. Interventions: Teplizumab. Locations: San Francisco, California, United States. This study is an observational, longitudinal, non-interventional real-world study in the United States. The study is meant to d...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07260110" }, { "text": "A National Screening Program for Islet Autoantibodies Among First-degree Relatives of T1D Patients — RECRUITING. Locations: Petah Tikva, Israel. A national Screening program for the presence of Islet Autoantibodies (IA) in relatives of people with type 1 diabetes (PWT1D) aiming at identifying people with pre-clinical (...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06665815" }, { "text": "Prevalence of Overweight and Obesity in Adult Patients Suffering From Type 1 Diabetes — RECRUITING. Interventions: No intervention. Locations: Leuven, Belgium. A registry of individuals with type 1 diabetes that visited the Department of Endocrinology of the University Hospitals of Leuven is established. T...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05713448" }, { "text": "Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy — RECRUITING. Interventions: Skin biopsies with quantification of intra-epidermal nerve fibre density, Perception Threshold Tracking, Thermal perception thresholds. Locations: Aalborg, Denmark. Predicting early onset neur...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05546138" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-15:research-watch", "slug": "2026-10-15-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-15T08:00:00.000Z", "updatedAt": "2026-10-15T23:17:01.237Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-86f857eb1aad7e3b.webp", "alt": "Magnetic Resonance Imaging (MRI) with circular containment tube at biosafety level 4 (BSL-4) laboratory of the NIAID Integrated Research Facility (IRF) in Frede", "credit": "National Institute of Allergy and Infectious Diseases (Wikimedia Commons)", "license": "Public domain", "sourceUrl": "https://commons.wikimedia.org/wiki/File:NIAID_Integrated_Research_Facility_-_MRI.jpg", "__contentHash": "9dd11ef3b03a695f845c18ae0d0b1bea40991b22c17170b0c9f586a8f7d5e9d9", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42878112", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China.", "url": "https://pubmed.ncbi.nlm.nih.gov/42878112/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-15" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Treatment patterns, healthcare utilization, and healthcare costs in patients with newly diagnosed type 1 diabetes: a retrospective real-world study in Tianjin, China. — Journal of medical economics. Authors: Liu W, Ji L, Chen Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42878112/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-14:daily-type-1-diabetes-briefing", "slug": "2026-10-14-daily-type-1-diabetes-briefing", "title": "October 14, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-14T08:00:00.000Z", "updatedAt": "2026-10-14T23:17:01.946Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42456938.webp", "alt": "Diabetic Type 1 adult man with insulin pump and CGM sensor", "credit": "Medtd1 (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=124667464", "__contentHash": "8a0b6fd535abfa48fa19e020089ac0424bd645ec6966ab1d257d0824eab7acd8", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07423637", "clinicaltrials:NCT07862101", "openfda-device-recall:222528", "openfda-device-recall:221918", "clinicaltrials:NCT06273631", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "The Impact of Early Automated Insulin Delivery (AID) Therapy on Diabetes Control and Comorbidities, and Cost-effectiveness of AID Treatment", "url": "https://clinicaltrials.gov/study/NCT07423637", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-14" }, { "title": "Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients", "url": "https://clinicaltrials.gov/study/NCT07862101", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-07" }, { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06273631", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-10" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 14, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "The Impact of Early Automated Insulin Delivery (AID) Therapy on Diabetes Control and Comorbidities, and Cost-effectiveness of AID Treatment — RECRUITING, NA. Interventions: Omnipod 5, Multiple daily injections of insulin. Locations: Espoo, Finland | Helsinki, Finland. The purpose of this study is to investigate the effect of early initiated automated insulin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07423637" }, { "text": "Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients — RECRUITING. Locations: Bari, BA, Italy. Celiac disease (CD) and type 1 diabetes mellitus (T1D) are chronic autoimmune disorders that frequently co-occur, largely due to shared genetic susceptibility, particularly HLA-DQ...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07862101" }, { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: diverse carbohydrate diet, moderate carbohydrate diet. Locations: Nanjing, Jiangsu, China. This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06273631" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 14, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-14:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-14-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-14T08:00:00.000Z", "updatedAt": "2026-10-14T23:17:01.946Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-signal-9f84e556d5be20d7.webp", "alt": "Doctor in white coat checking patient chart in hospital room with medical equipment.", "credit": "RDNE Stock project (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-physician-in-white-coat-checking-up-on-his-patient-6129246/", "__contentHash": "6cd670280c9a83de2bbd8a678e1aeb6f3475ce279fadc509ee1923601059ab82", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07423637", "clinicaltrials:NCT07862101", "clinicaltrials:NCT06273631", "clinicaltrials:NCT07038473", "clinicaltrials:NCT04334707", "clinicaltrials:NCT06670625", "clinicaltrials:NCT06236607", "clinicaltrials:NCT06676657", "clinicaltrials:NCT05957055" ], "sources": [ { "title": "The Impact of Early Automated Insulin Delivery (AID) Therapy on Diabetes Control and Comorbidities, and Cost-effectiveness of AID Treatment", "url": "https://clinicaltrials.gov/study/NCT07423637", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-14" }, { "title": "Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients", "url": "https://clinicaltrials.gov/study/NCT07862101", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-10-07" }, { "title": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06273631", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-10" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Kidney Precision Medicine Project", "url": "https://clinicaltrials.gov/study/NCT04334707", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-14" }, { "title": "Intensive Dietary and Activity Counselling (IDAC)", "url": "https://clinicaltrials.gov/study/NCT06670625", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-13" }, { "title": "Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06236607", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-01" }, { "title": "Closed Loop Context Aware AID", "url": "https://clinicaltrials.gov/study/NCT06676657", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-04-11" }, { "title": "Lisdexamphetamine Vs Methylphenidate for Pediatric Patients with ADHD and Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05957055", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-11-29" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "The Impact of Early Automated Insulin Delivery (AID) Therapy on Diabetes Control and Comorbidities, and Cost-effectiveness of AID Treatment — RECRUITING, NA. Interventions: Omnipod 5, Multiple daily injections of insulin. Locations: Espoo, Finland | Helsinki, Finland. The purpose of this study is to investigate the effect of early initiated automated insulin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07423637" }, { "text": "Strategy For Assessing The Risk Of Type 1 Diabetes In Pediatric Celiac Patients — RECRUITING. Locations: Bari, BA, Italy. Celiac disease (CD) and type 1 diabetes mellitus (T1D) are chronic autoimmune disorders that frequently co-occur, largely due to shared genetic susceptibility, particularly HLA-DQ...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07862101" }, { "text": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: diverse carbohydrate diet, moderate carbohydrate diet. Locations: Nanjing, Jiangsu, China. This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06273631" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Kidney Precision Medicine Project — RECRUITING. Interventions: Kidney Biopsy, MRI, Retina Scan. Locations: Tucson, Arizona, United States | New Haven, Connecticut, United States | Chicago, Illinois, United States. Acute kidney injury (AKI) and chronic kid...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04334707" }, { "text": "Intensive Dietary and Activity Counselling (IDAC) — RECRUITING, NA. Interventions: IDAC+. Locations: Malmö, Sweden. The aim of this intervention study is to investigate if a intensive dietary and physical activity counselling during the first two years of life in childre...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06670625" }, { "text": "Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes — RECRUITING, NA. Interventions: Device specific training, Study clinician/educator visit. Locations: Boston, Massachusetts, United States | The Bronx, New York, United States. Minoritized individuals with type 1 diabetes...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06236607" }, { "text": "Closed Loop Context Aware AID — RECRUITING, NA. Interventions: iPancreas automated insulin delivery system. Locations: Portland, Oregon, United States. An artificial pancreas (AP) is a control system for automatic insulin delivery. The investigators h...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06676657" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-14:research-watch", "slug": "2026-10-14-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-14T08:00:00.000Z", "updatedAt": "2026-10-14T23:17:01.946Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42702386.webp", "alt": "Laboratory technician working with a cell", "credit": "Centers for Disease Control and Prevention (Openverse / CC0 1.0)", "license": "Openverse CC0 1.0", "sourceUrl": "https://www.rawpixel.com/image/2282489/free-photo-image-laboratory-technician-medical", "__contentHash": "388b3332469d217382077e4289ddaba48f4059375110f4dabfcb722ab00411db", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-14" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-13:daily-type-1-diabetes-briefing", "slug": "2026-10-13-daily-type-1-diabetes-briefing", "title": "October 13, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-13T08:00:00.000Z", "updatedAt": "2026-10-13T23:17:01.401Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42460849.webp", "alt": "Symbolic image of diabetes prevention message with pineapple and insulin syringes.", "credit": "Nataliya Vaitkevich (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/letter-dices-over-a-cut-pineapple-fruit-6942072/", "__contentHash": "7a0d7a574ba0e67d28e114da7619f2bb8a9ac725ad00706f555f1c6dc2292d4a", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:222528", "openfda-device-recall:221918", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "clinicaltrials:NCT06880835", "openfda-device-recall:221053", "clinicaltrials:NCT06694558", "openfda-device-recall:220614" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery", "url": "https://clinicaltrials.gov/study/NCT06880835", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-16" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease", "url": "https://clinicaltrials.gov/study/NCT06694558", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 13, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery — RECRUITING, NA. Interventions: Control IQ + sleep or exercise activity with TI. Locations: Louisville, Kentucky, United States | Philadelphia, Pennsylvania, United States | Seattle, Washington, United States. This inves...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06880835" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 13, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-13:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-13-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-13T08:00:00.000Z", "updatedAt": "2026-10-13T23:17:01.401Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42424245.webp", "alt": "Healthcare professional checks temperature with digital thermometer during patient consultation in a medical office undefined", "credit": "Shixart1985 (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=191645344", "__contentHash": "9ee80cf5c34f1831fc21edeb984d800533c4ce9c25bcb8f9ed2d4c9bb052d32c", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06880835", "clinicaltrials:NCT06694558", "clinicaltrials:NCT06575842", "clinicaltrials:NCT07427134", "clinicaltrials:NCT06709755", "clinicaltrials:NCT07293715", "clinicaltrials:NCT07062887", "clinicaltrials:NCT06338553", "clinicaltrials:NCT06256614", "clinicaltrials:NCT06618027" ], "sources": [ { "title": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery", "url": "https://clinicaltrials.gov/study/NCT06880835", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-16" }, { "title": "Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease", "url": "https://clinicaltrials.gov/study/NCT06694558", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-08" }, { "title": "Accuracy of Continuous Glucose Monitors During the Perioperative Period in Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06575842", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-12" }, { "title": "Pediatric Insulin Plan Calculator for T1DM Management", "url": "https://clinicaltrials.gov/study/NCT07427134", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-09" }, { "title": "A Hybrid Effectiveness-implementation Trial to Reduce Diabetes Distress in Teenagers", "url": "https://clinicaltrials.gov/study/NCT06709755", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-29" }, { "title": "Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D)", "url": "https://clinicaltrials.gov/study/NCT07293715", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-29" }, { "title": "Digital Mindfulness for Young Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07062887", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-09" }, { "title": "GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab", "url": "https://clinicaltrials.gov/study/NCT06338553", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-18" }, { "title": "Washed Microbiota Transplantation for Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT06256614", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-10" }, { "title": "Pragmatic Clinic-Based Trial of a Mindfulness Based Intervention for Mood Concerns in Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06618027", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-08" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery — RECRUITING, NA. Interventions: Control IQ + sleep or exercise activity with TI. Locations: Louisville, Kentucky, United States | Philadelphia, Pennsylvania, United States | Seattle, Washington, United States. This inves...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06880835" }, { "text": "Monocytes in Subjects With Type 1 Diabetes and Chronic Kidney Disease — RECRUITING. Locations: Cleveland, Ohio, United States. This is a cross-sectional study in patients with Type 1 diabetes (TID) and chronic kidney disease (CKD) to test if time in range (TIR) affects the degree of hypergl...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06694558" }, { "text": "Accuracy of Continuous Glucose Monitors During the Perioperative Period in Youth With Type 1 Diabetes — RECRUITING. Locations: Aurora, Colorado, United States. This study is assessing the accuracy of continuous glucose monitors during surgical procedures requiring anesthesia.", "sourceUrl": "https://clinicaltrials.gov/study/NCT06575842" }, { "text": "Pediatric Insulin Plan Calculator for T1DM Management — RECRUITING, NA. Interventions: Flexible Digital Insulin Dose Calculator. Locations: Mosul, Iraq | Lahore, Pakistan. This is a multi-centre, prospective, randomized, open-label controlled trial designed to evaluate the e...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07427134" }, { "text": "A Hybrid Effectiveness-implementation Trial to Reduce Diabetes Distress in Teenagers — RECRUITING, NA. Interventions: Supporting Teen Problem Solving, Diabetes Education. Locations: Chicago, Illinois, United States. The investigators will assess both effectiveness (primary) and implementation (secondary)...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06709755" }, { "text": "Permissive Versus Strict Intrapartum Glucose Management in Type 1 Diabetes (PRISM-T1D) — RECRUITING, PHASE4. Interventions: Insulin, DEXCOM Continuous Glucose Monitor. Locations: Columbus, Ohio, United States. PRISM-TID is a single center non-inferiority randomized controlled trial of permissive intrapartum...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07293715" }, { "text": "Digital Mindfulness for Young Adults With Type 1 Diabetes — RECRUITING, NA. Interventions: Mindfulness app. Locations: New Haven, Connecticut, United States. The purpose of this research study is to test a mindfulness app called Calm Health among young adults with type 1 diabete...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07062887" }, { "text": "GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab — RECRUITING, EARLY_PHASE1. Interventions: Semaglutide (Rybelsus®), Placebo. Locations: Nashville, Tennessee, United States. The goal of this study is to determine how a drug class called glucagon-like peptide-1 receptor...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06338553" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-13:research-watch", "slug": "2026-10-13-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-13T08:00:00.000Z", "updatedAt": "2026-10-13T23:17:01.401Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-3b90810412adf3a0.webp", "alt": "Senior researcher working with a microscope in a laboratory setting, assisted by a colleague.", "credit": "https://kaboompics.com/ (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/woman-using-a-microscope-on-a-white-table-8539453/", "__contentHash": "85aa1bce522f0e4c255546c2256bc0771b2f50c9f0b7000c8a8669d7a4682f06", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-13" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-12:research-watch", "slug": "2026-10-12-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-12T08:00:00.000Z", "updatedAt": "2026-10-12T23:17:01.300Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-3cf7ddde8701b59c.webp", "alt": "Two female scientists conducting research with microscope in a laboratory setting.", "credit": "www.kaboompics.com (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/women-inside-a-laboratory-doing-research-and-analysis-8539649/", "__contentHash": "373e36994b9614ed16475ce4c944a0aaa0bba63c8e0e197025798fe99381cc92", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-12" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-11:daily-type-1-diabetes-briefing", "slug": "2026-10-11-daily-type-1-diabetes-briefing", "title": "October 11, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-11T08:00:00.000Z", "updatedAt": "2026-10-11T23:17:01.641Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42470111.webp", "alt": "Close-up of a glucometer reading 95 mg/dl with a lancing device, ideal for diabetes and healthcare imagery.", "credit": "Arunangshu Banerjee (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/blood-sugar-measurement-with-glucometer-and-lancing-device-33200678/", "__contentHash": "204588c766a41558cc59dbc3fb12d7a4400508abfc1d26056a2b40971f7a8458", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:222528", "openfda-device-recall:221918", "clinicaltrials:NCT07216391", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07409701", "clinicaltrials:NCT07579702", "openfda-device-recall:221103", "openfda-device-recall:221053" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG", "url": "https://clinicaltrials.gov/study/NCT07216391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-09" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Gamification Intervertion in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07409701", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System", "url": "https://clinicaltrials.gov/study/NCT07579702", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-03" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 11, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG — RECRUITING, PHASE2. Interventions: Antithymocyte Globulin (ATG), Teplizumab. Locations: Aurora, Colorado, United States | New Haven, Connecticut, United States | Gainesville, Florida, United States. This is a 2-arm, mul...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07216391" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Gamification Intervertion in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Gamification. Locations: Ankara, Yenimahalle, Turkey (Türkiye). Objective: This study aims to examine the effect of education provided through gamification methods on health literacy and q...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07409701" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 11, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-11:research-watch", "slug": "2026-10-11-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-11T08:00:00.000Z", "updatedAt": "2026-10-11T23:17:01.641Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-d629d3989184f1e7.webp", "alt": "A female scientist uses a microscope in a laboratory, focusing on research and analysis.", "credit": "Tima Miroshnichenko (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-woman-using-a-microscope-9574398/", "__contentHash": "3c7a445e437155d7912a15dcbf354c556955405036828a77f6d8750ed1385caf", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-11" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-10:research-watch", "slug": "2026-10-10-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-10T08:00:00.000Z", "updatedAt": "2026-10-10T23:17:01.829Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42450322.webp", "alt": "Artistic depiction of red blood cells on a white background, emphasizing medical concepts.", "credit": "Roger Brown (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/red-bloodcells-on-white-surface-5149400/", "__contentHash": "3c9b47dbaee552e9e796f2e5740c6f7fe81cd796265bf197019c7a408b051a20", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-10" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-09:daily-type-1-diabetes-briefing", "slug": "2026-10-09-daily-type-1-diabetes-briefing", "title": "October 9, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-09T08:00:00.000Z", "updatedAt": "2026-10-09T23:17:01.739Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42455340.webp", "alt": "Top view of lancets for blood glucose meter placed near glucometer and letter board with World Diabetes Day inscription", "credit": "Klaus Nielsen (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/composition-of-letter-board-placed-near-devices-for-diabetics-6303708/", "__contentHash": "8652026d8c1de456315fac5e96d9fb4144ccc97c15b385fb1eb9c6d9f41c77dc", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:222528", "openfda-device-recall:221918", "clinicaltrials:NCT07216391", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07409701", "clinicaltrials:NCT07579702", "openfda-device-recall:221103", "openfda-device-recall:221053" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG", "url": "https://clinicaltrials.gov/study/NCT07216391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-09" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Gamification Intervertion in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07409701", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System", "url": "https://clinicaltrials.gov/study/NCT07579702", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-03" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 9, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG — RECRUITING, PHASE2. Interventions: Antithymocyte Globulin (ATG), Teplizumab. Locations: Aurora, Colorado, United States | New Haven, Connecticut, United States | Gainesville, Florida, United States. This is a 2-arm, mul...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07216391" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Gamification Intervertion in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Gamification. Locations: Ankara, Yenimahalle, Turkey (Türkiye). Objective: This study aims to examine the effect of education provided through gamification methods on health literacy and q...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07409701" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 9, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-09:device-safety-watch", "slug": "2026-10-09-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-09T08:00:00.000Z", "updatedAt": "2026-10-09T23:17:01.739Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-signal-93474745c04bc5ed.webp", "alt": "Channon prototype insulin pump 1978-79", "credit": "Robert Channon (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=115739345", "__contentHash": "389412cea9fd69bfe5fcaa21845ff759f1de7a7bdcc8542bb553ec5fd74e9ea4", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:222528", "openfda-device-recall:221918", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-10-05" }, { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: Brand Name: MiniMed Flex Product Name: MiniMed Flex Insulin Pump Model/Catalog Numbers: MMT-8062; MMT-8072 Product Description: The MiniMed Flex pump is an alternate controller en... — Some MiniMed Flex insulin pumps were released with missing (i.e., devices with no result or abort test results are presumed to have failed) or failed verification test results in one or more of 9 functional tests. The u...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=222528" }, { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-10-09:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-09-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-09T08:00:00.000Z", "updatedAt": "2026-10-09T23:17:01.739Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42409045.webp", "alt": "Doctor in consultation with patient at a medical clinic, discussing treatment options.", "credit": "CDC (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/woman-having-a-check-up-3992806/", "__contentHash": "a9224b83398dd8208ac54484b812cf349e4079db6b378c38a9d6b57ec8b23b04", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07216391", "clinicaltrials:NCT07409701", "clinicaltrials:NCT07579702", "clinicaltrials:NCT07011147", "clinicaltrials:NCT06686329", "clinicaltrials:NCT06256614", "clinicaltrials:NCT02306005" ], "sources": [ { "title": "Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG", "url": "https://clinicaltrials.gov/study/NCT07216391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-09" }, { "title": "Gamification Intervertion in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07409701", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System", "url": "https://clinicaltrials.gov/study/NCT07579702", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-03" }, { "title": "Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery", "url": "https://clinicaltrials.gov/study/NCT07011147", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-11" }, { "title": "Physical Activity to Prevent and Treat Hyperglycemia From a Mistimed Bolus Insulin Dose", "url": "https://clinicaltrials.gov/study/NCT06686329", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-12" }, { "title": "Washed Microbiota Transplantation for Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT06256614", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-10" }, { "title": "Insulin Therapy and Lipoproteins' Profile in Type 1 Diabetes.", "url": "https://clinicaltrials.gov/study/NCT02306005", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-05" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Platform Trial to Delay Stage 3 Diabetes: Comparing Teplizumab With ATG — RECRUITING, PHASE2. Interventions: Antithymocyte Globulin (ATG), Teplizumab. Locations: Aurora, Colorado, United States | New Haven, Connecticut, United States | Gainesville, Florida, United States. This is a 2-arm, mul...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07216391" }, { "text": "Gamification Intervertion in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Gamification. Locations: Ankara, Yenimahalle, Turkey (Türkiye). Objective: This study aims to examine the effect of education provided through gamification methods on health literacy and q...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07409701" }, { "text": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System — RECRUITING, NA. Interventions: Omnipod 5 System, Omnipod 6 System. Locations: Los Angeles, California, United States | Santa Barbara, California, United States | Aurora, Colorado, United States. This multi-center, rando...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07579702" }, { "text": "Primary Care Pragmatic, Real World Experience for Automated Insulin Delivery — RECRUITING, NA. Interventions: Bionic Pancreas, Routine Care. Locations: Aurora, Colorado, United States | Boston, Massachusetts, United States. The goal of this randomized controlled trial is to compare the efficacy an...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07011147" }, { "text": "Physical Activity to Prevent and Treat Hyperglycemia From a Mistimed Bolus Insulin Dose — RECRUITING, NA. Interventions: Control (CON), Missed Dose (MISS), Missed Dose + 15min walk (MISS+EX). Locations: Montreal, Quebec, Canada. People living with type 1 diabetes (PwT1D) are recommended to administer insulin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06686329" }, { "text": "Washed Microbiota Transplantation for Type 1 Diabetes Mellitus — RECRUITING. Interventions: WMT. Locations: Nanjing, Jiangsu, China. This is a real-world study to explore the safety and the efficacy of washed microbiota transplantation (WMT) for patients with Type 1 Diabetes Mellitus...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06256614" }, { "text": "Insulin Therapy and Lipoproteins' Profile in Type 1 Diabetes. — RECRUITING. Locations: Poznan, Poland. The aim of the study is to evaluate the effect of insulin therapy in patients with newly diagnosed type 1 diabetes on quantitative and qualitative changes of plasma lipoproteins, w...", "sourceUrl": "https://clinicaltrials.gov/study/NCT02306005" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-09:research-watch", "slug": "2026-10-09-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-09T08:00:00.000Z", "updatedAt": "2026-10-09T23:17:01.739Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42427724.webp", "alt": "Detailed view of a microscope in a laboratory used in scientific research.", "credit": "indra projects (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/close-up-of-microscope-in-laboratory-setting-28570735/", "__contentHash": "d689cee94fe24a86513afadf4ad810dfa98f0b86e4e101b26276461b8e6ea475", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-09" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-08:daily-type-1-diabetes-briefing", "slug": "2026-10-08-daily-type-1-diabetes-briefing", "title": "October 8, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-08T08:00:00.000Z", "updatedAt": "2026-10-08T23:17:01.371Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42559751.webp", "alt": "High Blood Sugar Readings on Glucose Test Monitoring device", "credit": "JeepersMedia (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://www.flickr.com/photos/39160147@N03/16201714831", "__contentHash": "d32037e6c70bb5d3563970794b8a03bb281dea5d0b3ced4c55d0b420fe5a4d0e", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221918", "clinicaltrials:NCT07699380", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07742306", "openfda-device-recall:221103", "clinicaltrials:NCT07149142", "openfda-device-recall:221053" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)", "url": "https://clinicaltrials.gov/study/NCT07699380", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-15" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Continuous Glucose Monitoring in High-Risk Children and Youth With Type 1 Diabetes in the Dominican Republic", "url": "https://clinicaltrials.gov/study/NCT07742306", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07149142", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-20" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 8, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D) — RECRUITING, PHASE2. Interventions: AMX0035, Placebo. Locations: Seattle, Washington, United States | Amsterdam, Netherlands. The study is a randomized, double-blind, parallel-group clinical trial to examine the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07699380" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Continuous Glucose Monitoring in High-Risk Children and Youth With Type 1 Diabetes in the Dominican Republic — RECRUITING. Interventions: Intermittent CGM. Locations: Santiago de los Caballeros, Dominican Republic | Santo Domingo, Dominican Republic | Santo Domingo, Dominican Republic. The goal of this pilot longitudinal study i...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07742306" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 8, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-08:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-08-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-08T08:00:00.000Z", "updatedAt": "2026-10-08T23:17:01.371Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-6a679e86a359e744.webp", "alt": "Vaccine research center attached to a Kabul hospital in the 1960s. Original caption: \"A laboratory at the Vaccine Research Center.\"", "credit": "Unknown author Unknown author (Wikimedia Commons)", "license": "Public domain", "sourceUrl": "https://commons.wikimedia.org/wiki/File:1960s_Afghanistan_-_Laboratory_at_the_Vaccine_Research_Center.jpg", "__contentHash": "11ba1ffc53f484cffa0f6bda7bd8bc05a761993e2a0f03858fe76bd044131edc", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07699380", "clinicaltrials:NCT07038473", "clinicaltrials:NCT07742306", "clinicaltrials:NCT07149142", "clinicaltrials:NCT06296992", "clinicaltrials:NCT05899439", "clinicaltrials:NCT06217302", "clinicaltrials:NCT06405373", "clinicaltrials:NCT06994403", "clinicaltrials:NCT06496412" ], "sources": [ { "title": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D)", "url": "https://clinicaltrials.gov/study/NCT07699380", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-15" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Continuous Glucose Monitoring in High-Risk Children and Youth With Type 1 Diabetes in the Dominican Republic", "url": "https://clinicaltrials.gov/study/NCT07742306", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07149142", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-20" }, { "title": "Type 1 Diabetes, Exercise and Mentoring Trial", "url": "https://clinicaltrials.gov/study/NCT06296992", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-01" }, { "title": "Immune Function and the Progression to T1D", "url": "https://clinicaltrials.gov/study/NCT05899439", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-09" }, { "title": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease", "url": "https://clinicaltrials.gov/study/NCT06217302", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-24" }, { "title": "Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART", "url": "https://clinicaltrials.gov/study/NCT06405373", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-29" }, { "title": "Glycemic Response to Carbob-Enriched Pasta in Healthy and With Type 1 Diabetes People", "url": "https://clinicaltrials.gov/study/NCT06994403", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-29" }, { "title": "Safety and Efficacy of Fecal Microbiota Transplantation on Cognitive Function in T1DM", "url": "https://clinicaltrials.gov/study/NCT06496412", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-07-11" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "METabolic MODulation to Enhance Insulin Sensitivity and Mitochondrial Function in Type 1 Diabetes (MetMod-T1D) — RECRUITING, PHASE2. Interventions: AMX0035, Placebo. Locations: Seattle, Washington, United States | Amsterdam, Netherlands. The study is a randomized, double-blind, parallel-group clinical trial to examine the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07699380" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Continuous Glucose Monitoring in High-Risk Children and Youth With Type 1 Diabetes in the Dominican Republic — RECRUITING. Interventions: Intermittent CGM. Locations: Santiago de los Caballeros, Dominican Republic | Santo Domingo, Dominican Republic | Santo Domingo, Dominican Republic. The goal of this pilot longitudinal study i...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07742306" }, { "text": "Pediatric Artificial Intelligence for Retinopathy Screening in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Non-mydriatic fundus camera photography, Fundus ophtalmoscopy, Optic coherence tomography. Locations: Prague, Prague 5, Czechia. The proposed project is a clinical intervention trial testi...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07149142" }, { "text": "Type 1 Diabetes, Exercise and Mentoring Trial — RECRUITING, NA. Interventions: 12-week TEAM peer mentor program. Locations: Winnipeg, Manitoba, Canada | Mississauga, Ontario, Canada. The proposed study aims to improve the psychosocial health of adolescents living wit...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06296992" }, { "text": "Immune Function and the Progression to T1D — RECRUITING. Interventions: blood draw. Locations: Gainesville, Florida, United States | Columbus, Ohio, United States | Houston, Texas, United States. To elucidate the mechanisms by which type 1 diabetes-associated gene...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05899439" }, { "text": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — RECRUITING, PHASE3. Interventions: Sotagliflozin, Placebo. Locations: Stanford, California, United States | Aurora, Colorado, United States | Orlando, Florida, United States. Powerful new drugs that can prevent or delay...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06217302" }, { "text": "Behavioral Approaches to Reduce Diabetes Distress in Adults With Type 1 Diabetes: A Pragmatic SMART — RECRUITING, NA. Interventions: ReCharge, TakeCharge. Locations: Chapel Hill, North Carolina, United States. This study is designed to compare two behavioral approaches to reduce diabetes distress (\"the expected burdens,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06405373" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-08:research-watch", "slug": "2026-10-08-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-08T08:00:00.000Z", "updatedAt": "2026-10-08T23:17:01.371Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-9d921db3a1b8b376.webp", "alt": "Close-up of stained plant cells in onion root under microscope.", "credit": "Leo Freire (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/microscopic-view-of-plant-cells-in-onion-root-36372297/", "__contentHash": "53ec735ee21c5b6fc3393a5f646a021ebdad2e30c9ddc26880695f568483b509", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-08" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-07:daily-type-1-diabetes-briefing", "slug": "2026-10-07-daily-type-1-diabetes-briefing", "title": "October 7, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-07T08:00:00.000Z", "updatedAt": "2026-10-07T23:17:02.005Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42498455.webp", "alt": "Close-up of a woman's hands holding insulin pens. Perfect for health and diabetes-related content.", "credit": "Hannah Barata (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-woman-holding-three-bottles-of-nail-polish-27925628/", "__contentHash": "9b4b8ff29c9d3d1e8cd58f72dcd7ce155bb409071933f109717bd74ae571c85e", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221918", "clinicaltrials:NCT06820281", "clinicaltrials:NCT06273631", "clinicaltrials:NCT07498738", "clinicaltrials:NCT05414409", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06820281", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-16" }, { "title": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06273631", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-10" }, { "title": "Making Diabetes Care Fit for Young Adults Living With Type 1 Diabetes: Observations, Reflections and Expert Opinions", "url": "https://clinicaltrials.gov/study/NCT07498738", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-02" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 7, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Tirzepatide 2.5mg weekly, Placebo injection (normal saline). Locations: Sydney, New South Wales, Australia. This study will examine the effects of Tirzepatide (TZP), a glucagon-like pe...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06820281" }, { "text": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: diverse carbohydrate diet, moderate carbohydrate diet. Locations: Nanjing, Jiangsu, China. This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06273631" }, { "text": "Making Diabetes Care Fit for Young Adults Living With Type 1 Diabetes: Observations, Reflections and Expert Opinions — RECRUITING, NA. Interventions: Making Care Fit tool, Care as usual. Locations: Leiden, South Holland, Netherlands | Rotterdam, South Holland, Netherlands. The goal of this clinical study is to assess differences in coll...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07498738" }, { "text": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action — RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for comp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05414409" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 7, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-07:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-07-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-07T08:00:00.000Z", "updatedAt": "2026-10-07T23:17:02.005Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42431705.webp", "alt": "A healthcare professional administers an injection to an elderly patient in a hospital setting.", "credit": "Stéf -b. (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/nurse-with-syringe-10292621/", "__contentHash": "f2237f51e73f9010168d8a9ee0f2608fcf299506207dfac7b53098b7fd2ef205", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06820281", "clinicaltrials:NCT06273631", "clinicaltrials:NCT07498738", "clinicaltrials:NCT05414409", "clinicaltrials:NCT07341373", "clinicaltrials:NCT07434154", "clinicaltrials:NCT06852950", "clinicaltrials:NCT05454176", "clinicaltrials:NCT06731218", "clinicaltrials:NCT07125365" ], "sources": [ { "title": "Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06820281", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-16" }, { "title": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06273631", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-10" }, { "title": "Making Diabetes Care Fit for Young Adults Living With Type 1 Diabetes: Observations, Reflections and Expert Opinions", "url": "https://clinicaltrials.gov/study/NCT07498738", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-02" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500", "url": "https://clinicaltrials.gov/study/NCT07341373", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults", "url": "https://clinicaltrials.gov/study/NCT07434154", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-02" }, { "title": "Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge", "url": "https://clinicaltrials.gov/study/NCT06852950", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-05" }, { "title": "Diabetes in African Youth", "url": "https://clinicaltrials.gov/study/NCT05454176", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-11-25" }, { "title": "Phase I Clinical Study to Evaluate the Safety and Efficacy of RGB-5088 in Patients With Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT06731218", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-15" }, { "title": "UK Islet Autoantibody Registry", "url": "https://clinicaltrials.gov/study/NCT07125365", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-08-15" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Acute Metabolic Effects of Tirzepatide in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Tirzepatide 2.5mg weekly, Placebo injection (normal saline). Locations: Sydney, New South Wales, Australia. This study will examine the effects of Tirzepatide (TZP), a glucagon-like pe...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06820281" }, { "text": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: diverse carbohydrate diet, moderate carbohydrate diet. Locations: Nanjing, Jiangsu, China. This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06273631" }, { "text": "Making Diabetes Care Fit for Young Adults Living With Type 1 Diabetes: Observations, Reflections and Expert Opinions — RECRUITING, NA. Interventions: Making Care Fit tool, Care as usual. Locations: Leiden, South Holland, Netherlands | Rotterdam, South Holland, Netherlands. The goal of this clinical study is to assess differences in coll...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07498738" }, { "text": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action — RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for comp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05414409" }, { "text": "A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500 — RECRUITING, PHASE1. Interventions: Portal Insulin U-500, Portal Insulin U-500, Portal Insulin U-500. Locations: Chula Vista, California, United States. The goal of this clinical trial is to assess the safety of a new U5...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07341373" }, { "text": "Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults — RECRUITING. Locations: Pavia, Pavia, Italy. After obtaining informed consent, the investigators will recruit 75 patients with T1DM and 75 with LADA with an age ≥ 18 years and ≤ 75 years, of both sexes. All patients will...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07434154" }, { "text": "Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge — RECRUITING, NA. Interventions: Libre 3 Plus Continuous Glucose Monitor, Dexcom G7 Continuous Glucose Monitor. Locations: Nashville, Tennessee, United States. This study aims to improve patient awareness of the utility o...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06852950" }, { "text": "Diabetes in African Youth — RECRUITING, PHASE4. Interventions: Libre 2, Device for SMBG and Libre Pro. Locations: Minneapolis, Minnesota, United States. This RCT aims to improve T1D care in East African children and young adults by testing the hyp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05454176" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-07:research-watch", "slug": "2026-10-07-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-07T08:00:00.000Z", "updatedAt": "2026-10-07T23:17:02.005Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-a06c3facf0d18169.webp", "alt": "a group of red blood cells in a vein", "credit": "digitale.de (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/a-group-of-red-blood-cells-in-a-vein-S7-nZGW4-N8", "__contentHash": "11ad3b5184ea4c92572b8d133135badd091015e07e3097214b103cb9f8206cb2", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-07" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-06:daily-type-1-diabetes-briefing", "slug": "2026-10-06-daily-type-1-diabetes-briefing", "title": "October 6, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-06T08:00:00.000Z", "updatedAt": "2026-10-06T23:17:01.605Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42411938.webp", "alt": "A comprehensive flat lay of diabetes management tools including a glucose meter and instructional flyers.", "credit": "Pavel Danilyuk (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/flyers-and-glucose-meter-on-table-7653098/", "__contentHash": "0ce410d6e35577accf17bee03874103279a370216631d8d033577266b46e9029", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221918", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 6, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 6, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-06:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-06-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-06T08:00:00.000Z", "updatedAt": "2026-10-06T22:17:01.834Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42690941.webp", "alt": "British medics help earthquake-hit hospital in Kathmandu, Nepal", "credit": "DFID - UK Department for International Development (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://www.flickr.com/photos/14214150@N02/16720931664", "__contentHash": "a31d04b41647f128f70c5496f8386e8b3e55ecf418020dcdfc83634e36bac721", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07599982", "clinicaltrials:NCT06654713", "clinicaltrials:NCT05505669", "clinicaltrials:NCT07666789", "clinicaltrials:NCT07621445", "clinicaltrials:NCT06549023", "clinicaltrials:NCT07209930", "clinicaltrials:NCT06729242", "clinicaltrials:NCT06665815", "clinicaltrials:NCT06902597" ], "sources": [ { "title": "Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes", "url": "https://clinicaltrials.gov/study/NCT07599982", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-28" }, { "title": "Commercial or Open Source Closed Loop Impact on Pregnancy Study", "url": "https://clinicaltrials.gov/study/NCT06654713", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-27" }, { "title": "Circulating Biomarkers in the Development of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05505669", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-24" }, { "title": "Efficacy of Islet Re-transplantation After Failure of Beta-cell Replacement", "url": "https://clinicaltrials.gov/study/NCT07666789", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-24" }, { "title": "Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study", "url": "https://clinicaltrials.gov/study/NCT07621445", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-02" }, { "title": "Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy", "url": "https://clinicaltrials.gov/study/NCT06549023", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-11-18" }, { "title": "Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial", "url": "https://clinicaltrials.gov/study/NCT07209930", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-07" }, { "title": "Influence of Menstrual Cycle Phases on the Glycemic Control of Aerobic or HIIT Exercise in Adult Women With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06729242", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-08" }, { "title": "A National Screening Program for Islet Autoantibodies Among First-degree Relatives of T1D Patients", "url": "https://clinicaltrials.gov/study/NCT06665815", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-20" }, { "title": "Association Between Sarcopenia And Diabetic Neuropathy In Adults With Type 1 Diabetes, A Pilot Study", "url": "https://clinicaltrials.gov/study/NCT06902597", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-03-30" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes — RECRUITING, NA. Interventions: MODI Algorithm. Locations: Baltimore, Maryland, United States | Detroit, Michigan, United States | Albany, New York, United States. A 13-week multi-center single-arm trial, preceded by a 2...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07599982" }, { "text": "Commercial or Open Source Closed Loop Impact on Pregnancy Study — RECRUITING. Interventions: Commercial AID system, Open source AID system. Locations: San Francisco, California, United States. The goal of this observational study is to better understand what happens when pregnant peop...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06654713" }, { "text": "Circulating Biomarkers in the Development of Type 1 Diabetes — RECRUITING. Interventions: One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit.. Locations: Duarte, California, Un...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05505669" }, { "text": "Efficacy of Islet Re-transplantation After Failure of Beta-cell Replacement — RECRUITING. Locations: Montpellier, France. Islet transplantation and pancreas transplantation are established therapeutic options for selected individuals with type 1 diabetes experiencing severe glycemic instability a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07666789" }, { "text": "Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study — RECRUITING. Locations: Changsha, Hunan, China. The goal of this observational study is to evaluate the predictive value of the genetic risk score for type 1 diabetes in the progression to insulin deficiency in diabetic...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07621445" }, { "text": "Single Session vs Multiple-Session Panretinal Photocoagulation for Treatment of Proliferative Diabetic Retinopathy — RECRUITING, NA. Interventions: Single-session panretinal PRP (SS-PRP), Multiple-session panretinal PRP (MS-PRP). Locations: Mölndal, Sweden. Proliferative diabetic retinopathy (PDR) is the leading cause for blindness in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06549023" }, { "text": "Inter- and Intraindividual Variability of the Acute Glucose Response to Exercise in Healthy Adults and People Living With Type 1 Diabetes: A Cross-over Replicate Trial — RECRUITING, NA. Interventions: Exercise, Rest. Locations: Dublin, Dublin, Ireland. The goal of this clinical trial is to investigate if blood glucose responses are similar between and within individuals in response to s...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07209930" }, { "text": "Influence of Menstrual Cycle Phases on the Glycemic Control of Aerobic or HIIT Exercise in Adult Women With Type 1 Diabetes — RECRUITING, NA. Interventions: Aerobic session, HIIT session. Locations: Valencia, Select One, Spain. Continuous glucose monitors, as a technology that aims to improve glycaemic control in patients with type 1 diabetes,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06729242" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-06:research-watch", "slug": "2026-10-06-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-06T08:00:00.000Z", "updatedAt": "2026-10-06T23:17:01.605Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-e361baa0abe261e3.webp", "alt": "A dense cluster of red blood cells floating in a fluid medium", "credit": "Anirudh (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/red-blood-cells-floating-in-fluid-djo3iNJpaOE", "__contentHash": "1237a397bda519efc37981437018d66021c36a8c685c78384898401b819610d3", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-06" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-05:daily-type-1-diabetes-briefing", "slug": "2026-10-05-daily-type-1-diabetes-briefing", "title": "October 5, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-05T08:00:00.000Z", "updatedAt": "2026-10-05T23:17:01.697Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-e58a798874ce6cf9.webp", "alt": "Researchers conducting a scientific experiment with a syringe and petri dish in a lab setting.", "credit": "MART PRODUCTION (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/person-holding-silver-and-black-hand-tool-7230839/", "__contentHash": "681d2266572ec3f5d971cd97bc175c09d632d22d22d58e17e666a9cd51d50f31", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221918", "clinicaltrials:NCT06783309", "clinicaltrials:NCT06273631", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07409701", "openfda-device-recall:221103", "clinicaltrials:NCT07617519", "openfda-device-recall:221053" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)", "url": "https://clinicaltrials.gov/study/NCT06783309", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06273631", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-10" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Gamification Intervertion in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07409701", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Changing Outpatient Diabetes Care With Remote-Patient-Monitoring: A Real World Evidence Study With Pre-Post Comparison", "url": "https://clinicaltrials.gov/study/NCT07617519", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 5, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) — RECRUITING, PHASE1, PHASE2. Interventions: CNP-103, Placebo. Locations: Tucson, Arizona, United States | Tucson, Arizona, United States | Newport Beach, California, United States. This study is a Phase 1b/2a First-in-Hu...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06783309" }, { "text": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: diverse carbohydrate diet, moderate carbohydrate diet. Locations: Nanjing, Jiangsu, China. This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06273631" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Gamification Intervertion in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Gamification. Locations: Ankara, Yenimahalle, Turkey (Türkiye). Objective: This study aims to examine the effect of education provided through gamification methods on health literacy and q...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07409701" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 5, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-05:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-05-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-05T08:00:00.000Z", "updatedAt": "2026-10-05T23:17:01.697Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42516718.webp", "alt": "A healthcare professional in gloves provides treatment to a patient in a medical setting.", "credit": "Juan Manuel Montejano Lopez (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/patient-during-treatment-13538708/", "__contentHash": "b0daf0ac673a81560a5390699d312611f2786b816237a5648957a78fd293dd9b", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06783309", "clinicaltrials:NCT06273631", "clinicaltrials:NCT07409701", "clinicaltrials:NCT07617519", "clinicaltrials:NCT07518004", "clinicaltrials:NCT07258758", "clinicaltrials:NCT01630850", "clinicaltrials:NCT05454176", "clinicaltrials:NCT07126873", "clinicaltrials:NCT05610865" ], "sources": [ { "title": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)", "url": "https://clinicaltrials.gov/study/NCT06783309", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06273631", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-10" }, { "title": "Gamification Intervertion in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07409701", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-13" }, { "title": "Changing Outpatient Diabetes Care With Remote-Patient-Monitoring: A Real World Evidence Study With Pre-Post Comparison", "url": "https://clinicaltrials.gov/study/NCT07617519", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" }, { "title": "ROME GS System Study", "url": "https://clinicaltrials.gov/study/NCT07518004", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-21" }, { "title": "Diabetes Intervention Involving Person-centred Nutritional Education", "url": "https://clinicaltrials.gov/study/NCT07258758", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-12" }, { "title": "Islet Transplantation in Patients With \"Brittle\" Type I Diabetes", "url": "https://clinicaltrials.gov/study/NCT01630850", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-09" }, { "title": "Diabetes in African Youth", "url": "https://clinicaltrials.gov/study/NCT05454176", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-11-25" }, { "title": "A Safety, Tolerability, and Efficacy Study of E-islet 01 in Participants With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07126873", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-08-22" }, { "title": "Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers", "url": "https://clinicaltrials.gov/study/NCT05610865", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-31" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) — RECRUITING, PHASE1, PHASE2. Interventions: CNP-103, Placebo. Locations: Tucson, Arizona, United States | Tucson, Arizona, United States | Newport Beach, California, United States. This study is a Phase 1b/2a First-in-Hu...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06783309" }, { "text": "Effect of Different Carbohydrate Intake Patterns on Glycemic Control in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: diverse carbohydrate diet, moderate carbohydrate diet. Locations: Nanjing, Jiangsu, China. This multicenter, randomized, controlled, open-label clinical trial aims to evaluate the effects...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06273631" }, { "text": "Gamification Intervertion in Children With Type 1 Diabetes — RECRUITING, NA. Interventions: Gamification. Locations: Ankara, Yenimahalle, Turkey (Türkiye). Objective: This study aims to examine the effect of education provided through gamification methods on health literacy and q...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07409701" }, { "text": "Changing Outpatient Diabetes Care With Remote-Patient-Monitoring: A Real World Evidence Study With Pre-Post Comparison — RECRUITING. Interventions: Remote-Patient-Monitoring (RPM). Locations: Herlev, Denmark. The goal of this observational pre-post study is to evaluate a remote-patient-monitoring-system (RPM-system) integrated within an e...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07617519" }, { "text": "ROME GS System Study — RECRUITING, NA. Interventions: Continuous Glucose Monitoring System. Locations: Escondido, California, United States | Walnut Creek, California, United States | San Antonio, Texas, United States. The purpose of this cli...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07518004" }, { "text": "Diabetes Intervention Involving Person-centred Nutritional Education — RECRUITING, NA. Interventions: Dietary intervention. Locations: Enköping, Uppland, Sweden. The overall objective for this project is to evaluate the effects of a person-centred education intervention to promote a health...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07258758" }, { "text": "Islet Transplantation in Patients With \"Brittle\" Type I Diabetes — RECRUITING, NA. Interventions: Allogenic islet cells (human, U. Chicago), Intraportal infusion of islet cells. Locations: Chicago, Illinois, United States. The purpose of this study is to learn about the safety of islet...", "sourceUrl": "https://clinicaltrials.gov/study/NCT01630850" }, { "text": "Diabetes in African Youth — RECRUITING, PHASE4. Interventions: Libre 2, Device for SMBG and Libre Pro. Locations: Minneapolis, Minnesota, United States. This RCT aims to improve T1D care in East African children and young adults by testing the hyp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05454176" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-05:research-watch", "slug": "2026-10-05-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-05T08:00:00.000Z", "updatedAt": "2026-10-05T23:17:01.697Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-f93ad90d4323876a.webp", "alt": "Female scientist using a microscope in a laboratory environment, focusing on research.", "credit": "Thirdman (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-side-view-of-a-woman-looking-at-the-microscope-8940356/", "__contentHash": "3bde415da8b150519249b145d156875919967be8305bf43de6d9fd5c43c0b913", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42830429" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" }, { "title": "Glycaemic Variability and C-Peptide in Bangladeshi Children, Adolescents, and Young Adults With Diabetes: A Prospective Study.", "url": "https://pubmed.ncbi.nlm.nih.gov/42830429/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-05" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-04:research-watch", "slug": "2026-10-04-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-04T08:00:00.000Z", "updatedAt": "2026-10-04T23:17:01.749Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42371338.webp", "alt": "A cluster of translucent purple cells with glowing pink nuclei on a purple background", "credit": "Esma Melike Sezer (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/purple-cells-with-glowing-nuclei-TKzFq5beVb0", "__contentHash": "9f4cef78ae5d4cc05e06bc952d774f323ad281fd10157caa8f9f298ff137e11d", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42820064" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" }, { "title": "The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact.", "url": "https://pubmed.ncbi.nlm.nih.gov/42820064/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-04" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-03:research-watch", "slug": "2026-10-03-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-03T08:00:00.000Z", "updatedAt": "2026-10-03T23:17:01.230Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42375328.webp", "alt": "A series of microscopes on a lab table, ideal for scientific research and education.", "credit": "Vladimir Srajber (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/microscopes-on-the-floor-15290006/", "__contentHash": "07fad44de7983118abd042f19da1feebd82acb28d940bf45d728ffe6e81fb194", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42820064" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" }, { "title": "The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact.", "url": "https://pubmed.ncbi.nlm.nih.gov/42820064/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-03" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-02:daily-type-1-diabetes-briefing", "slug": "2026-10-02-daily-type-1-diabetes-briefing", "title": "October 2, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-02T08:00:00.000Z", "updatedAt": "2026-10-02T23:17:01.520Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42605527.webp", "alt": "A blood glucose meter with a lancing device and test strips on white", "credit": "Jane Korsak (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/blood-glucose-meter-with-test-strips-BlgBBf_b_94", "__contentHash": "2419047fe1a63230fc58de1222a2bcdcda774b0473e54dddb8d554014f397f4d", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221918", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "clinicaltrials:NCT07048795", "openfda-device-recall:221053", "clinicaltrials:NCT06791291", "openfda-device-recall:220614", "openfda-device-recall:220615" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France", "url": "https://clinicaltrials.gov/study/NCT07048795", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-09" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06791291", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-01" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 2, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France — RECRUITING. Interventions: No Intervention: Observational Cohort. Locations: Amiens, France | Angers, France | Argenteuil, France. This is a non-interventional, longitudinal, prospective, multicenter, post market-regist...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07048795" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 2, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-02:device-safety-watch", "slug": "2026-10-02-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-02T08:00:00.000Z", "updatedAt": "2026-10-02T23:17:01.520Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42422449.webp", "alt": "A digital glucometer and lancing device on a wooden surface indicating high blood glucose level.", "credit": "Arunangshu Banerjee (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/digital-glucose-monitor-on-wooden-surface-33200681/", "__contentHash": "2d5e89661e7ff8d534cff920675f5483f43e25fac690711e3486495680bca64f", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221918", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2.... — A beta (early-release) version of the iOS application, version 2.13 (TestFlight) had a software issue preventing successful pairing of the t:slim application with Abbott FreeStyle Libre 3 Plus (FSL3P) continuous glucose...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-10-02:how-type1cure-labels-evidence", "slug": "2026-10-02-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-02T08:00:00.000Z", "updatedAt": "2026-10-02T23:17:01.520Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42467087.webp", "alt": "Healthcare professional reviews medical form during patient consultation in a clinic setting.", "credit": "MART PRODUCTION (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/hands-doctor-health-anonymous-7088834/", "__contentHash": "aaa97235ab02eb57f46de5c6c98f565dbb0bedcf36ecefbd72e9d198fbed5dca", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "openfda-device-recall:221918", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "clinicaltrials:NCT07048795" ], "sources": [ { "title": "Tandem Diabetes Care, Inc.: Brand Name: Tandem t:slim mobile application Product Name: t:slim Mobile Application, iOS Model/Catalog Number: iOS software version 2.13 Software Version: iOS software version 2....", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221918", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-09-29" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France", "url": "https://clinicaltrials.gov/study/NCT07048795", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-09" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-10-02:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-02-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-02T08:00:00.000Z", "updatedAt": "2026-10-02T23:17:01.520Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42456777.webp", "alt": "Doctor checking patient's vitals in a clinical setting for health consultation.", "credit": "Los Muertos Crew (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-man-sitting-on-blue-bed-8460125/", "__contentHash": "ac56e56d8fc4d5f79e481e17126d115c6282b0f93d54dd169f2d1904e7df8ca8", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07048795", "clinicaltrials:NCT06791291", "clinicaltrials:NCT06624046", "clinicaltrials:NCT07621445", "clinicaltrials:NCT05054361", "clinicaltrials:NCT07434154", "clinicaltrials:NCT06198725", "clinicaltrials:NCT07185555", "clinicaltrials:NCT06256614", "clinicaltrials:NCT07126873" ], "sources": [ { "title": "Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France", "url": "https://clinicaltrials.gov/study/NCT07048795", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-09" }, { "title": "Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06791291", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-01" }, { "title": "Circadian Mechanisms, Glucose, and CV Risks in T1D", "url": "https://clinicaltrials.gov/study/NCT06624046", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-30" }, { "title": "Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study", "url": "https://clinicaltrials.gov/study/NCT07621445", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-02" }, { "title": "Crosstalk Between Mucosal-Associated Invariant T (MAIT) Cells and the Gut Microbiota and Mucosa in the Development of Type 1 Diabetes in Children", "url": "https://clinicaltrials.gov/study/NCT05054361", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-13" }, { "title": "Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults", "url": "https://clinicaltrials.gov/study/NCT07434154", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-02" }, { "title": "Intervention for Children With Type 1 Diabetes Targeting Gut Microbes", "url": "https://clinicaltrials.gov/study/NCT06198725", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-17" }, { "title": "Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System", "url": "https://clinicaltrials.gov/study/NCT07185555", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-29" }, { "title": "Washed Microbiota Transplantation for Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT06256614", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-10" }, { "title": "A Safety, Tolerability, and Efficacy Study of E-islet 01 in Participants With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07126873", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-08-22" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Impact of the Mylife CamAPS FX System With the DEXCOM G6 Sensor on T1D Patients in France — RECRUITING. Interventions: No Intervention: Observational Cohort. Locations: Amiens, France | Angers, France | Argenteuil, France. This is a non-interventional, longitudinal, prospective, multicenter, post market-regist...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07048795" }, { "text": "Efficacy and Safety of Teplizumab in Japanese Participants With Stage 2 Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Teplizumab. Locations: Ichikawa, Chiba, Japan | Sapporo, Hokkaido, Japan | Kobe, Hyōgo, Japan. This is a parallel, Phase 2, two-arm study to assess the efficacy and safety of 14-days i...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06791291" }, { "text": "Circadian Mechanisms, Glucose, and CV Risks in T1D — RECRUITING, NA. Interventions: Sleep stability intervention. Locations: Chicago, Illinois, United States. People with type 1 diabetes are disproportionately affected by cardiovascular disease (CVD). Short and irregular...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06624046" }, { "text": "Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study — RECRUITING. Locations: Changsha, Hunan, China. The goal of this observational study is to evaluate the predictive value of the genetic risk score for type 1 diabetes in the progression to insulin deficiency in diabetic...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07621445" }, { "text": "Crosstalk Between Mucosal-Associated Invariant T (MAIT) Cells and the Gut Microbiota and Mucosa in the Development of Type 1 Diabetes in Children — RECRUITING. Interventions: MAIT cells analysis, MAIT cytokines production analysis, Lactulose/Mannitol Test. Locations: Antony, France | Paris, France. To investigate in a prospective way changes in Mucosal-Associated I...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05054361" }, { "text": "Evaluation of Oxidative Stress: Comparison Between Type 1 Diabetes Mellitus and Latent Autoimmune Diabetes in Adults — RECRUITING. Locations: Pavia, Pavia, Italy. After obtaining informed consent, the investigators will recruit 75 patients with T1DM and 75 with LADA with an age ≥ 18 years and ≤ 75 years, of both sexes. All patients will...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07434154" }, { "text": "Intervention for Children With Type 1 Diabetes Targeting Gut Microbes — RECRUITING, NA. Interventions: Trimtab. Locations: Shanghai, Shanghai Municipality, China. The goal of this clinical study is to evaluate the effect of nutritional intervention program based on dietary products in the c...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06198725" }, { "text": "Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System — RECRUITING, NA. Interventions: VLEKT. Locations: Bari, Italy, Italy. Overweight and obesity are frequent in adults with type 1 diabetes (T1D), with prevalence exceeding 50% in recent studies. Excess weight in T1D is ass...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07185555" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-02:research-watch", "slug": "2026-10-02-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-02T08:00:00.000Z", "updatedAt": "2026-10-02T23:17:01.520Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-78d6cc3c8cc8a775.webp", "alt": "Two scientists in a lab examining samples with a microscope. Focus on scientific research and discovery.", "credit": "Edward Jenner (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/woman-using-the-microscope-4031321/", "__contentHash": "d2b846c583c30d74d6483319be9b62816701ca27e7cd94ec26fbcf24bdc9d942", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42790360", "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42820064" ], "sources": [ { "title": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42790360/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" }, { "title": "The Immune Checkpoint Inhibitors Journey: From Early Promise to Lasting Impact.", "url": "https://pubmed.ncbi.nlm.nih.gov/42820064/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-02" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Engineering a bijel-templated material-integrated cannula for subcutaneous insulin delivery: Design, fabrication, in vivo delivery characterization, and failure analysis. — Biomaterials advances. Authors: Groisman L, Thorson TJ, Saudi B. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42790360/" }, { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-10-01:daily-type-1-diabetes-briefing", "slug": "2026-10-01-daily-type-1-diabetes-briefing", "title": "October 1, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-01T08:00:00.000Z", "updatedAt": "2026-10-01T10:17:01.578Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42461833.webp", "alt": "A Blood-Glucose-Powered Metabolic Fuel Cell for Self-Sufficient Bioelectronics", "credit": "Authors of the study: Debasis Maity, Preetam Guha Ray, Peter Buchmann, Maysam Mansouri, Martin Fussenegger (Openverse / BY 4.0)", "license": "Openverse BY 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=131675501", "__contentHash": "8763f598b7bf522c21855c96dac6b770c987572cbeed7d7f908c64c89e73e5c8", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07222332", "clinicaltrials:NCT07804849", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07579702", "openfda-device-recall:221103", "clinicaltrials:NCT05188014", "clinicaltrials:NCT07667504", "openfda-device-recall:221053" ], "sources": [ { "title": "A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)", "url": "https://clinicaltrials.gov/study/NCT07222332", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System", "url": "https://clinicaltrials.gov/study/NCT07579702", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-03" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Exercise and the Menstrual Cycle in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05188014", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-20" }, { "title": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07667504", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-15" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The October 1, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE) — RECRUITING, PHASE3. Interventions: Baricitinib, Placebo. Locations: Aurora, Colorado, United States | Tallahassee, Florida, United States | Philadelphia, Pennsylvania, United States. The purpose of this study is to find...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07222332" }, { "text": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes — RECRUITING, PHASE2, PHASE3. Interventions: Verapamil oral, Placebo. Locations: Cairo, Egypt. Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verap...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07804849" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System — RECRUITING, NA. Interventions: Omnipod 5 System, Omnipod 6 System. Locations: Los Angeles, California, United States | Santa Barbara, California, United States | Aurora, Colorado, United States. This multi-center, rando...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07579702" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "October 1, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-10-01:device-safety-watch", "slug": "2026-10-01-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-01T08:00:00.000Z", "updatedAt": "2026-10-01T10:17:01.578Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42433374.webp", "alt": "File:Blood Pressure And Blood Glucose Test - Health Check-up Camp - NCSM - Salt Lake City - Kolkata 2017-06-21 2950.JPG", "credit": "Biswarup Ganguly (Openverse / BY 3.0)", "license": "Openverse BY 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=60557626", "__contentHash": "fd508688ff660f91b9d1b52cddf51ee9a15d2f11559049170ec7034cc7992a8e", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-10-01:how-type1cure-labels-evidence", "slug": "2026-10-01-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-01T08:00:00.000Z", "updatedAt": "2026-10-01T10:17:01.578Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42404286.webp", "alt": "A cluster of medical syringes with blue fluid, ideal for healthcare and vaccination themes.", "credit": "Tara Winstead (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/white-and-orange-tube-bottles-7723205/", "__contentHash": "a6a3809a8908e4bd35deb22f441910d0049be461a6ee07bf0dd306cf63ac5c6f", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT07222332", "clinicaltrials:NCT07804849", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07579702" ], "sources": [ { "title": "A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)", "url": "https://clinicaltrials.gov/study/NCT07222332", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System", "url": "https://clinicaltrials.gov/study/NCT07579702", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-03" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-10-01:recruiting-type-1-diabetes-trials-watch", "slug": "2026-10-01-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-01T08:00:00.000Z", "updatedAt": "2026-10-01T10:17:01.578Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42445883.webp", "alt": "Khaschuvate Complex of District Hospital Medical Laboratory 01 (YDS 0551)", "credit": "Nataliya Shestakova (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=62224204", "__contentHash": "0da49dc9da833f83d321301573657f14fdaec59519ac2cbc24f36baf2242d2b3", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07222332", "clinicaltrials:NCT07804849", "clinicaltrials:NCT07579702", "clinicaltrials:NCT05188014", "clinicaltrials:NCT07667504", "clinicaltrials:NCT03528226", "clinicaltrials:NCT05188027", "clinicaltrials:NCT06630585" ], "sources": [ { "title": "A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE)", "url": "https://clinicaltrials.gov/study/NCT07222332", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System", "url": "https://clinicaltrials.gov/study/NCT07579702", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-03" }, { "title": "Exercise and the Menstrual Cycle in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05188014", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-20" }, { "title": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07667504", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-15" }, { "title": "Exercise Training and Endothelial Function in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT03528226", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-14" }, { "title": "Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05188027", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-16" }, { "title": "GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06630585", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-26" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "A Study of Baricitinib (LY3009104) to Preserve Beta Cell Function in Children and Adults Newly Diagnosed With Type 1 Diabetes (BARICADE-PRESERVE) — RECRUITING, PHASE3. Interventions: Baricitinib, Placebo. Locations: Aurora, Colorado, United States | Tallahassee, Florida, United States | Philadelphia, Pennsylvania, United States. The purpose of this study is to find...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07222332" }, { "text": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes — RECRUITING, PHASE2, PHASE3. Interventions: Verapamil oral, Placebo. Locations: Cairo, Egypt. Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verap...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07804849" }, { "text": "Efficacy of the Omnipod® 6 System Compared With the Omnipod® 5 System — RECRUITING, NA. Interventions: Omnipod 5 System, Omnipod 6 System. Locations: Los Angeles, California, United States | Santa Barbara, California, United States | Aurora, Colorado, United States. This multi-center, rando...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07579702" }, { "text": "Exercise and the Menstrual Cycle in Type 1 Diabetes — RECRUITING, NA. Interventions: Luteal Phase Aerobic Exercise, Follicular Phase Aerobic Exercise. Locations: Edmonton, Alberta, Canada. Female participants with type 1 diabetes using oral contraceptives will be asked to...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05188014" }, { "text": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes — RECRUITING, NA. Interventions: Moderate carbohydrate restriction, Early time-restricted eating, Standard calorie restriction. Locations: Málaga, Málaga, Spain. Although type 1 diabetes (T1D) has traditionally been consi...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07667504" }, { "text": "Exercise Training and Endothelial Function in Type 1 Diabetes — RECRUITING, NA. Interventions: Exercise Training Procedure, Normal life procedure. Locations: Lille, France. Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03528226" }, { "text": "Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes — RECRUITING, NA. Interventions: Aerobic Exercise, Resistance Exercise, No exercise. Locations: Edmonton, Alberta, Canada | Montreal, Quebec, Canada. Participants will be asked to wear a continuous glucose monitor for at...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05188027" }, { "text": "GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes — RECRUITING, PHASE3. Interventions: Tirzepatide. Locations: Chêne-Bougeries, Canton of Geneva, Switzerland | Olten, Canton of Solothurn, Switzerland | Lucerne, Switzerland. Blood glucose management in type 1 diabetes (T1...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06630585" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-10-01:research-watch", "slug": "2026-10-01-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-10-01T08:00:00.000Z", "updatedAt": "2026-10-01T10:17:01.578Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-8a6c4fb8b02b2282.webp", "alt": "File:Stem cells diagram EST.png", "credit": "Mike Jones (Openverse / BY-SA 2.5)", "license": "Openverse BY-SA 2.5", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=36503611", "__contentHash": "33cf2665ecead2d4aece52ea3b3fe7a1ad611918ce647208a3d5c6bb3fc4d36f", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42667390" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" }, { "title": "Metabolic and macrovascular outcomes following simultaneous pancreas-kidney transplantation and kidney transplantation alone in recipients with type 1 diabetes mellitus: a systematic review and meta-analysis.", "url": "https://pubmed.ncbi.nlm.nih.gov/42667390/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-10-01" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-30:daily-type-1-diabetes-briefing", "slug": "2026-09-30-daily-type-1-diabetes-briefing", "title": "September 30, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-30T08:00:00.000Z", "updatedAt": "2026-09-30T10:17:01.353Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-e26b5dc7b1ccf5f7.webp", "alt": "Medical research setup featuring anatomical models, x-rays, and a textbook, ideal for educational purposes.", "credit": "Tara Winstead (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/black-smartphone-on-white-and-red-book-7723391/", "__contentHash": "c359a6e115f639ab8ca361d42d6b0751420dd80ccc06cbed983e2aaa3db29f58", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT06739811", "clinicaltrials:NCT06783309", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07463209", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615" ], "sources": [ { "title": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)", "url": "https://clinicaltrials.gov/study/NCT06739811", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)", "url": "https://clinicaltrials.gov/study/NCT06783309", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Integrating New Skills Into Diabetes Education With CGM", "url": "https://clinicaltrials.gov/study/NCT07463209", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-14" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 30, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347) — RECRUITING, NA. Interventions: Implantable Insulin Pump System. Locations: Bordeaux, France, France | Corbeil-Essonnes, France, France | Lille, France, France. The purpose of this study is to evaluate the clinical perfo...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06739811" }, { "text": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) — RECRUITING, PHASE1, PHASE2. Interventions: CNP-103, Placebo. Locations: Tucson, Arizona, United States | Tucson, Arizona, United States | Newport Beach, California, United States. This study is a Phase 1b/2a First-in-Hu...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06783309" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Integrating New Skills Into Diabetes Education With CGM — RECRUITING, NA. Interventions: Three-stage CGM integration program, One-time clinic-based CGM training, Self-directed CGM training. Locations: Chapel Hill, North Carolina, United States. This study is designed to test t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07463209" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 30, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-30:device-safety-watch", "slug": "2026-09-30-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-30T08:00:00.000Z", "updatedAt": "2026-09-30T10:17:01.353Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42444980.webp", "alt": "File:Blood Pressure And Blood Glucose Test - Health Check-up Camp - NCSM - Salt Lake City - Kolkata 2017-06-21 2947.JPG", "credit": "Biswarup Ganguly (Openverse / BY 3.0)", "license": "Openverse BY 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=60557550", "__contentHash": "cf4938656baa6c27597392d53a6839fc72910dacc224055dd23e053842078177", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-30:how-type1cure-labels-evidence", "slug": "2026-09-30-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-30T08:00:00.000Z", "updatedAt": "2026-09-30T10:17:01.353Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42547586.webp", "alt": "Flat lay of blood pressure monitor, pills, and ECG printout for heart health theme.", "credit": "Marta Branco (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/medical-devices-and-pills-on-ecg-printout-32236830/", "__contentHash": "f09ae65462c68c82f7a9de98f2e3e67229b602e67a3447a6bd64e90148e203e7", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT06739811", "clinicaltrials:NCT06783309", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07463209" ], "sources": [ { "title": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)", "url": "https://clinicaltrials.gov/study/NCT06739811", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)", "url": "https://clinicaltrials.gov/study/NCT06783309", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Integrating New Skills Into Diabetes Education With CGM", "url": "https://clinicaltrials.gov/study/NCT07463209", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-14" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-30:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-30-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-30T08:00:00.000Z", "updatedAt": "2026-09-30T10:17:01.353Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42524461.webp", "alt": "Pensive man nurse in blue uniform standing and demonstrating diagnosis to serious African American female patient in hallway of hospital in daytime", "credit": "Klaus Nielsen (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/doctor-showing-diagnosis-to-black-woman-patient-in-hallway-of-clinic-6303645/", "__contentHash": "a0152c4dab329e99e3d79663db9ff7db0d882be18802bf7f66e3764e1308117f", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06739811", "clinicaltrials:NCT06783309", "clinicaltrials:NCT07463209", "clinicaltrials:NCT04963777", "clinicaltrials:NCT04334707", "clinicaltrials:NCT06936280", "clinicaltrials:NCT06338553", "clinicaltrials:NCT05984979", "clinicaltrials:NCT06752928", "clinicaltrials:NCT07051564" ], "sources": [ { "title": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)", "url": "https://clinicaltrials.gov/study/NCT06739811", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D)", "url": "https://clinicaltrials.gov/study/NCT06783309", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-11" }, { "title": "Integrating New Skills Into Diabetes Education With CGM", "url": "https://clinicaltrials.gov/study/NCT07463209", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-14" }, { "title": "Prebiotics in Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04963777", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-01" }, { "title": "Kidney Precision Medicine Project", "url": "https://clinicaltrials.gov/study/NCT04334707", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-14" }, { "title": "Type 1 Diabetes and Diabetes Distress", "url": "https://clinicaltrials.gov/study/NCT06936280", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-09" }, { "title": "GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab", "url": "https://clinicaltrials.gov/study/NCT06338553", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-18" }, { "title": "The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes", "url": "https://clinicaltrials.gov/study/NCT05984979", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-08" }, { "title": "A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06752928", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-08" }, { "title": "Clinical Study on the Treatment of Type 1 Diabetes With CNK-UT009 Cell Injection", "url": "https://clinicaltrials.gov/study/NCT07051564", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-04" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347) — RECRUITING, NA. Interventions: Implantable Insulin Pump System. Locations: Bordeaux, France, France | Corbeil-Essonnes, France, France | Lille, France, France. The purpose of this study is to evaluate the clinical perfo...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06739811" }, { "text": "CNP-103 in Adolescent and Adult Subjects Ages 12-35 With Recently Diagnosed (Within 6 Months) Stage 3 Type 1 Diabetes (T1D) — RECRUITING, PHASE1, PHASE2. Interventions: CNP-103, Placebo. Locations: Tucson, Arizona, United States | Tucson, Arizona, United States | Newport Beach, California, United States. This study is a Phase 1b/2a First-in-Hu...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06783309" }, { "text": "Integrating New Skills Into Diabetes Education With CGM — RECRUITING, NA. Interventions: Three-stage CGM integration program, One-time clinic-based CGM training, Self-directed CGM training. Locations: Chapel Hill, North Carolina, United States. This study is designed to test t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07463209" }, { "text": "Prebiotics in Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: Prebiotic, Placebo. Locations: Calgary, Alberta, Canada | Edmonton, Alberta, Canada | Saskatoon, Saskatchewan, Canada. Evidence suggests that prebiotic fibre can correct dysbiosis, reduce...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04963777" }, { "text": "Kidney Precision Medicine Project — RECRUITING. Interventions: Kidney Biopsy, MRI, Retina Scan. Locations: Tucson, Arizona, United States | New Haven, Connecticut, United States | Chicago, Illinois, United States. Acute kidney injury (AKI) and chronic kid...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04334707" }, { "text": "Type 1 Diabetes and Diabetes Distress — RECRUITING, NA. Interventions: ACTnow. Locations: Esbjerg, Denmark | Odense, Denmark | Sønderborg, Denmark. The goal of this clinical trial is to reduce diabetes distress in emerging adults (18-35 years) with type 1 dia...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06936280" }, { "text": "GLP-1Ra Impact on Metabolic Outcomes in Stage 2 T1DM While Receiving Teplizumab — RECRUITING, EARLY_PHASE1. Interventions: Semaglutide (Rybelsus®), Placebo. Locations: Nashville, Tennessee, United States. The goal of this study is to determine how a drug class called glucagon-like peptide-1 receptor...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06338553" }, { "text": "The Daytime Circadian Rhythm in Exhaled Volatile Organic Compounds in People Living Without and Diabetes — RECRUITING. Interventions: Standardized meal. Locations: Bern, Switzerland. Exhaled volatile organic compounds will be measured during daytime with the goal to identifying circadian variability. The study incudes three...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05984979" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-30:research-watch", "slug": "2026-09-30-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-30T08:00:00.000Z", "updatedAt": "2026-09-30T10:17:01.353Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42697977.webp", "alt": "Close-up of labeled blood collection tubes in a laboratory with red, purple, and green caps.", "credit": "Stéf -b. (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/colorful-blood-collection-tubes-in-lab-setting-39459059/", "__contentHash": "53b60a4310d391416e7d4638e077f318b1216b2f5567cdcff59379a8b6bb2b88", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-30" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-29:daily-type-1-diabetes-briefing", "slug": "2026-09-29-daily-type-1-diabetes-briefing", "title": "September 29, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-29T08:00:00.000Z", "updatedAt": "2026-09-29T10:17:01.689Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42591790.webp", "alt": "Insulin pen and its packaging are shown.", "credit": "Haberdoedas (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/insulin-pen-and-its-packaging-are-shown-S5y5jdRCCsk", "__contentHash": "c748cd8a29dd8040ca8ee29d1b837739a85867d1bec4c65b42bf6c32ca272569", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT06860516", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07463209", "openfda-device-recall:221103", "clinicaltrials:NCT07667504", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615" ], "sources": [ { "title": "HLA Demographics Study in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06860516", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-28" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Integrating New Skills Into Diabetes Education With CGM", "url": "https://clinicaltrials.gov/study/NCT07463209", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-14" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07667504", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-15" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 29, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "HLA Demographics Study in Adults With Type 1 Diabetes — RECRUITING. Interventions: blood draw or cheek swab. Locations: San Francisco, California, United States | Gainesville, Florida, United States | Boston, Massachusetts, United States. This is a study to evaluate the HLA-...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06860516" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Integrating New Skills Into Diabetes Education With CGM — RECRUITING, NA. Interventions: Three-stage CGM integration program, One-time clinic-based CGM training, Self-directed CGM training. Locations: Chapel Hill, North Carolina, United States. This study is designed to test t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07463209" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes — RECRUITING, NA. Interventions: Moderate carbohydrate restriction, Early time-restricted eating, Standard calorie restriction. Locations: Málaga, Málaga, Spain. Although type 1 diabetes (T1D) has traditionally been consi...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07667504" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 29, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-29:device-safety-watch", "slug": "2026-09-29-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-29T08:00:00.000Z", "updatedAt": "2026-09-29T10:17:01.689Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42588158.webp", "alt": "High Blood Sugar glucose over 200mg Test Results Readings Meter, 1/2015 by Mike Mozart of TheToyChannel and JeepersMedia on YouTube #High #Blood #Sugar #Glucose", "credit": "JeepersMedia (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://www.flickr.com/photos/39160147@N03/16252925152", "__contentHash": "f713d5464b56adfd653746ef2277e04e0638962a3ea030fc5c45dcf11d74d833", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-29:how-type1cure-labels-evidence", "slug": "2026-09-29-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-29T08:00:00.000Z", "updatedAt": "2026-09-29T10:17:01.689Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-pmid-42468608.webp", "alt": "Flat lay of diabetes tools, green apple, almonds, and notebook for health planning.", "credit": "Towfiqu barbhuiya (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/green-apple-beside-white-electronic-device-11337257/", "__contentHash": "3b2c952cf178fd2248c8742f243c48988acbf4f1c0f212c3d6fdf91f57fc73ae", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT06860516", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07463209", "openfda-device-recall:221103" ], "sources": [ { "title": "HLA Demographics Study in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06860516", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-28" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Integrating New Skills Into Diabetes Education With CGM", "url": "https://clinicaltrials.gov/study/NCT07463209", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-14" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-29:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-29-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-29T08:00:00.000Z", "updatedAt": "2026-09-29T10:17:01.689Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42455227.webp", "alt": "Unrecognizable man wearing medical uniform with stethoscope and pens standing in hospital with crossed arms during work in day time", "credit": "https://kaboompics.com/ (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/crop-doctor-with-stethoscope-in-hospital-4021779/", "__contentHash": "f5f968835934b6f51205566d6c4e2d15ce4a16a986450499285226e4c3e013be", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06860516", "clinicaltrials:NCT07463209", "clinicaltrials:NCT07667504", "clinicaltrials:NCT06474598", "clinicaltrials:NCT06630585", "clinicaltrials:NCT07185555", "clinicaltrials:NCT05286892", "clinicaltrials:NCT06496412", "clinicaltrials:NCT05546138", "clinicaltrials:NCT06141434" ], "sources": [ { "title": "HLA Demographics Study in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06860516", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-28" }, { "title": "Integrating New Skills Into Diabetes Education With CGM", "url": "https://clinicaltrials.gov/study/NCT07463209", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-14" }, { "title": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07667504", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-15" }, { "title": "An Adaptive Design Study of MTX228", "url": "https://clinicaltrials.gov/study/NCT06474598", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-13" }, { "title": "GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06630585", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-26" }, { "title": "Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System", "url": "https://clinicaltrials.gov/study/NCT07185555", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-29" }, { "title": "Diabetes Learning in Virtual Environments Just in Time for Community Reentry", "url": "https://clinicaltrials.gov/study/NCT05286892", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-28" }, { "title": "Safety and Efficacy of Fecal Microbiota Transplantation on Cognitive Function in T1DM", "url": "https://clinicaltrials.gov/study/NCT06496412", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-07-11" }, { "title": "Characterization and Prediction of Early Onset Diabetic Peripheral Neuropathy", "url": "https://clinicaltrials.gov/study/NCT05546138", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-06-28" }, { "title": "PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life", "url": "https://clinicaltrials.gov/study/NCT06141434", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2023-11-21" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "HLA Demographics Study in Adults With Type 1 Diabetes — RECRUITING. Interventions: blood draw or cheek swab. Locations: San Francisco, California, United States | Gainesville, Florida, United States | Boston, Massachusetts, United States. This is a study to evaluate the HLA-...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06860516" }, { "text": "Integrating New Skills Into Diabetes Education With CGM — RECRUITING, NA. Interventions: Three-stage CGM integration program, One-time clinic-based CGM training, Self-directed CGM training. Locations: Chapel Hill, North Carolina, United States. This study is designed to test t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07463209" }, { "text": "Dietary Approaches for the Management of Overweight and Obesity in Type 1 Diabetes — RECRUITING, NA. Interventions: Moderate carbohydrate restriction, Early time-restricted eating, Standard calorie restriction. Locations: Málaga, Málaga, Spain. Although type 1 diabetes (T1D) has traditionally been consi...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07667504" }, { "text": "An Adaptive Design Study of MTX228 — RECRUITING, PHASE2. Interventions: MTX228, DEXCOM G6. Locations: Edmonton, Alberta, Canada. MTX228 has been identified as a medication that might allow the re-growth of insulin producing beta cells in people with Type 1...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06474598" }, { "text": "GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes — RECRUITING, PHASE3. Interventions: Tirzepatide. Locations: Chêne-Bougeries, Canton of Geneva, Switzerland | Olten, Canton of Solothurn, Switzerland | Lucerne, Switzerland. Blood glucose management in type 1 diabetes (T1...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06630585" }, { "text": "Vey Low-Energy Ketogenic Therapy in Adults With Type 1 Diabetes and Obesity on Intensive Insulin Therapy Using Advanded Hybrid Closed Loop System — RECRUITING, NA. Interventions: VLEKT. Locations: Bari, Italy, Italy. Overweight and obesity are frequent in adults with type 1 diabetes (T1D), with prevalence exceeding 50% in recent studies. Excess weight in T1D is ass...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07185555" }, { "text": "Diabetes Learning in Virtual Environments Just in Time for Community Reentry — RECRUITING, NA. Interventions: Diabetes LIVE JustICE, Enhanced Education. Locations: Storrs, Connecticut, United States | Storrs Mansfield, Connecticut, United States. The proposed study will use a randomized clinical t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05286892" }, { "text": "Safety and Efficacy of Fecal Microbiota Transplantation on Cognitive Function in T1DM — RECRUITING, NA. Interventions: fecal microbiota transplantation, Placebo. Locations: Changsha, Hunan, China. This study is a prospective, single-center, parallel-design,1:1 randomized controlled trial with triple blindi...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06496412" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-29:research-watch", "slug": "2026-09-29-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-29T08:00:00.000Z", "updatedAt": "2026-09-29T10:17:01.689Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-f3a19a041e5bbad4.webp", "alt": "Female scientist working with test tubes and microscope in a laboratory.", "credit": "Gustavo Fring (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/woman-in-laboratory-8770723/", "__contentHash": "ca6cf6ebb2f46a1b4aec8156a26fc9c40d5b2ce49a82153d90b2ebd1ab19e63a", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-29" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-28:daily-type-1-diabetes-briefing", "slug": "2026-09-28-daily-type-1-diabetes-briefing", "title": "September 28, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-28T08:00:00.000Z", "updatedAt": "2026-09-28T10:17:02.097Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-3744adb6cfe611d8.webp", "alt": "Close-up of a researcher using tweezers to work with a petri dish in a lab setting.", "credit": "www.kaboompics.com (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/hands-of-a-person-in-gloves-holding-a-petri-dish-and-tongs-8539141/", "__contentHash": "d958bfee99f36d17489776b2399fd60a3813307af16012c7ddf74e122b2c5754", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 28, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: Tele-diabetes Remote System. Locations: Ramat Gan, Israel. The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on ma...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07828106" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 28, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-28:device-safety-watch", "slug": "2026-09-28-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-28T08:00:00.000Z", "updatedAt": "2026-09-28T10:17:02.097Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-signal-6e71f5b184ae89a4.webp", "alt": "Accu-chek blood glucose test strips", "credit": "Karl101 (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=32279438", "__contentHash": "53678475d2ba450a8ba4be610cf0df1c8face24f04e7a9e49b9af954a9bbc6e1", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-28:how-type1cure-labels-evidence", "slug": "2026-09-28-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-28T08:00:00.000Z", "updatedAt": "2026-09-28T10:17:02.097Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/lifestyle-pmid-42497120.webp", "alt": "Elderly man in a gym stretching with a fitness coach, promoting a healthy lifestyle.", "credit": "Kampus Production (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/man-wearing-sportswear-stretching-his-legs-6922122/", "__contentHash": "88840dc9e0a3a37e99f1f1db6570f2b29b0b38f452db90fc2313ae284200eed0", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-28:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-28-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-28T08:00:00.000Z", "updatedAt": "2026-09-28T10:17:02.097Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42669005.webp", "alt": "Nurse attends to patient with doctor observing", "credit": "The New York Public Library (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/nurse-attends-to-patient-with-doctor-observing-tGlt683cXL0", "__contentHash": "c7164927f499af4746f87e6ff85a0bca5628cae9bb12919a5afb84c291971536", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "clinicaltrials:NCT03528226", "clinicaltrials:NCT05498974", "clinicaltrials:NCT06217302", "clinicaltrials:NCT07258758", "clinicaltrials:NCT07195045", "clinicaltrials:NCT06803446", "clinicaltrials:NCT06966427", "clinicaltrials:NCT05767450" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Exercise Training and Endothelial Function in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT03528226", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-14" }, { "title": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05498974", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease", "url": "https://clinicaltrials.gov/study/NCT06217302", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-24" }, { "title": "Diabetes Intervention Involving Person-centred Nutritional Education", "url": "https://clinicaltrials.gov/study/NCT07258758", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-12" }, { "title": "Thai PainPREDICT Validation Study", "url": "https://clinicaltrials.gov/study/NCT07195045", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-03" }, { "title": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06803446", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-04" }, { "title": "Prospective Evaluation of a Dose Guidance System for People With Diabetes Initiating Basal Insulin or Using Insulin Injections", "url": "https://clinicaltrials.gov/study/NCT06966427", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-11" }, { "title": "Intervention on New Onset-T1D Children", "url": "https://clinicaltrials.gov/study/NCT05767450", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-02" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: Tele-diabetes Remote System. Locations: Ramat Gan, Israel. The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on ma...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07828106" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Exercise Training and Endothelial Function in Type 1 Diabetes — RECRUITING, NA. Interventions: Exercise Training Procedure, Normal life procedure. Locations: Lille, France. Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03528226" }, { "text": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes — RECRUITING. Interventions: Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center. Locations: Lanzhou, Gansu, China | Shenzhen, Guangdong, China | Haikou, Hainan, Chin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05498974" }, { "text": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — RECRUITING, PHASE3. Interventions: Sotagliflozin, Placebo. Locations: Stanford, California, United States | Aurora, Colorado, United States | Orlando, Florida, United States. Powerful new drugs that can prevent or delay...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06217302" }, { "text": "Diabetes Intervention Involving Person-centred Nutritional Education — RECRUITING, NA. Interventions: Dietary intervention. Locations: Enköping, Uppland, Sweden. The overall objective for this project is to evaluate the effects of a person-centred education intervention to promote a health...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07258758" }, { "text": "Thai PainPREDICT Validation Study — RECRUITING, NA. Interventions: Thai PainPREDICT Questionnaire and Mobile Application. Locations: Pathum Wan, Bangkok, Thailand. Painful diabetic neuropathy (PDN) is one of the most common and disabling complications of...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07195045" }, { "text": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes — RECRUITING, NA. Interventions: physical test. Locations: Loos, Nord, France. Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06803446" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-28:research-watch", "slug": "2026-09-28-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-28T08:00:00.000Z", "updatedAt": "2026-09-28T10:17:02.097Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42394369.webp", "alt": "Scientific Research Institute of Lung Diseases of the Ministry of Health of the Republic of Azerbaijan", "credit": "ChanisCaucasi (Openverse / BY 4.0)", "license": "Openverse BY 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=181988352", "__contentHash": "5ab7e249e78940a95fc24fb3d60174b1366bc49cb29229eb8a822582868a6012", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-28" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-27:daily-type-1-diabetes-briefing", "slug": "2026-09-27-daily-type-1-diabetes-briefing", "title": "September 27, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-27T08:00:00.000Z", "updatedAt": "2026-09-27T10:17:01.724Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-6909b3591b9259ab.webp", "alt": "Researchers in a lab examining test tubes with colored liquids for experiments.", "credit": "cottonbro studio (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/people-holding-clear-glass-tubes-with-colored-liquid-8666427/", "__contentHash": "6a7c8f67e3761540042139dbc4df79dc47512befc92edd108646b0f03c467091", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 27, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: Tele-diabetes Remote System. Locations: Ramat Gan, Israel. The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on ma...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07828106" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 27, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-27:device-safety-watch", "slug": "2026-09-27-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-27T08:00:00.000Z", "updatedAt": "2026-09-27T10:17:01.724Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-signal-1345af509f6a2ec0.webp", "alt": "Blood glucose test strip2", "credit": "Krzysztof P. Jasiutowicz (talk) (Uploads). (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=47199464", "__contentHash": "b1255405f6a4ce27196d12337667edee4514aa4a5ea3cf0e0118e4e1eaa57b7a", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-27:how-type1cure-labels-evidence", "slug": "2026-09-27-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-27T08:00:00.000Z", "updatedAt": "2026-09-27T10:17:01.724Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42738899.webp", "alt": "Close-up of a syringe and medical gloves on a flat surface, showcasing healthcare tools.", "credit": "Roger Brown (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/syringe-on-latex-gloves-5664737/", "__contentHash": "41b81b68227cc9f8bce08d9c4b77ae0aaf45b0ca5ba8e299b81874737c0626a2", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-27:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-27-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-27T08:00:00.000Z", "updatedAt": "2026-09-27T10:17:01.724Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42389685.webp", "alt": "Medical professional wearing gloves preparing patient for blood draw using a tourniquet.", "credit": "Lucas Oliveira (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-medical-professional-wearing-latex-gloves-holding-a-person-s-hand-4680228/", "__contentHash": "5d11b8d2734f322303a58d6287c8df88e8a37fc854a6c2f9b69251870faea4f8", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "clinicaltrials:NCT03528226", "clinicaltrials:NCT05498974", "clinicaltrials:NCT06217302", "clinicaltrials:NCT07258758", "clinicaltrials:NCT07195045", "clinicaltrials:NCT06803446", "clinicaltrials:NCT06966427", "clinicaltrials:NCT05767450" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Exercise Training and Endothelial Function in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT03528226", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-14" }, { "title": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05498974", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease", "url": "https://clinicaltrials.gov/study/NCT06217302", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-24" }, { "title": "Diabetes Intervention Involving Person-centred Nutritional Education", "url": "https://clinicaltrials.gov/study/NCT07258758", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-12" }, { "title": "Thai PainPREDICT Validation Study", "url": "https://clinicaltrials.gov/study/NCT07195045", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-03" }, { "title": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06803446", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-04" }, { "title": "Prospective Evaluation of a Dose Guidance System for People With Diabetes Initiating Basal Insulin or Using Insulin Injections", "url": "https://clinicaltrials.gov/study/NCT06966427", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-11" }, { "title": "Intervention on New Onset-T1D Children", "url": "https://clinicaltrials.gov/study/NCT05767450", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-02" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: Tele-diabetes Remote System. Locations: Ramat Gan, Israel. The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on ma...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07828106" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Exercise Training and Endothelial Function in Type 1 Diabetes — RECRUITING, NA. Interventions: Exercise Training Procedure, Normal life procedure. Locations: Lille, France. Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03528226" }, { "text": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes — RECRUITING. Interventions: Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center. Locations: Lanzhou, Gansu, China | Shenzhen, Guangdong, China | Haikou, Hainan, Chin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05498974" }, { "text": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — RECRUITING, PHASE3. Interventions: Sotagliflozin, Placebo. Locations: Stanford, California, United States | Aurora, Colorado, United States | Orlando, Florida, United States. Powerful new drugs that can prevent or delay...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06217302" }, { "text": "Diabetes Intervention Involving Person-centred Nutritional Education — RECRUITING, NA. Interventions: Dietary intervention. Locations: Enköping, Uppland, Sweden. The overall objective for this project is to evaluate the effects of a person-centred education intervention to promote a health...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07258758" }, { "text": "Thai PainPREDICT Validation Study — RECRUITING, NA. Interventions: Thai PainPREDICT Questionnaire and Mobile Application. Locations: Pathum Wan, Bangkok, Thailand. Painful diabetic neuropathy (PDN) is one of the most common and disabling complications of...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07195045" }, { "text": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes — RECRUITING, NA. Interventions: physical test. Locations: Loos, Nord, France. Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06803446" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-27:research-watch", "slug": "2026-09-27-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-27T08:00:00.000Z", "updatedAt": "2026-09-27T10:17:01.724Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-a938a5f89397b2c3.webp", "alt": "Researchers using a microscope and taking notes in a modern lab.", "credit": "Gustavo Fring (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/man-medical-practitioner-using-a-microscope-8770715/", "__contentHash": "f7ac14d8e748efb9611d1a7fad83268df7a0bfbcc574825bd9bc3069cbfbd0b9", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-27" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-26:daily-type-1-diabetes-briefing", "slug": "2026-09-26-daily-type-1-diabetes-briefing", "title": "September 26, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-26T08:00:00.000Z", "updatedAt": "2026-09-26T10:17:01.827Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42505354.webp", "alt": "Laboratory scientist conducts an experiment with a Rotary evaporator", "credit": "National Eye Institute (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=46965738", "__contentHash": "37a264b9d7aac2e8038921a60feea6dff4e302dd40a1267b480ff675bbccf4f9", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 26, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: Tele-diabetes Remote System. Locations: Ramat Gan, Israel. The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on ma...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07828106" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 26, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-26:device-safety-watch", "slug": "2026-09-26-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-26T08:00:00.000Z", "updatedAt": "2026-09-26T10:17:01.827Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42452989.webp", "alt": "person using disposable syringe put specimen on blue and white glucose meter", "credit": "Matt C (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/person-using-disposable-syringe-put-specimen-on-blue-and-white-glucose-meter-bRjpGjwmae8", "__contentHash": "1a0f3d387999825c84cc5b792e16c2ef8f8361fb9fddfce8de53592613e58081", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-26:how-type1cure-labels-evidence", "slug": "2026-09-26-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-26T08:00:00.000Z", "updatedAt": "2026-09-26T10:17:01.827Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42764374.webp", "alt": "Flat lay image of healthcare essentials including a blood pressure monitor, pills, and eyeglasses on a white surface.", "credit": "Yaroslav Shuraev (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/medicines-and-digital-blood-pressure-monitor-on-white-fabric-8088858/", "__contentHash": "2cb81596f51fcd5a99734be470c1735a85a7a0d0dec2f418424c98255f1b674f", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-26:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-26-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-26T08:00:00.000Z", "updatedAt": "2026-09-26T10:17:01.827Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42443623.webp", "alt": "A patient is reflected in a sphygmomanometer during a medical appointment, highlighting the focus on healthcare.", "credit": "Los Muertos Crew (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/reflection-of-a-patient-getting-his-blood-pressure-8460087/", "__contentHash": "6a02886ca31a626e4360edb8ff862895e09367038909a157af6034b235b93152", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07828106", "clinicaltrials:NCT07038473", "clinicaltrials:NCT03528226", "clinicaltrials:NCT05498974", "clinicaltrials:NCT06217302", "clinicaltrials:NCT07258758", "clinicaltrials:NCT07195045", "clinicaltrials:NCT06803446", "clinicaltrials:NCT06966427", "clinicaltrials:NCT05767450" ], "sources": [ { "title": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07828106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-18" }, { "title": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF)", "url": "https://clinicaltrials.gov/study/NCT07038473", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-19" }, { "title": "Exercise Training and Endothelial Function in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT03528226", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-14" }, { "title": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05498974", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease", "url": "https://clinicaltrials.gov/study/NCT06217302", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-24" }, { "title": "Diabetes Intervention Involving Person-centred Nutritional Education", "url": "https://clinicaltrials.gov/study/NCT07258758", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-12" }, { "title": "Thai PainPREDICT Validation Study", "url": "https://clinicaltrials.gov/study/NCT07195045", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-03" }, { "title": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06803446", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-04" }, { "title": "Prospective Evaluation of a Dose Guidance System for People With Diabetes Initiating Basal Insulin or Using Insulin Injections", "url": "https://clinicaltrials.gov/study/NCT06966427", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-11" }, { "title": "Intervention on New Onset-T1D Children", "url": "https://clinicaltrials.gov/study/NCT05767450", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-02" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Feasibility and Effectiveness of Tele-diabetes Remote System on Glycemic Control and Quality of Life of Children and Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: Tele-diabetes Remote System. Locations: Ramat Gan, Israel. The goal of this clinical trial is to examine the feasibility and effectiveness of a tele-diabetes remote monitoring system on ma...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07828106" }, { "text": "Early Detection of Type 1 Diabetes in First Degree Relatives of Type 1 Diabetes Patients (DETECT T1D GULF) — RECRUITING, NA. Interventions: Investigational Procedure. Locations: Kuwait City, Al Asimah / Capital Governorate, Kuwait | Dammam, Eastern Province, Saudi Arabia | Jeddah, Mecca Region, Saudi Arabia. The aim of this re...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07038473" }, { "text": "Exercise Training and Endothelial Function in Type 1 Diabetes — RECRUITING, NA. Interventions: Exercise Training Procedure, Normal life procedure. Locations: Lille, France. Endothelial dysfunction and vasoreactivity disorders are early subclinical complications of type 1 diabetes (T...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03528226" }, { "text": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes — RECRUITING. Interventions: Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center. Locations: Lanzhou, Gansu, China | Shenzhen, Guangdong, China | Haikou, Hainan, Chin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05498974" }, { "text": "Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease — RECRUITING, PHASE3. Interventions: Sotagliflozin, Placebo. Locations: Stanford, California, United States | Aurora, Colorado, United States | Orlando, Florida, United States. Powerful new drugs that can prevent or delay...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06217302" }, { "text": "Diabetes Intervention Involving Person-centred Nutritional Education — RECRUITING, NA. Interventions: Dietary intervention. Locations: Enköping, Uppland, Sweden. The overall objective for this project is to evaluate the effects of a person-centred education intervention to promote a health...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07258758" }, { "text": "Thai PainPREDICT Validation Study — RECRUITING, NA. Interventions: Thai PainPREDICT Questionnaire and Mobile Application. Locations: Pathum Wan, Bangkok, Thailand. Painful diabetic neuropathy (PDN) is one of the most common and disabling complications of...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07195045" }, { "text": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes — RECRUITING, NA. Interventions: physical test. Locations: Loos, Nord, France. Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06803446" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-26:research-watch", "slug": "2026-09-26-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-26T08:00:00.000Z", "updatedAt": "2026-09-26T10:17:01.827Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-bb3fe49bc8c47870.webp", "alt": "A female scientist in a lab coat examines samples under a microscope for research.", "credit": "Edward Jenner (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/female-laboratory-scientist-looking-at-a-microscope-4031525/", "__contentHash": "71a29fdc20b86378abf29e6d7f171d9c5750e668c833376feac5b77e821193d4", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-26" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-25:daily-type-1-diabetes-briefing", "slug": "2026-09-25-daily-type-1-diabetes-briefing", "title": "September 25, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-25T08:00:00.000Z", "updatedAt": "2026-09-25T10:17:01.378Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42789342.webp", "alt": "File:West Nile Vaccine Research in BSL-3 Lab.jpg", "credit": "NIAID (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=37910755", "__contentHash": "0212930110b920103d38a1aeba0163afdf783cb2a537ecbab7df9cfabe13e846", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT04786262", "clinicaltrials:NCT05414409", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04786262", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-01" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 25, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes — RECRUITING, PHASE3. Interventions: VX-880, VX-017. Locations: Duarte, California, United States | San Francisco, California, United States | Miami, Florida, United States. This study will evaluate the safety, tolerabili...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04786262" }, { "text": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action — RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for comp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05414409" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 25, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-25:device-safety-watch", "slug": "2026-09-25-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-25T08:00:00.000Z", "updatedAt": "2026-09-25T10:17:01.378Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42863663.webp", "alt": "A blue insulin pen rests on a white surface", "credit": "Haberdoedas (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/a-blue-insulin-pen-rests-on-a-white-surface-NiXMv9iFN1c", "__contentHash": "f4d4dfaaf93a2e81c76b9150a2aa6a81826a209952c343e1516af867119dca7a", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-25:how-type1cure-labels-evidence", "slug": "2026-09-25-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-25T08:00:00.000Z", "updatedAt": "2026-09-25T10:17:01.378Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42803858.webp", "alt": "the word mental health spelled with scrabbles next to a green leaf", "credit": "Total Shape (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/the-word-mental-health-spelled-with-scrabbles-next-to-a-green-leaf-Ianw4RdVuoo", "__contentHash": "b3be6e1c67782a853a56f34c8b2e1c61c83eb89212a5e4916fc08641b9a30a6e", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT04786262", "clinicaltrials:NCT05414409", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04786262", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-01" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-25:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-25-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-25T08:00:00.000Z", "updatedAt": "2026-09-25T10:17:01.378Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42792728.webp", "alt": "A modern hospital room featuring advanced medical equipment with digital displays.", "credit": "Keysi Estrada (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/futuristic-hospital-room-with-medical-equipment-32026163/", "__contentHash": "a31a6d35969ae3f707ba6584652829ea6d964187d3696a13a2aaf93deba7529b", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT04786262", "clinicaltrials:NCT05414409", "clinicaltrials:NCT06852950", "clinicaltrials:NCT03746769", "clinicaltrials:NCT06609356", "clinicaltrials:NCT07179471", "clinicaltrials:NCT06875167", "clinicaltrials:NCT05957055", "clinicaltrials:NCT05678543" ], "sources": [ { "title": "A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04786262", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-01" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge", "url": "https://clinicaltrials.gov/study/NCT06852950", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-05" }, { "title": "Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes", "url": "https://clinicaltrials.gov/study/NCT03746769", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-23" }, { "title": "Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06609356", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-23" }, { "title": "Fake Carbs Practice With AID System - MiniMed 780G in Children and Adolescents With T1D.", "url": "https://clinicaltrials.gov/study/NCT07179471", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-17" }, { "title": "Semi-closed Loop Automated Insulin Therapy in the Pediatric Population Aged 2-6 Years With Type 1 Diabetes: Impact on Quality of Life and Glycemic Control", "url": "https://clinicaltrials.gov/study/NCT06875167", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-04-20" }, { "title": "Lisdexamphetamine Vs Methylphenidate for Pediatric Patients with ADHD and Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05957055", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-11-29" }, { "title": "Danish Diabetes Birth Registry 2", "url": "https://clinicaltrials.gov/study/NCT05678543", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-04-12" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "A Safety, Tolerability, and Efficacy Study of VX-880 and VX-017 in Participants With Type 1 Diabetes — RECRUITING, PHASE3. Interventions: VX-880, VX-017. Locations: Duarte, California, United States | San Francisco, California, United States | Miami, Florida, United States. This study will evaluate the safety, tolerabili...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04786262" }, { "text": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action — RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for comp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05414409" }, { "text": "Continuous Glucose Monitoring for Outpatient Diabetes Management After Hospital Discharge — RECRUITING, NA. Interventions: Libre 3 Plus Continuous Glucose Monitor, Dexcom G7 Continuous Glucose Monitor. Locations: Nashville, Tennessee, United States. This study aims to improve patient awareness of the utility o...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06852950" }, { "text": "Improving Islet Transplantation Outcomes With Gastrin for Type I Diabetes — RECRUITING, PHASE1, PHASE2. Interventions: Allogenic Human Islet Cells, Gastrin 17. Locations: Duarte, California, United States. This clinical study will evaluate the safety and effectiveness of Gastrin treatment with...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03746769" }, { "text": "Cardiometabolic Benefit of Reducing Iatrogenic Hyperinsulinemia Using Insulin Adjunctive Therapy in Type 1 Diabetes — RECRUITING, EARLY_PHASE1. Interventions: Study Visit 1, Placebo, Study Visit 2. Locations: Nashville, Tennessee, United States. This study aims to understand the heart and blood sugar health benefits of using an adjunct...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06609356" }, { "text": "Fake Carbs Practice With AID System - MiniMed 780G in Children and Adolescents With T1D. — RECRUITING. Locations: Athens, Attica, Greece | Athens, Attica, Greece | Athens, Attica, Greece. Hybrid Closed Loop (HCL) systems, such as the MiniMed 780G, have significantly improved glycemic outcomes in Type 1 Diabet...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07179471" }, { "text": "Semi-closed Loop Automated Insulin Therapy in the Pediatric Population Aged 2-6 Years With Type 1 Diabetes: Impact on Quality of Life and Glycemic Control — RECRUITING. Locations: Nice, France, France. The incidence of type 1 diabetes is increasing, with an incidence of +4% per year in France today. The treatment for type 1 diabetes is insulin therapy. In recent years, new...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06875167" }, { "text": "Lisdexamphetamine Vs Methylphenidate for Pediatric Patients with ADHD and Type 1 Diabetes — RECRUITING, PHASE2. Interventions: parental training in behavior management, Lisdexamfetamine, Methylphenidate. Locations: Lodz, Łódź Voivodeship, Poland. This clinical trial aims to evaluate the safety and effectivenes...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05957055" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-25:research-watch", "slug": "2026-09-25-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-25T08:00:00.000Z", "updatedAt": "2026-09-25T10:17:01.378Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-f98cb2d444995e0d.webp", "alt": "Limbal epithelium. Cells. SEM-BSE", "credit": "Ivan A. Novikov (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=44833871", "__contentHash": "9d42427a6d049a8f9defe7a14ce4f94db827edb8818c428ecceddc3a6cb01502", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-25" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-24:daily-type-1-diabetes-briefing", "slug": "2026-09-24-daily-type-1-diabetes-briefing", "title": "September 24, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-24T08:00:00.000Z", "updatedAt": "2026-09-24T10:17:01.654Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-3ad2138d50172ba6.webp", "alt": "File:Glasgow clinical research facility.png", "credit": "Robertson Centre for Biostatistics (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=15778145", "__contentHash": "d08b4fe138099da7dd1296504d18cf314045ace9c0d3be2159304095704d6cce", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT06739811", "clinicaltrials:NCT07804849", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07726680", "openfda-device-recall:221103", "clinicaltrials:NCT05849753", "openfda-device-recall:221053", "openfda-device-recall:220614" ], "sources": [ { "title": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)", "url": "https://clinicaltrials.gov/study/NCT06739811", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07726680", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-24" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05849753", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-20" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 24, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347) — RECRUITING, NA. Interventions: Implantable Insulin Pump System. Locations: Bordeaux, France, France | Corbeil-Essonnes, France, France | Lille, France, France. The purpose of this study is to evaluate the clinical perfo...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06739811" }, { "text": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes — RECRUITING, PHASE2, PHASE3. Interventions: Verapamil oral, Placebo. Locations: Cairo, Egypt. Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verap...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07804849" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes — RECRUITING, NA. Interventions: GlycoQuest Digital Therapeutic, Enhanced Digital Psychoeducation. Locations: Lahore, Punjab Province, Pakistan. Type 1 diabetes diagnosed in childhood requires rapid acquisition of complex...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07726680" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 24, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-24:device-safety-watch", "slug": "2026-09-24-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-24T08:00:00.000Z", "updatedAt": "2026-09-24T10:17:01.654Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42438052.webp", "alt": "Bottle of dextrotabs for glucose and glucose", "credit": "Annie Spratt (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/bottle-of-dextrotabs-for-glucose-and-glucose-GEo_nRxJBEA", "__contentHash": "e79bd15629386e93e8e96154c619fa015125447861e3eee3ee341b345bccf794", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-24:how-type1cure-labels-evidence", "slug": "2026-09-24-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-24T08:00:00.000Z", "updatedAt": "2026-09-24T10:17:01.654Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42441154.webp", "alt": "Adult female using a medical weighing scale in a healthcare setting.", "credit": "RDNE Stock project (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-person-on-using-a-weighing-scale-6129508/", "__contentHash": "9f34487e4a933fa5cc78ef7ffb8d65a7fa6d05b65c531a53c9d0a654e6374ae5", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT06739811", "clinicaltrials:NCT07804849", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07726680" ], "sources": [ { "title": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)", "url": "https://clinicaltrials.gov/study/NCT06739811", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07726680", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-24" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-24:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-24-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-24T08:00:00.000Z", "updatedAt": "2026-09-24T10:17:01.654Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42475657.webp", "alt": "A doctor performs an eye examination on a patient in a clinical setting.", "credit": "Imad Clicks (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-doctor-examining-patients-eye-14558556/", "__contentHash": "8926178d221ccba13c9391fb75fc6fbc76723aaf26d7ba56243848b7b5e0b564", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06739811", "clinicaltrials:NCT07804849", "clinicaltrials:NCT07726680", "clinicaltrials:NCT05849753", "clinicaltrials:NCT07638345", "clinicaltrials:NCT04334707", "clinicaltrials:NCT06964087", "clinicaltrials:NCT07287943", "clinicaltrials:NCT05923632", "clinicaltrials:NCT06876207" ], "sources": [ { "title": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347)", "url": "https://clinicaltrials.gov/study/NCT06739811", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-22" }, { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07726680", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-24" }, { "title": "Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05849753", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-20" }, { "title": "DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions", "url": "https://clinicaltrials.gov/study/NCT07638345", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-23" }, { "title": "Kidney Precision Medicine Project", "url": "https://clinicaltrials.gov/study/NCT04334707", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-14" }, { "title": "Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT06964087", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-06" }, { "title": "To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes.", "url": "https://clinicaltrials.gov/study/NCT07287943", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-18" }, { "title": "The Effect Of Model-Based Dıgıtal Game On Metabolıc Control, Self-Effıcıency And Qualıty Of Lıfe In Chıldren Wıth Type 1 Dıabetes", "url": "https://clinicaltrials.gov/study/NCT05923632", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-11" }, { "title": "Real-world Study on the Effectiveness and Safety of Control-IQ Technology in Teenagers With Type 1 Diabetes Engaging in Regular Physical Activity", "url": "https://clinicaltrials.gov/study/NCT06876207", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-06-25" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Clinical Evaluation of the Medtronic Implantable Insulin Pump System (MIIPS 2020) in Adult Subjects With Type 1 Diabetes (CIP347) — RECRUITING, NA. Interventions: Implantable Insulin Pump System. Locations: Bordeaux, France, France | Corbeil-Essonnes, France, France | Lille, France, France. The purpose of this study is to evaluate the clinical perfo...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06739811" }, { "text": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes — RECRUITING, PHASE2, PHASE3. Interventions: Verapamil oral, Placebo. Locations: Cairo, Egypt. Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verap...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07804849" }, { "text": "GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes — RECRUITING, NA. Interventions: GlycoQuest Digital Therapeutic, Enhanced Digital Psychoeducation. Locations: Lahore, Punjab Province, Pakistan. Type 1 diabetes diagnosed in childhood requires rapid acquisition of complex...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07726680" }, { "text": "Breaking Disparities in Access to Advanced Diabetes Technologies in Children With Type 1 Diabetes — RECRUITING. Interventions: Advanced artificial pancreas closed-loop technology. Locations: Jacksonville, Florida, United States | Orlando, Florida, United States. 50 children/adolescents (ages 6 to \\<18yrs) with T1D in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05849753" }, { "text": "DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions — RECRUITING, NA. Interventions: Adhera Caring Digital Program-Obesity (ACDP-O). Locations: Seville, Spain. This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07638345" }, { "text": "Kidney Precision Medicine Project — RECRUITING. Interventions: Kidney Biopsy, MRI, Retina Scan. Locations: Tucson, Arizona, United States | New Haven, Connecticut, United States | Chicago, Illinois, United States. Acute kidney injury (AKI) and chronic kid...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04334707" }, { "text": "Pharmacokinetic and Early Efficacy of OPT101 in Patients With Type 1 Diabetes Mellitus — RECRUITING, PHASE2. Interventions: OPT101, OPT101 Placebo to Match (PTM). Locations: Birmingham, Alabama, United States | Walnut Creek, California, United States | Aurora, Colorado, United States. This study will examin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06964087" }, { "text": "To Study the Efficacy and Safety of Medtronic 780G Insulin Pump in People With Gastroparesis and Type 1 Diabetes. — RECRUITING, NA. Interventions: Medtronic 780G AID. Locations: Indianapolis, Indiana, United States. The goal of this clinical trial is to evaluate the efficacy and safety of Medtronic 780G automated insulin delivery sys...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07287943" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-24:research-watch", "slug": "2026-09-24-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-24T08:00:00.000Z", "updatedAt": "2026-09-24T10:17:01.654Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42674453.webp", "alt": "Army scientists energize battery research", "credit": "U.S. Army Combat Capabilities Development Command (Openverse / BY-SA 2.0)", "license": "Openverse BY-SA 2.0", "sourceUrl": "https://www.flickr.com/photos/34402227@N03/7222825892", "__contentHash": "d2512e01d12ccc211635e76aa337ed5581fdaf70b4d9952a0b0c5d01ce2e349c", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-24" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-23:daily-type-1-diabetes-briefing", "slug": "2026-09-23-daily-type-1-diabetes-briefing", "title": "September 23, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-23T08:00:00.000Z", "updatedAt": "2026-09-23T10:17:01.115Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-376bd88b556e85d9.webp", "alt": "Medical Research Lab, Brown University", "credit": "Giddy75 (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=174079538", "__contentHash": "f8d8b50bb15863f4438c8ff96164de367ec509c56c87a20203887559de325857", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT05414409", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 23, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action — RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for comp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05414409" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 23, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-23:device-safety-watch", "slug": "2026-09-23-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-23T08:00:00.000Z", "updatedAt": "2026-09-23T10:17:01.115Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42490580.webp", "alt": "File:Glucose test.JPG", "credit": "Erik1980 (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=1667907", "__contentHash": "36729cdd62d0ba4e04ff73890c87e5dd52f1f8f189b82427aa3b30110f28d73d", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-23:how-type1cure-labels-evidence", "slug": "2026-09-23-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-23T08:00:00.000Z", "updatedAt": "2026-09-23T10:17:01.115Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42409021.webp", "alt": "Syringe and vaccine vials arranged on gray surface, symbolizing healthcare and immunization.", "credit": "Thirdman (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/four-covid19-vials-and-an-injection-5922099/", "__contentHash": "9743910bd006cc32cfa25609b4fdba2c00de272623a8ba4b2df433a991008782", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT05414409", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-23:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-23-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-23T08:00:00.000Z", "updatedAt": "2026-09-23T10:17:01.115Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42525131.webp", "alt": "Nurse uses digital tablet for patient consultation and diagnosis in a clinical setting.", "credit": "Cedric Fauntleroy (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/man-in-gray-shirt-holding-a-tablet-computer-4269933/", "__contentHash": "bad88234fd21c73a1b9bb8c8991493c6ce24cdf051ea66446a04dfe21788ce92", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT05414409", "clinicaltrials:NCT05498116", "clinicaltrials:NCT05505669", "clinicaltrials:NCT07621445", "clinicaltrials:NCT07062887", "clinicaltrials:NCT06646107", "clinicaltrials:NCT05286892", "clinicaltrials:NCT07050888", "clinicaltrials:NCT07021456" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action", "url": "https://clinicaltrials.gov/study/NCT05414409", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-21" }, { "title": "Effect of Montelukast on Kidney and Vascular Function in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05498116", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-30" }, { "title": "Circulating Biomarkers in the Development of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05505669", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-24" }, { "title": "Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study", "url": "https://clinicaltrials.gov/study/NCT07621445", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-02" }, { "title": "Digital Mindfulness for Young Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07062887", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-09" }, { "title": "Adherence to Mediterranean Diet in Type 1 Diabetes Initiating Minimed 780G: Glucose Metrics vs Insulin Metrics, is There a Difference", "url": "https://clinicaltrials.gov/study/NCT06646107", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-11-19" }, { "title": "Diabetes Learning in Virtual Environments Just in Time for Community Reentry", "url": "https://clinicaltrials.gov/study/NCT05286892", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-28" }, { "title": "Effect of Inulin Supplementation on Glycaemic Control and Immunological Parameters in Type 1 Diabetes (2024)", "url": "https://clinicaltrials.gov/study/NCT07050888", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-03" }, { "title": "Impact of Dietary Knowledge Related to Functional Insulin Therapy in Type 1 Diabetes on the Risk of Eating Disorders", "url": "https://clinicaltrials.gov/study/NCT07021456", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-06-15" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "The Gut Microbiome in Type 1 Diabetes and Mechanism of Metformin Action — RECRUITING, PHASE2. Interventions: Metformin. Locations: Indianapolis, Indiana, United States. Ovwerweight and obesity prevalence in persons with T1D has increased, which further complicates management and risk for comp...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05414409" }, { "text": "Effect of Montelukast on Kidney and Vascular Function in Type 1 Diabetes — RECRUITING, PHASE4. Interventions: Montelukast, Placebo. Locations: Aurora, Colorado, United States. Kidney disease is a common problem among people with type 1 diabetes and can lead to disability, dialysis, and early d...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05498116" }, { "text": "Circulating Biomarkers in the Development of Type 1 Diabetes — RECRUITING. Interventions: One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit.. Locations: Duarte, California, Un...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05505669" }, { "text": "Genetic Risk Score of Type 1 Diabetes Mellitus for Progression to Insulin in Diabetic Patients Lack of Predictive Value: a Multicenter Nested Case-control Study — RECRUITING. Locations: Changsha, Hunan, China. The goal of this observational study is to evaluate the predictive value of the genetic risk score for type 1 diabetes in the progression to insulin deficiency in diabetic...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07621445" }, { "text": "Digital Mindfulness for Young Adults With Type 1 Diabetes — RECRUITING, NA. Interventions: Mindfulness app. Locations: New Haven, Connecticut, United States. The purpose of this research study is to test a mindfulness app called Calm Health among young adults with type 1 diabete...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07062887" }, { "text": "Adherence to Mediterranean Diet in Type 1 Diabetes Initiating Minimed 780G: Glucose Metrics vs Insulin Metrics, is There a Difference — RECRUITING. Interventions: MInimed 780G. Locations: Chaïdári, Greece. In this observaltional study, 240 patients aged \\>12 years old with T1DM who are on multiple daily injections or insulin pump and are scheduled to st...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06646107" }, { "text": "Diabetes Learning in Virtual Environments Just in Time for Community Reentry — RECRUITING, NA. Interventions: Diabetes LIVE JustICE, Enhanced Education. Locations: Storrs, Connecticut, United States | Storrs Mansfield, Connecticut, United States. The proposed study will use a randomized clinical t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05286892" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-23:research-watch", "slug": "2026-09-23-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-23T08:00:00.000Z", "updatedAt": "2026-09-23T10:17:01.115Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42501066.webp", "alt": "Portrait, microscope, laboratory, test tube, scale, burette Fortepan 7166", "credit": "FOTO:Fortepan — ID 7166: Adományozó/Donor: Csontos Péter. archive copy (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=49251249", "__contentHash": "86bb39e70e8e50309df84c5d76e00a275e2ed3d2dc04074c8696d2b4b94ee84b", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-23" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-22:daily-type-1-diabetes-briefing", "slug": "2026-09-22-daily-type-1-diabetes-briefing", "title": "September 22, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-22T08:00:00.000Z", "updatedAt": "2026-09-22T10:17:01.963Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-d42039a261052712.webp", "alt": "Detailed view of a semaglutide injection pen, commonly used for diabetes treatment, on a plain background.", "credit": "Haberdoedas Photography (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/close-up-of-semaglutide-injection-pen-on-surface-32532049/", "__contentHash": "f9a6451779eac1682051d2c6bfe54d04aa7c48ac19382b7b056edad16e9d6dc7", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07142252", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "clinicaltrials:NCT06688331", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT07142252", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody", "url": "https://clinicaltrials.gov/study/NCT06688331", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 22, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus — RECRUITING, PHASE2. Interventions: Rezpegaldesleukin, Placebo. Locations: San Francisco, California, United States | Aurora, Colorado, United States | New Haven, Connecticut, United States. This Phase 2 study is a 2-arm...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07142252" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody — RECRUITING, PHASE2. Interventions: ex vivo expanded CD4+CD25+CD127- regulatory T cells (Tregs), Anti-CD20 (rituximab), Placebo. Locations: Bialystok, Poland | Gdansk, Poland | Katowice, Poland. The main purpose of the s...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06688331" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 22, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-22:device-safety-watch", "slug": "2026-09-22-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-22T08:00:00.000Z", "updatedAt": "2026-09-22T10:17:01.963Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-signal-e22c9e12a8834502.webp", "alt": "Insulin pen in I-Port Advance", "credit": "Marius Vassnes (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=127044966", "__contentHash": "382b439ed7b9d29704d73afdfc4e05991770252a1f4869f343981e21777da70c", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-22:how-type1cure-labels-evidence", "slug": "2026-09-22-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-22T08:00:00.000Z", "updatedAt": "2026-09-22T10:17:01.963Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42601420.webp", "alt": "Detailed close-up of vibrant blue gel capsules symbolizing medical and healthcare treatments.", "credit": "Castorly Stock (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/blue-gel-capsules-on-table-4058107/", "__contentHash": "51001778044806ecd09957701002a4ed0d9de0fedfb7f70048b353fe806f8c99", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT07142252", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "clinicaltrials:NCT06688331" ], "sources": [ { "title": "Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT07142252", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody", "url": "https://clinicaltrials.gov/study/NCT06688331", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-22:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-22-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-22T08:00:00.000Z", "updatedAt": "2026-09-22T10:17:01.963Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42842073.webp", "alt": "A blood bag with a drip chamber hanging in a clinical setting", "credit": "Aman Chaturvedi (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/blood-bag-in-clinical-setting-0ZZo5o00o80", "__contentHash": "ee9b0f46b05a163e626d5b72e356779310da406bcf30059e805f9c58a2a3ab55", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07142252", "clinicaltrials:NCT06688331", "clinicaltrials:NCT07638345", "clinicaltrials:NCT05317455", "clinicaltrials:NCT07292558", "clinicaltrials:NCT06752928", "clinicaltrials:NCT06516614", "clinicaltrials:NCT05203640", "clinicaltrials:NCT02169518" ], "sources": [ { "title": "Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus", "url": "https://clinicaltrials.gov/study/NCT07142252", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody", "url": "https://clinicaltrials.gov/study/NCT06688331", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-17" }, { "title": "DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions", "url": "https://clinicaltrials.gov/study/NCT07638345", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-23" }, { "title": "Regulation of Brain Glucose Metabolism in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05317455", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-09" }, { "title": "Achieving Health in Emerging Adults With Diabetes (AHEAD) Program: A Clinical Trial Designed to Understand if Participation in a Clinical Program Developed Specifically to Support Emerging Adults With Type 1 Diabetes Le...", "url": "https://clinicaltrials.gov/study/NCT07292558", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-12-30" }, { "title": "A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06752928", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-08" }, { "title": "Sleep Coach for Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06516614", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-10-01" }, { "title": "Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05203640", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-08" }, { "title": "Paraoxonase and HDL Qualities in Glycaemia and Inflammation", "url": "https://clinicaltrials.gov/study/NCT02169518", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2023-04-12" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Rezpegaldesleukin (NKTR-358) in New Onset Type 1 Diabetes Mellitus — RECRUITING, PHASE2. Interventions: Rezpegaldesleukin, Placebo. Locations: San Francisco, California, United States | Aurora, Colorado, United States | New Haven, Connecticut, United States. This Phase 2 study is a 2-arm...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07142252" }, { "text": "Treatment of Presymptomatic (Stage 1) Type 1 Diabetes Pediatric Patients With Treg Cell Preparations and Anti-CD20 Antibody — RECRUITING, PHASE2. Interventions: ex vivo expanded CD4+CD25+CD127- regulatory T cells (Tregs), Anti-CD20 (rituximab), Placebo. Locations: Bialystok, Poland | Gdansk, Poland | Katowice, Poland. The main purpose of the s...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06688331" }, { "text": "DASH-Obesity: Explainable AI for Family-Centric Personalized Weight Control in Adolescents and Young Adults With Obesity and Chronic Conditions — RECRUITING, NA. Interventions: Adhera Caring Digital Program-Obesity (ACDP-O). Locations: Seville, Spain. This prospective single-arm feasibility study evaluates the Adhera Caring Digital Program for Obesity (ACDP-O), a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07638345" }, { "text": "Regulation of Brain Glucose Metabolism in Type 1 Diabetes — RECRUITING, EARLY_PHASE1. Interventions: Dichloroacetate. Locations: New Haven, Connecticut, United States. This is a prospective randomized placebo-controlled double-blind crossover pilot study determining the effect o...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05317455" }, { "text": "Achieving Health in Emerging Adults With Diabetes (AHEAD) Program: A Clinical Trial Designed to Understand if Participation in a Clinical Program Developed Specifically to Support Emerging Adults With Type 1 Diabetes Le... — RECRUITING, NA. Interventions: AHEAD Program. Locations: Seattle, Washington, United States. The goal of this study is to determine whether the Achieving Health in Emerging Adults with Diabetes (AHEAD) Program helps eme...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07292558" }, { "text": "A Study Comparing Dexcom Continuous Glucose Monitoring to Point of Care Glucose Testing for the Management of Hospital and Post-Discharge Subjects With Type 1 Diabetes — RECRUITING, NA. Interventions: Dexcom G7 rtCGM, Capillary Blood glucose Testing (POC). Locations: Atlanta, Georgia, United States. This study aims to compare inpatient glycemic control by measuring the percentage of tim...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06752928" }, { "text": "Sleep Coach for Adolescents With Type 1 Diabetes — RECRUITING, NA. Interventions: Sleep Coach, Diabetes Education. Locations: Nashville, Tennessee, United States. The goal of this work is to conduct a randomized trial evaluating the effects of a behavioral intervention...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06516614" }, { "text": "Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes — RECRUITING, NA. Interventions: High repetition (HI), Moderate repetition (MOD). Locations: Edmonton, Alberta, Canada. Regular physical activity has substantial health benefits in people with type 1 diabetes. The fear of...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05203640" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-22:research-watch", "slug": "2026-09-22-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-22T08:00:00.000Z", "updatedAt": "2026-09-22T10:17:01.963Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-2ea7b2158c0ee971.webp", "alt": "A scientist carefully examining samples using a microscope in a modern laboratory setting.", "credit": "Ron Lach (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/woman-using-microscope-9768442/", "__contentHash": "809855b7f919716e18047a121b96693a6b70a2f6208220446052b51703185ea8", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-22" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-21:daily-type-1-diabetes-briefing", "slug": "2026-09-21-daily-type-1-diabetes-briefing", "title": "September 21, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-21T08:00:00.000Z", "updatedAt": "2026-09-21T10:17:01.931Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-5075311ba64ecb87.webp", "alt": "Scientists from South Africa training on mRNA Vaccine Production at the NIAID Vaccine Research Center", "credit": "NIAID (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=139619900", "__contentHash": "c6515051f379fade198bd277e272cfe9a84db151550a7c8649813d38fbb10a79", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07522866", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 21, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Thrive With Type 1 Diabetes 2026 — RECRUITING, NA. Interventions: TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm. Locations: Atlanta, Georgia, United States | Atlanta, Georgia, United States. This study aims to learn whether a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07522866" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 21, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-21:device-safety-watch", "slug": "2026-09-21-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-21T08:00:00.000Z", "updatedAt": "2026-09-21T10:17:01.931Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-yt-p-kbpi0-kt0.webp", "alt": "A yellow medical sensor attached to a person's arm", "credit": "Salahuddin Ahmed (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/a-yellow-medical-sensor-attached-to-a-persons-arm-tIEsUnmLaKY", "__contentHash": "132e802263f9744753cfd4eb5b3da86e782134ad3613c0c08fb5ecd1eb4b5d02", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-21:how-type1cure-labels-evidence", "slug": "2026-09-21-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-21T08:00:00.000Z", "updatedAt": "2026-09-21T10:17:01.931Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-pmid-42626152.webp", "alt": "Colorful vegan salads featuring fresh vegetables in close-up for healthy eating inspiration.", "credit": "Engin Akyurt (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/slices-of-vegetable-in-white-ceramic-bowls-9399987/", "__contentHash": "75739b4406fbf1c8dbb9ace50900878b136eaae44172691fc15431f9cc64d3d7", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07522866", "openfda-device-recall:221103" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-21:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-21-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-21T08:00:00.000Z", "updatedAt": "2026-09-21T10:17:01.931Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-c367f908a4c8ba76.webp", "alt": "Duke Clinical Research Institute, Durham, North Carolina", "credit": "Monumenteer2014camper (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=34659160", "__contentHash": "d5e0753d70698dd56b6063ce12b222aeec60b9b280772780c8f53b533ce0c277", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT07522866", "clinicaltrials:NCT05822609", "clinicaltrials:NCT07386340", "clinicaltrials:NCT06670625", "clinicaltrials:NCT07159282", "clinicaltrials:NCT06984133", "clinicaltrials:NCT06683391", "clinicaltrials:NCT05487534", "clinicaltrials:NCT03463564" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05822609", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-02" }, { "title": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature", "url": "https://clinicaltrials.gov/study/NCT07386340", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-21" }, { "title": "Intensive Dietary and Activity Counselling (IDAC)", "url": "https://clinicaltrials.gov/study/NCT06670625", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-13" }, { "title": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers", "url": "https://clinicaltrials.gov/study/NCT07159282", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-11" }, { "title": "Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06984133", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-22" }, { "title": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06683391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-02-25" }, { "title": "Do \"sugar Swings\" Impact the Brain Function and the Eating Behaviors of People with Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05487534", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-10-09" }, { "title": "Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type 1 Diabetic Patients", "url": "https://clinicaltrials.gov/study/NCT03463564", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2018-03-15" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "Thrive With Type 1 Diabetes 2026 — RECRUITING, NA. Interventions: TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm. Locations: Atlanta, Georgia, United States | Atlanta, Georgia, United States. This study aims to learn whether a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07522866" }, { "text": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Semaglutide, Placebo. Locations: Aurora, Colorado, United States | Seattle, Washington, United States | Spokane, Washington, United States. The primary objective of this study is to de...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05822609" }, { "text": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature — RECRUITING, NA. Interventions: Continuous Glucose Monitoring System. Locations: Escondido, California, United States. A prospective, multicenter evaluation of performance and safety of the Eversense Gemini System with f...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07386340" }, { "text": "Intensive Dietary and Activity Counselling (IDAC) — RECRUITING, NA. Interventions: IDAC+. Locations: Malmö, Sweden. The aim of this intervention study is to investigate if a intensive dietary and physical activity counselling during the first two years of life in childre...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06670625" }, { "text": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers — RECRUITING, PHASE4. Interventions: XWRAP. Locations: Hollywood, Florida, United States. A multicenter, prospective, controlled clinical trial evaluating the efficacy of a single layer placental-based allograft and stand...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07159282" }, { "text": "Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes — RECRUITING, NA. Interventions: Structured education program. Locations: Kuwait City, Sharq, Kuwait. Type 1 diabetes is becoming more common in Kuwaiti and Arab adolescents. Many young people with this condition struggle...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06984133" }, { "text": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes — RECRUITING, NA. Interventions: Oral Carbohydrate (CHO) Administration for Hypoglycemia Prevention and Treatment. Locations: Montreal, Quebec, Canada | Montreal, Quebec, Canada. The REMODAL trial is a randomized crossove...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06683391" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-21:research-watch", "slug": "2026-09-21-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-21T08:00:00.000Z", "updatedAt": "2026-09-21T10:17:01.931Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-a60918a01143431c.webp", "alt": "Detailed view of a scientist operating a microscope in a laboratory setting.", "credit": "Tima Miroshnichenko (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-white-microscope-9574397/", "__contentHash": "2f8b66672ea82c524cd9b3393214254ac20959d0cb9a7c8e1099e136a63fcd83", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-21" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-20:daily-type-1-diabetes-briefing", "slug": "2026-09-20-daily-type-1-diabetes-briefing", "title": "September 20, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-20T08:00:00.000Z", "updatedAt": "2026-09-20T10:17:01.251Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-54d0f6b5502fe6dc.webp", "alt": "Naval Medical Research Center labs support Operation United Assistance", "credit": "US Army Africa (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://www.flickr.com/photos/36281822@N08/15282849758", "__contentHash": "8c978344ba4d2dba8f570bed2dad0fd5c15027ad9c2e3bfe0db805fa92a85ed6", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07522866", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 20, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Thrive With Type 1 Diabetes 2026 — RECRUITING, NA. Interventions: TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm. Locations: Atlanta, Georgia, United States | Atlanta, Georgia, United States. This study aims to learn whether a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07522866" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 20, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-20:device-safety-watch", "slug": "2026-09-20-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-20T08:00:00.000Z", "updatedAt": "2026-09-20T10:17:01.251Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-20-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "1ae77ab447e4c0bed4b822af8225ee31d2d89ab0fc0642ac33703e016e209f47", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-20:how-type1cure-labels-evidence", "slug": "2026-09-20-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-20T08:00:00.000Z", "updatedAt": "2026-09-20T10:17:01.251Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-pmid-42789256.webp", "alt": "Refreshing breakfast arrangement with fruit, nuts, and tea for a healthy start.", "credit": "K. M. Sadik (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/healthy-breakfast-setup-with-fruit-and-tea-39865391/", "__contentHash": "ae464492c31b9c76fa43fc16e4588eecb9e7a4b2ecf9b7996c3b2c353ebf0528", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07522866", "openfda-device-recall:221103" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-20:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-20-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-20T08:00:00.000Z", "updatedAt": "2026-09-20T10:17:01.251Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-c53fe3a2e22bc559.webp", "alt": "Prism Clinical Research", "credit": "Gobonobo (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=166645633", "__contentHash": "59844a8e3b90390c88f4ee5fabc305f891d46510ae0a7287d352a2c319065906", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT07522866", "clinicaltrials:NCT05822609", "clinicaltrials:NCT07386340", "clinicaltrials:NCT06670625", "clinicaltrials:NCT07159282", "clinicaltrials:NCT06984133", "clinicaltrials:NCT06683391", "clinicaltrials:NCT05487534", "clinicaltrials:NCT03463564" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05822609", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-02" }, { "title": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature", "url": "https://clinicaltrials.gov/study/NCT07386340", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-21" }, { "title": "Intensive Dietary and Activity Counselling (IDAC)", "url": "https://clinicaltrials.gov/study/NCT06670625", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-13" }, { "title": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers", "url": "https://clinicaltrials.gov/study/NCT07159282", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-11" }, { "title": "Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06984133", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-22" }, { "title": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06683391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-02-25" }, { "title": "Do \"sugar Swings\" Impact the Brain Function and the Eating Behaviors of People with Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05487534", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-10-09" }, { "title": "Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type 1 Diabetic Patients", "url": "https://clinicaltrials.gov/study/NCT03463564", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2018-03-15" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "Thrive With Type 1 Diabetes 2026 — RECRUITING, NA. Interventions: TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm. Locations: Atlanta, Georgia, United States | Atlanta, Georgia, United States. This study aims to learn whether a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07522866" }, { "text": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Semaglutide, Placebo. Locations: Aurora, Colorado, United States | Seattle, Washington, United States | Spokane, Washington, United States. The primary objective of this study is to de...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05822609" }, { "text": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature — RECRUITING, NA. Interventions: Continuous Glucose Monitoring System. Locations: Escondido, California, United States. A prospective, multicenter evaluation of performance and safety of the Eversense Gemini System with f...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07386340" }, { "text": "Intensive Dietary and Activity Counselling (IDAC) — RECRUITING, NA. Interventions: IDAC+. Locations: Malmö, Sweden. The aim of this intervention study is to investigate if a intensive dietary and physical activity counselling during the first two years of life in childre...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06670625" }, { "text": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers — RECRUITING, PHASE4. Interventions: XWRAP. Locations: Hollywood, Florida, United States. A multicenter, prospective, controlled clinical trial evaluating the efficacy of a single layer placental-based allograft and stand...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07159282" }, { "text": "Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes — RECRUITING, NA. Interventions: Structured education program. Locations: Kuwait City, Sharq, Kuwait. Type 1 diabetes is becoming more common in Kuwaiti and Arab adolescents. Many young people with this condition struggle...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06984133" }, { "text": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes — RECRUITING, NA. Interventions: Oral Carbohydrate (CHO) Administration for Hypoglycemia Prevention and Treatment. Locations: Montreal, Quebec, Canada | Montreal, Quebec, Canada. The REMODAL trial is a randomized crossove...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06683391" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-20:research-watch", "slug": "2026-09-20-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-20T08:00:00.000Z", "updatedAt": "2026-09-20T10:17:01.251Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42457420.webp", "alt": "Barbara McClintock (1902-1992), Department of Genetics, Carnegie Institution at Cold Spring Harbor, New York, shown in her laboratory. This photograph was distr", "credit": "Smithsonian Institution /Science Service; Restored by Adam Cuerden (Wikimedia Commons)", "license": "Public domain", "sourceUrl": "https://commons.wikimedia.org/wiki/File:Barbara_McClintock_(1902-1992)_shown_in_her_laboratory_in_1947.jpg", "__contentHash": "7917092b2c3bbfa391d6f25dc112e5cf92543471dbb94559d4d283b76acd2b3d", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-20" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-19:daily-type-1-diabetes-briefing", "slug": "2026-09-19-daily-type-1-diabetes-briefing", "title": "September 19, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-19T08:00:00.000Z", "updatedAt": "2026-09-19T10:17:01.881Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-86657240ee74b599.webp", "alt": "A young female scientist with curly hair in a lab coat working in a laboratory setting.", "credit": "Mikhail Nilov (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/blurred-photo-of-a-woman-in-white-long-sleeves-8851610/", "__contentHash": "3804ec41a6435550381308f002990e1ac5792ce2316b2007373fb4e45f4ab39a", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07522866", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 19, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Thrive With Type 1 Diabetes 2026 — RECRUITING, NA. Interventions: TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm. Locations: Atlanta, Georgia, United States | Atlanta, Georgia, United States. This study aims to learn whether a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07522866" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 19, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-19:device-safety-watch", "slug": "2026-09-19-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-19T08:00:00.000Z", "updatedAt": "2026-09-19T10:17:01.881Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-19-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "e71bd9e7bd6d5fc365264fd737e899608e71b5018686392842480dda65a84e1c", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-19:how-type1cure-labels-evidence", "slug": "2026-09-19-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-19T08:00:00.000Z", "updatedAt": "2026-09-19T10:17:01.881Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-pmid-42807966.webp", "alt": "Black drongo (Dicrurus macrocercus) with it's healthy meal, Padma river, Rajshahi", "credit": "MHOvi07 (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=163377638", "__contentHash": "8e631bfe61bf391e4a7990ac03fa0f84c486e249700bc80749d1fd77fddf1549", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT07522866", "openfda-device-recall:221103" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-19:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-19-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-19T08:00:00.000Z", "updatedAt": "2026-09-19T10:17:01.881Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-efc1d0bf2a729c4c.webp", "alt": "Surrey Clinical Research Centre", "credit": "David Hawgood (Openverse / BY-SA 2.0)", "license": "Openverse BY-SA 2.0", "sourceUrl": "https://www.geograph.org.uk/photo/2585902", "__contentHash": "5ac8d44d9cf15f9f7d644419b61a1773724127dc4723fd3aee4e6a21287034f6", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT07522866", "clinicaltrials:NCT05822609", "clinicaltrials:NCT07386340", "clinicaltrials:NCT06670625", "clinicaltrials:NCT07159282", "clinicaltrials:NCT06984133", "clinicaltrials:NCT06683391", "clinicaltrials:NCT05487534", "clinicaltrials:NCT03463564" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "Thrive With Type 1 Diabetes 2026", "url": "https://clinicaltrials.gov/study/NCT07522866", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-06" }, { "title": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05822609", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-02" }, { "title": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature", "url": "https://clinicaltrials.gov/study/NCT07386340", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-21" }, { "title": "Intensive Dietary and Activity Counselling (IDAC)", "url": "https://clinicaltrials.gov/study/NCT06670625", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-13" }, { "title": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers", "url": "https://clinicaltrials.gov/study/NCT07159282", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-11" }, { "title": "Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06984133", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-22" }, { "title": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06683391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-02-25" }, { "title": "Do \"sugar Swings\" Impact the Brain Function and the Eating Behaviors of People with Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05487534", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-10-09" }, { "title": "Insulin Pump vs Multiple Daily Injections of Insulin and Glyco-metabolic Control in Type 1 Diabetic Patients", "url": "https://clinicaltrials.gov/study/NCT03463564", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2018-03-15" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "Thrive With Type 1 Diabetes 2026 — RECRUITING, NA. Interventions: TranS-C Intervention Arm, Attention Control Enhanced Usual Care (EUC) Arm. Locations: Atlanta, Georgia, United States | Atlanta, Georgia, United States. This study aims to learn whether a...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07522866" }, { "text": "Trial of Semaglutide for Diabetic Kidney Disease in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Semaglutide, Placebo. Locations: Aurora, Colorado, United States | Seattle, Washington, United States | Spokane, Washington, United States. The primary objective of this study is to de...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05822609" }, { "text": "Gemini Study: A Prospective, Multicenter Evaluation of Performance and Safety of the Eversense Gemini System With Flash Glucose Measurement Feature — RECRUITING, NA. Interventions: Continuous Glucose Monitoring System. Locations: Escondido, California, United States. A prospective, multicenter evaluation of performance and safety of the Eversense Gemini System with f...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07386340" }, { "text": "Intensive Dietary and Activity Counselling (IDAC) — RECRUITING, NA. Interventions: IDAC+. Locations: Malmö, Sweden. The aim of this intervention study is to investigate if a intensive dietary and physical activity counselling during the first two years of life in childre...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06670625" }, { "text": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers — RECRUITING, PHASE4. Interventions: XWRAP. Locations: Hollywood, Florida, United States. A multicenter, prospective, controlled clinical trial evaluating the efficacy of a single layer placental-based allograft and stand...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07159282" }, { "text": "Structured Education Program and Glycemic Control in Adolescents With Type 1 Diabetes — RECRUITING, NA. Interventions: Structured education program. Locations: Kuwait City, Sharq, Kuwait. Type 1 diabetes is becoming more common in Kuwaiti and Arab adolescents. Many young people with this condition struggle...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06984133" }, { "text": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes — RECRUITING, NA. Interventions: Oral Carbohydrate (CHO) Administration for Hypoglycemia Prevention and Treatment. Locations: Montreal, Quebec, Canada | Montreal, Quebec, Canada. The REMODAL trial is a randomized crossove...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06683391" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-19:research-watch", "slug": "2026-09-19-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-19T08:00:00.000Z", "updatedAt": "2026-09-19T10:17:01.881Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-4f6c8fa25c69af1b.webp", "alt": "A scientist works with a microscope in a bright, modern lab setting, wearing a lab coat.", "credit": "Zakir Rushanly (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/woman-in-white-robe-looking-through-microscope-11730899/", "__contentHash": "7dad3da187679e67f63417e61195ef6aacc2520a338b058657179949feacf494", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-19" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-18:daily-type-1-diabetes-briefing", "slug": "2026-09-18-daily-type-1-diabetes-briefing", "title": "September 18, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-18T08:00:00.000Z", "updatedAt": "2026-09-18T10:17:01.678Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-f837da806d80625a.webp", "alt": "Number of clinical research studies", "credit": "Neta Glebotzky (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=63623130", "__contentHash": "20ebbf5762d05018f0ee6b6f4a6533bb8abf16b29a035053fa21264adbd9432f", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT06411210", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment", "url": "https://clinicaltrials.gov/study/NCT06411210", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 18, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment — RECRUITING, PHASE2. Interventions: Semaglutide Pen Injector, Placebo. Locations: New Haven, Connecticut, United States. More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06411210" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 18, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-18:device-safety-watch", "slug": "2026-09-18-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-18T08:00:00.000Z", "updatedAt": "2026-09-18T10:17:01.678Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-18-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "8b5711148d10ced460a8ed2d4b229e31f2abe766ea24e51fd131fc33f9dd115a", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-18:how-type1cure-labels-evidence", "slug": "2026-09-18-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-18T08:00:00.000Z", "updatedAt": "2026-09-18T10:17:01.678Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-pmid-42528822.webp", "alt": "Bunches of healthy dill and fresh lettuce placed near heap of green onions on stall in grocery market during harvest season", "credit": "Atlantic Ambience (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/assorted-fresh-greens-in-market-5981707/", "__contentHash": "aecf5788dc5d216cce73207cfad59e6c7598a33636ab5737246a10ef1391d1b2", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT06411210", "openfda-device-recall:221103", "openfda-device-recall:221053" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment", "url": "https://clinicaltrials.gov/study/NCT06411210", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-18:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-18-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-18T08:00:00.000Z", "updatedAt": "2026-09-18T10:17:01.678Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-f59a0743df17b315.webp", "alt": "Variety of clinical research studies", "credit": "Neta Glebotzky (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=63623127", "__contentHash": "ca52b22915dce7ab05330acd9acddf22e29a36ad3a34ebffbf289d7927bb51b2", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT06411210", "clinicaltrials:NCT05505669", "clinicaltrials:NCT07634770", "clinicaltrials:NCT05498974", "clinicaltrials:NCT07159282", "clinicaltrials:NCT07059806", "clinicaltrials:NCT07317986", "clinicaltrials:NCT06803446", "clinicaltrials:NCT06683391", "clinicaltrials:NCT04449198" ], "sources": [ { "title": "Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment", "url": "https://clinicaltrials.gov/study/NCT06411210", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Circulating Biomarkers in the Development of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05505669", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-24" }, { "title": "Bioavailability, Biopotency and Food Effect Study of SCD0503 Compared to Subcutaneous Regular Human Insulin", "url": "https://clinicaltrials.gov/study/NCT07634770", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-09" }, { "title": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05498974", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers", "url": "https://clinicaltrials.gov/study/NCT07159282", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-11" }, { "title": "T1CARE: A Trial of a Novel Intervention to Address Social Determinants of Health in Young Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07059806", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-12" }, { "title": "CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada", "url": "https://clinicaltrials.gov/study/NCT07317986", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-05" }, { "title": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06803446", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-09-04" }, { "title": "Updating Preventive and Treatment Guidelines for Hypoglycemia in Individuals Living With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06683391", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-02-25" }, { "title": "Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1", "url": "https://clinicaltrials.gov/study/NCT04449198", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-01-28" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Obesity Complicating Type 1 Diabetes: GLP-1 Analogue Anti-obesity Treatment — RECRUITING, PHASE2. Interventions: Semaglutide Pen Injector, Placebo. Locations: New Haven, Connecticut, United States. More than 40% of young adults with type 1 diabetes (T1D) also have overweight or obesity. Each of t...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06411210" }, { "text": "Circulating Biomarkers in the Development of Type 1 Diabetes — RECRUITING. Interventions: One-time blood (up to 100 ml) will be drawn and the amount of blood drawn is based on weight. Saliva and urine will be collected during the blood draw visit.. Locations: Duarte, California, Un...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05505669" }, { "text": "Bioavailability, Biopotency and Food Effect Study of SCD0503 Compared to Subcutaneous Regular Human Insulin — RECRUITING, PHASE1. Interventions: oral insulin, Placebo A, subcutaneous insulin. Locations: Neuss, North Rhine-Westphalia, Germany. Reason for the study The participants have been diagnosed with type 1 diabetes and are...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07634770" }, { "text": "China Diabetes Type 1 Study (CD1S) by China Alliance for Type 1 Diabetes — RECRUITING. Interventions: Standard type 1 diabetes management model constructed by China Alliance for Type 1 Diabetes in each center. Locations: Lanzhou, Gansu, China | Shenzhen, Guangdong, China | Haikou, Hainan, Chin...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05498974" }, { "text": "A Multicenter, Prospective, Controlled Clinical Trial Evaluating the Efficacy of a Single Layer Placental-based Allograft and Standard of Care in the Management of Nonhealing Diabetic Foot Ulcers — RECRUITING, PHASE4. Interventions: XWRAP. Locations: Hollywood, Florida, United States. A multicenter, prospective, controlled clinical trial evaluating the efficacy of a single layer placental-based allograft and stand...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07159282" }, { "text": "T1CARE: A Trial of a Novel Intervention to Address Social Determinants of Health in Young Adults With Type 1 Diabetes — RECRUITING, NA. Interventions: T1CARE. Locations: New Haven, Connecticut, United States | New Haven, Connecticut, United States. Randomized controlled trial with a wait list control arm. Participants will be randomized...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07059806" }, { "text": "CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada — RECRUITING, NA. Interventions: Peer support meetings. Locations: Québec, Quebec, Canada. When you live with type 1 diabetes (T1D), it is easy to feel alone. Managing your own T1D or your child's T1D takes constant effor...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07317986" }, { "text": "Effects of Circadian Rhythm on Glycemic Regulation During Continuous Moderate Exercise and Intense Intermittent Disease in Adolescents Living With Type 1 Diabetes — RECRUITING, NA. Interventions: physical test. Locations: Loos, Nord, France. Interventional research with minimal risks and constraints on the effects of circadian rhythm on glycemic regulation during intense moderate,...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06803446" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-18:research-watch", "slug": "2026-09-18-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-18T08:00:00.000Z", "updatedAt": "2026-09-18T10:17:01.678Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-8a7aeb91eab09af0.webp", "alt": "a microscope with a microscope attached to it", "credit": "Indra Projects (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/a-microscope-with-a-microscope-attached-to-it-a_ldJ0EzbLI", "__contentHash": "c8327af07ff94d981ff0efb38f45c2db62a2696025ebe88b963a997057d89f70", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-18" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-17:daily-type-1-diabetes-briefing", "slug": "2026-09-17-daily-type-1-diabetes-briefing", "title": "September 17, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-17T08:00:00.000Z", "updatedAt": "2026-09-17T10:17:01.310Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-c9f7f1de3d395c16.webp", "alt": "Detailed view of laboratory glass vials held by a clamp with red handles, ideal for science stock images.", "credit": "Jess Loiterton (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/close-up-of-test-tubes-with-liquid-9259977/", "__contentHash": "9072538dd2711b3c73d80844dbe4fe44789df8d9fe66aaf3feec2cf578c29a62", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT07804849", "clinicaltrials:NCT07490964", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "clinicaltrials:NCT06144554", "openfda-device-recall:220614", "openfda-device-recall:220615" ], "sources": [ { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Polycystic Ovary Syndrome in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07490964", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-03" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06144554", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-01" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 17, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes — RECRUITING, PHASE2, PHASE3. Interventions: Verapamil oral, Placebo. Locations: Cairo, Egypt. Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verap...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07804849" }, { "text": "Polycystic Ovary Syndrome in Type 1 Diabetes — RECRUITING. Interventions: Type 1 diabetes mellitus, Elevated circulating androgen levels, Sex dimorphism. Locations: Madrid, Madrid, Spain. BACKGROUND Functional ovarian hyperandrogenism, including the polycystic ovary...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07490964" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 17, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-17:device-safety-watch", "slug": "2026-09-17-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-17T08:00:00.000Z", "updatedAt": "2026-09-17T10:17:01.310Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-17-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "641bbce1f973cddd63c492cf71a9b4b29fa7136b6fe8beb035560e4da9a6d82f", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-17:how-type1cure-labels-evidence", "slug": "2026-09-17-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-17T08:00:00.000Z", "updatedAt": "2026-09-17T10:17:01.310Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/lifestyle-pmid-42477667.webp", "alt": "Women exercising with resistance bands in a well-lit rustic studio, promoting fitness and health.", "credit": "Andrea Piacquadio (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/three-women-s-doing-exercises-863977/", "__contentHash": "5e04c5e657c2f43a0344704e1ed86fbbd32804160fb0d317f654da39f605a9d0", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT07804849", "clinicaltrials:NCT07490964", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103" ], "sources": [ { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Polycystic Ovary Syndrome in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07490964", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-03" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-17:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-17-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-17T08:00:00.000Z", "updatedAt": "2026-09-17T10:17:01.310Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-a60f43e70a1f094a.webp", "alt": "Feeding a laboratory rat", "credit": "Anna Marchenkova (Openverse / BY 4.0)", "license": "Openverse BY 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=64828896", "__contentHash": "7f506b54fb2f74a996f3a88444aff21a81c576f41f8ffccb7cfa328e0d0cb073", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07804849", "clinicaltrials:NCT07490964", "clinicaltrials:NCT06144554", "clinicaltrials:NCT07427134", "clinicaltrials:NCT07634770", "clinicaltrials:NCT03648918", "clinicaltrials:NCT06408207", "clinicaltrials:NCT06203106", "clinicaltrials:NCT06717893", "clinicaltrials:NCT05277532" ], "sources": [ { "title": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07804849", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-04" }, { "title": "Polycystic Ovary Syndrome in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07490964", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-03" }, { "title": "Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06144554", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-01" }, { "title": "Pediatric Insulin Plan Calculator for T1DM Management", "url": "https://clinicaltrials.gov/study/NCT07427134", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-09" }, { "title": "Bioavailability, Biopotency and Food Effect Study of SCD0503 Compared to Subcutaneous Regular Human Insulin", "url": "https://clinicaltrials.gov/study/NCT07634770", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-09" }, { "title": "Genetics Of Autoimmunity In Type I Diabetes", "url": "https://clinicaltrials.gov/study/NCT03648918", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-16" }, { "title": "CGM Academy for Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06408207", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-06" }, { "title": "NYSCF Scientific Discovery Biobank", "url": "https://clinicaltrials.gov/study/NCT06203106", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-03-03" }, { "title": "Clinical and Laboratory Characteristics of a Population of Children and Adolescents With Newly Diagnosed Type 1 Diabetes and Insulin Requirements at Onset", "url": "https://clinicaltrials.gov/study/NCT06717893", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-05" }, { "title": "Effect of Circadian Rhythm and Physical Exercise in Overweight Type 1 Diabetes Patients", "url": "https://clinicaltrials.gov/study/NCT05277532", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-10-15" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Oral Verapamil Among Newly Diagnosed Children and Adolescents With Type 1 Diabetes — RECRUITING, PHASE2, PHASE3. Interventions: Verapamil oral, Placebo. Locations: Cairo, Egypt. Type 1 diabetes (T1D) in children involves autoimmune destruction of pancreatic ß- cells, leading to insulin deficiency. Verap...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07804849" }, { "text": "Polycystic Ovary Syndrome in Type 1 Diabetes — RECRUITING. Interventions: Type 1 diabetes mellitus, Elevated circulating androgen levels, Sex dimorphism. Locations: Madrid, Madrid, Spain. BACKGROUND Functional ovarian hyperandrogenism, including the polycystic ovary...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07490964" }, { "text": "Post Market Registry for the Omnipod 5 System in Children and Adults With Type 1 Diabetes — RECRUITING. Interventions: Omnipod 5. Locations: Buffalo, New York, United States. This is a decentralized observational clinical registry to collect real-world evidence related to the safety and effectiveness of the Om...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06144554" }, { "text": "Pediatric Insulin Plan Calculator for T1DM Management — RECRUITING, NA. Interventions: Flexible Digital Insulin Dose Calculator. Locations: Mosul, Iraq | Lahore, Pakistan. This is a multi-centre, prospective, randomized, open-label controlled trial designed to evaluate the e...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07427134" }, { "text": "Bioavailability, Biopotency and Food Effect Study of SCD0503 Compared to Subcutaneous Regular Human Insulin — RECRUITING, PHASE1. Interventions: oral insulin, Placebo A, subcutaneous insulin. Locations: Neuss, North Rhine-Westphalia, Germany. Reason for the study The participants have been diagnosed with type 1 diabetes and are...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07634770" }, { "text": "Genetics Of Autoimmunity In Type I Diabetes — RECRUITING. Interventions: Blood Collection. Locations: Milwaukee, Wisconsin, United States. The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 dia...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03648918" }, { "text": "CGM Academy for Youth With Type 1 Diabetes — RECRUITING, NA. Interventions: CGM Academy. Locations: Los Angeles, California, United States. The goal of this randomized clinical trial is to compare the effects of a virtual education curriculum in blood glucose vari...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06408207" }, { "text": "NYSCF Scientific Discovery Biobank — RECRUITING. Interventions: Biological Sample Collection. Locations: New York, New York, United States. The New York Stem Cell Foundation (NYSCF) Research Institute is performing this research to accelerate diverse disea...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06203106" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-17:research-watch", "slug": "2026-09-17-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-17T08:00:00.000Z", "updatedAt": "2026-09-17T10:17:01.310Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-9f3a61a2db0d2c3e.webp", "alt": "A Meiji Techno microscope with multiple objective lenses above a black stage", "credit": "Logan Gutierrez (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/meiji-techno-microscope-with-objective-lenses-Rl9bIWKCVF0", "__contentHash": "a9a4473bb506db4ca61e9d2db2c7f5e21b5841a35e428b8d5f0ba5d882b67ada", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-17" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-16:daily-type-1-diabetes-briefing", "slug": "2026-09-16-daily-type-1-diabetes-briefing", "title": "September 16, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-16T08:00:00.000Z", "updatedAt": "2026-09-16T10:17:01.332Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-pmid-42523425.webp", "alt": "A scientist in a white lab coat using a laptop in a laboratory", "credit": "ThisisEngineering (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/scientist-using-laptop-in-laboratory-8yS04veb1TQ", "__contentHash": "2ebf7233b6ce3d4dc717b57568ca8a72a0a8888684a94f07a5e911171ad4ed0a", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT07061574", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT05478707", "openfda-device-recall:221103", "clinicaltrials:NCT06880835", "openfda-device-recall:221053", "openfda-device-recall:220614" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07061574", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-02" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05478707", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-12" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery", "url": "https://clinicaltrials.gov/study/NCT06880835", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-16" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 16, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes — RECRUITING, PHASE1, PHASE2. Interventions: Anti-thymocyte globulin (ATG), verapamil extended-release capsule, Adalimumab. Locations: San Francisco, California, United States | New Haven, Connecticut, United States | Gai...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07061574" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Dulaglutide, Placebo. Locations: Orlando, Florida, United States. The investigators will test the hypothesis that, in adults with type 1 diabetes (T1D), glucagon-like peptide-1 recepto...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05478707" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 16, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-16:device-safety-watch", "slug": "2026-09-16-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-16T08:00:00.000Z", "updatedAt": "2026-09-16T10:17:01.332Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-16-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "5c7a8a920cc12db3144fe84f6e37dd13de73e54e00477f0d4d392537a8c01897", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-16:how-type1cure-labels-evidence", "slug": "2026-09-16-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-16T08:00:00.000Z", "updatedAt": "2026-09-16T10:17:01.332Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42398515.webp", "alt": "Health, Doctor and Legal Issues", "credit": "weiss_paarz_photos (Openverse / BY-SA 2.0)", "license": "Openverse BY-SA 2.0", "sourceUrl": "https://www.flickr.com/photos/141290938@N03/27256428336", "__contentHash": "e7c2bbe5e5a62901756f0802644a4faf72e7a9eef8c3640a5b572ab70c38ff9b", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT07061574", "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT05478707" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07061574", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-02" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05478707", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-12" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-16:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-16-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-16T08:00:00.000Z", "updatedAt": "2026-09-16T10:17:01.332Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-647705c20f3da22e.webp", "alt": "Doctor examining patient's eyes with equipment", "credit": "Navy Medicine (Unsplash)", "license": "Unsplash License", "sourceUrl": "https://unsplash.com/photos/doctor-examining-patients-eyes-with-equipment-Dpjx9BiTftQ", "__contentHash": "341904ebd1dde56df6259a7a37063bffc6dae0e45a21ec6a855e92ee842b3402", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05540704", "clinicaltrials:NCT07061574", "clinicaltrials:NCT05478707", "clinicaltrials:NCT06880835", "clinicaltrials:NCT05594706", "clinicaltrials:NCT06748963", "clinicaltrials:NCT07186660", "clinicaltrials:NCT06630585", "clinicaltrials:NCT06981234", "clinicaltrials:NCT06513247" ], "sources": [ { "title": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05540704", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-08" }, { "title": "A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07061574", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-09-02" }, { "title": "Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05478707", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-12" }, { "title": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery", "url": "https://clinicaltrials.gov/study/NCT06880835", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-07-16" }, { "title": "Anhydroglucitol in Children With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05594706", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-18" }, { "title": "Fasted Exercise Training in Type 1 Diabetes (FED-T1D)", "url": "https://clinicaltrials.gov/study/NCT06748963", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-05-08" }, { "title": "Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07186660", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-25" }, { "title": "GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06630585", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-26" }, { "title": "Acetazolamide in Persons With Type 1 Diabetes - Crossover Trial", "url": "https://clinicaltrials.gov/study/NCT06981234", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-06-17" }, { "title": "Screening Program for Type 1 Diabetes in a High-Risk Population", "url": "https://clinicaltrials.gov/study/NCT06513247", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-07-22" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Study Comparing Acceptance and Commitment Therapy to Supportive Diabetes Counseling and a Waitlist Control for Eating Disorders in Type 1 Diabetes — RECRUITING, NA. Interventions: ACT, Supportive Diabetes Counseling. Locations: Durham, North Carolina, United States | Providence, Rhode Island, United States. The goal of this clinical trial is to test whether a new in...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05540704" }, { "text": "A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes — RECRUITING, PHASE1, PHASE2. Interventions: Anti-thymocyte globulin (ATG), verapamil extended-release capsule, Adalimumab. Locations: San Francisco, California, United States | New Haven, Connecticut, United States | Gai...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07061574" }, { "text": "Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Dulaglutide, Placebo. Locations: Orlando, Florida, United States. The investigators will test the hypothesis that, in adults with type 1 diabetes (T1D), glucagon-like peptide-1 recepto...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05478707" }, { "text": "Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery — RECRUITING, NA. Interventions: Control IQ + sleep or exercise activity with TI. Locations: Louisville, Kentucky, United States | Philadelphia, Pennsylvania, United States | Seattle, Washington, United States. This inves...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06880835" }, { "text": "Anhydroglucitol in Children With Type 1 Diabetes — RECRUITING. Interventions: Measurement of blood levels of 1,5-anhydroglucitol. Locations: Geneva, Canton of Geneva, Switzerland. The investigators will measure blood levels of 1,5-anhydroglucitol in children with type 1...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05594706" }, { "text": "Fasted Exercise Training in Type 1 Diabetes (FED-T1D) — RECRUITING, NA. Interventions: Fasted Exercise, Postprandial Exercise. Locations: Edmonton, Alberta, Canada. This study compares aerobic exercise training performed before breakfast (i.e., in the fasted state) to simila...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06748963" }, { "text": "Evaluation of a Novel Insulin Sensitizer in People With Type 1 Diabetes — RECRUITING, PHASE2. Interventions: CIR-0602K, Placebo. Locations: Charlottesville, Virginia, United States. The purpose of this study is to see if the study drug CIR-0602K will improve glucose time-in-range and/or lower...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07186660" }, { "text": "GIP/GLP-1RA as Adjunctive to Automated Insulin Delivery in Adults With Type 1 Diabetes — RECRUITING, PHASE3. Interventions: Tirzepatide. Locations: Chêne-Bougeries, Canton of Geneva, Switzerland | Olten, Canton of Solothurn, Switzerland | Lucerne, Switzerland. Blood glucose management in type 1 diabetes (T1...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06630585" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-16:research-watch", "slug": "2026-09-16-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-16T08:00:00.000Z", "updatedAt": "2026-09-16T10:17:01.332Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-yt-7gv298nsgl0.webp", "alt": "20160926 Clinical Research Centre Malmo 0058 (29343224923)", "credit": "News Oresund (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=101350159", "__contentHash": "4a3991910603bd38f54e609e8c319bc74f3b17c5b7ecf18b80aaff65a361196b", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-16" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-15:daily-type-1-diabetes-briefing", "slug": "2026-09-15-daily-type-1-diabetes-briefing", "title": "September 15, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-15T08:00:00.000Z", "updatedAt": "2026-09-15T10:17:01.527Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-yt-qu-etdym6-8.webp", "alt": "CHA Vaccine Research Institute pipline", "credit": "CHA Vaccine Institute (Openverse / CC0 1.0)", "license": "Openverse CC0 1.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=158082291", "__contentHash": "124a46b0f1416c255c78718d38ceabbb2535d556809a54ecf8f716ae961cdb3c", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT05777330", "clinicaltrials:NCT07745244", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05777330", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-17" }, { "title": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System", "url": "https://clinicaltrials.gov/study/NCT07745244", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 15, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes — RECRUITING, NA. Interventions: Oral glucose tolerance test (OGTT), Hyperglycemic clamp test, Continuous glucose monitoring. Locations: Liège, Liège, Belgium | Bruges, West-Vlaanderen, Belgium | Antwerp, Belgium. The goa...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05777330" }, { "text": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System — RECRUITING, NA. Interventions: GS3 CGM. Locations: Zibo, Shandong, China. The study is to evaluate the accuracy and safety of a real-time CGM system among adult patients with type 1 diabetes with respect to reference ve...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07745244" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 15, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-15:device-safety-watch", "slug": "2026-09-15-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-15T08:00:00.000Z", "updatedAt": "2026-09-15T10:17:01.527Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-15-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "6ed3f7e39fee2831c2063b5942da81fe7c00620f507ae4c8ed1914a7f03339f0", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-15:how-type1cure-labels-evidence", "slug": "2026-09-15-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-15T08:00:00.000Z", "updatedAt": "2026-09-15T10:17:01.527Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42411376.webp", "alt": "Close-up of a healthcare professional measuring an infant using a medical ruler.", "credit": "Wellington Tavares (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/measuring-infant-with-medical-ruler-tool-33919288/", "__contentHash": "83bbf1865e9a8b7d67175c92e62bb73d56c76d85a4742a63352ea6e665426af9", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT05777330", "clinicaltrials:NCT07745244", "openfda-device-recall:221103" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05777330", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-17" }, { "title": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System", "url": "https://clinicaltrials.gov/study/NCT07745244", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-15:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-15-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-15T08:00:00.000Z", "updatedAt": "2026-09-15T10:17:01.527Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-signal-f43682760fbf2366.webp", "alt": "A medical professional checking patient reports with a clipboard in an office setting.", "credit": "cottonbro studio (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/hands-of-doctor-holding-notepad-and-pen-7578802/", "__contentHash": "9baaa9550e7e5875329890c9602a3271bad5558b646be7410e0cf68baf2eee08", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05777330", "clinicaltrials:NCT07745244", "clinicaltrials:NCT03648918", "clinicaltrials:NCT05188027", "clinicaltrials:NCT07317986", "clinicaltrials:NCT07125365", "clinicaltrials:NCT05585983", "clinicaltrials:NCT04428658", "clinicaltrials:NCT04039945", "clinicaltrials:NCT06287840" ], "sources": [ { "title": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05777330", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-17" }, { "title": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System", "url": "https://clinicaltrials.gov/study/NCT07745244", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Genetics Of Autoimmunity In Type I Diabetes", "url": "https://clinicaltrials.gov/study/NCT03648918", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-16" }, { "title": "Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05188027", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-16" }, { "title": "CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada", "url": "https://clinicaltrials.gov/study/NCT07317986", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-05" }, { "title": "UK Islet Autoantibody Registry", "url": "https://clinicaltrials.gov/study/NCT07125365", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-08-15" }, { "title": "INfluenza VaccInation To Mitigate typE 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05585983", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-22" }, { "title": "Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04428658", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-03-27" }, { "title": "Fr1da Early Diagnosis and Care of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04039945", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-17" }, { "title": "Canadian Bone Strength Development Study", "url": "https://clinicaltrials.gov/study/NCT06287840", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-03-06" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes — RECRUITING, NA. Interventions: Oral glucose tolerance test (OGTT), Hyperglycemic clamp test, Continuous glucose monitoring. Locations: Liège, Liège, Belgium | Bruges, West-Vlaanderen, Belgium | Antwerp, Belgium. The goa...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05777330" }, { "text": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System — RECRUITING, NA. Interventions: GS3 CGM. Locations: Zibo, Shandong, China. The study is to evaluate the accuracy and safety of a real-time CGM system among adult patients with type 1 diabetes with respect to reference ve...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07745244" }, { "text": "Genetics Of Autoimmunity In Type I Diabetes — RECRUITING. Interventions: Blood Collection. Locations: Milwaukee, Wisconsin, United States. The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 dia...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03648918" }, { "text": "Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes — RECRUITING, NA. Interventions: Aerobic Exercise, Resistance Exercise, No exercise. Locations: Edmonton, Alberta, Canada | Montreal, Quebec, Canada. Participants will be asked to wear a continuous glucose monitor for at...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05188027" }, { "text": "CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada — RECRUITING, NA. Interventions: Peer support meetings. Locations: Québec, Quebec, Canada. When you live with type 1 diabetes (T1D), it is easy to feel alone. Managing your own T1D or your child's T1D takes constant effor...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07317986" }, { "text": "UK Islet Autoantibody Registry — RECRUITING. Locations: Oxford, Oxfordshire, United Kingdom. Type 1 diabetes (T1D) is a life-long condition where the immune system destroys part of the body (the pancreas) which makes the chemical, insulin. Insulin is n...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07125365" }, { "text": "INfluenza VaccInation To Mitigate typE 1 Diabetes — RECRUITING, PHASE4. Interventions: Vaxigrip Tetra Sanofi Pasteur Europe. Locations: Aalborg, Denmark | Aarhus, Denmark | Copenhagen, Denmark. In a multicenter, prospective, randomized, controlled clinical trial to compa...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05585983" }, { "text": "Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: Supplemental video visits, Standard of Care, Supplemental remote monitoring. Locations: Sacramento, California, United States. This study will test the hypothesis that supplemental synchro...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04428658" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-15:research-watch", "slug": "2026-09-15-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-15T08:00:00.000Z", "updatedAt": "2026-09-15T10:17:01.527Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42348779.webp", "alt": "Medical Laboratory", "credit": "ben.dracup (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://www.flickr.com/photos/186856158@N06/49501365313", "__contentHash": "211d812ee9213cc3b7efe5997bf42f6b14b2867a2bedd16150633b158afa4560", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-15" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-09-14:daily-type-1-diabetes-briefing", "slug": "2026-09-14-daily-type-1-diabetes-briefing", "title": "September 14, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-14T08:00:00.000Z", "updatedAt": "2026-09-14T20:17:01.218Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/living-pmid-42786561.webp", "alt": "File:Dominique Wilkins speaks to an attentive group at the Diabetes Living Room in Philadelphia.jpg", "credit": "Kpat827 (Openverse / BY-SA 3.0)", "license": "Openverse BY-SA 3.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=36969216", "__contentHash": "4e52b11bc382addaca9d83be4031586eebeeea7649f86864dad090c556831e36", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT05777330", "clinicaltrials:NCT07745244", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05777330", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-17" }, { "title": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System", "url": "https://clinicaltrials.gov/study/NCT07745244", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The September 14, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes — RECRUITING, NA. Interventions: Oral glucose tolerance test (OGTT), Hyperglycemic clamp test, Continuous glucose monitoring. Locations: Liège, Liège, Belgium | Bruges, West-Vlaanderen, Belgium | Antwerp, Belgium. The goa...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05777330" }, { "text": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System — RECRUITING, NA. Interventions: GS3 CGM. Locations: Zibo, Shandong, China. The study is to evaluate the accuracy and safety of a real-time CGM system among adult patients with type 1 diabetes with respect to reference ve...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07745244" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "September 14, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-09-14:device-safety-watch", "slug": "2026-09-14-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-14T08:00:00.000Z", "updatedAt": "2026-09-14T20:17:01.218Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-09-14-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "b034596ede4068d6f8b66228907d31590a3677fea114f60cd7672d58e8ada5f7", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "openfda-device-recall:221103", "openfda-device-recall:221053", "openfda-device-recall:220614", "openfda-device-recall:220615", "openfda-device-recall:220616", "openfda-device-recall:220303", "openfda-device-recall:219288" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-08" }, { "title": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-30" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782; — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW — Loaner insulin pumps may have been cleaned with chemically incompatible products that could damage the pump case or keypad, allow moisture ingress, and result in insulin over- or under-delivery, potentially causing hypo...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570" }, { "text": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android) — For MiniMed Go app version 1.0.0 and 1.1.0, when the Set day and night is turned OFF and missed dose or Correct high glucose alerts are enabled, the associated alerts will not be triggered during the nighttime. This cou...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, REF: MMT-1885, MMT-1886, MMT-1895, MMT-1896 — A software anomaly can occur when the pump is paired with the Instinct sensor. Under certain circumstances, the pump unexpectedly stops delivering insulin and displays two error messages back-to-back: Pump Error 53 foll...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221053" }, { "text": "Insulet Corporation: Omnipod 5 Pods. Includes the below Model/REF Numbers: 1. POD-OMNI-I1-6720. 2. POD-OMNI-I1-6220. 3. OMNI-I1-6729 (10-Pack), OMNI-I1-6720 (Single Pod). 4. OMNI-I1-6220. 5. OMNI-I1-6... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220614" }, { "text": "Insulet Corporation: Omnipod DASH Pod. Includes the below Model/REF Numbers: 1. POD-BLE-I1-525 (5-Pack), POD-BLE-I1-520 (Single Pod). 2. POD-BLE-I1-529 (10-Pack), POD-BLE-I1-520 (Single Pod). 3. BLE-I... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220615" }, { "text": "Insulet Corporation: Omnipod (Eros) Pod. Includes the below Model/REF Numbers: 1. POD-ZXP425 (10 Pack), POD- ZXP420 (Single Pod). 2. ZXR425 (10-Pack), ZXR420 (Single Pod). 3. ZXP425 (10 Pack), ZXP420... — External soft cannula damage during manufacturing that results in insulin leaking around the Pod instead of being delivered to the user regardless of basal or bolus delivery. The primary failure mode is pump under-deliv...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220616" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-09-14:how-type1cure-labels-evidence", "slug": "2026-09-14-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-14T08:00:00.000Z", "updatedAt": "2026-09-14T20:17:01.218Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42616125.webp", "alt": "A female doctor uses a stethoscope to listen to a young boy's heartbeat, conducting a health check outdoors.", "credit": "Tahir Xəlfəquliyev (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/female-doctor-examining-boy-s-heartbeat-outdoors-39296745/", "__contentHash": "aed59ac62bd73cf4b7f7ec2e71b2d59f3f13bf7be4838f40a3f5decec988902c", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "openfda-device-recall:221440", "openfda-device-recall:221569", "openfda-device-recall:221570", "clinicaltrials:NCT05777330", "clinicaltrials:NCT07745244", "openfda-device-recall:221103" ], "sources": [ { "title": "Medtronic MiniMed, Inc.: MiniMed 640G Insulin Pump, Model: MMT-1711, MMT-1712;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221440", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump, Model: MMT-1781, MMT-1782;", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221569", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump, Model: MMT-1885CLW, MMT-1886CLW", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221570", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-08-18" }, { "title": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05777330", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-17" }, { "title": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System", "url": "https://clinicaltrials.gov/study/NCT07745244", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Medtronic MiniMed, Inc.: MiniMed Go App, Model: MMT-8600 (iOS), MMT-8601 (Android)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=221103", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-07-23" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-09-14:recruiting-type-1-diabetes-trials-watch", "slug": "2026-09-14-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-14T08:00:00.000Z", "updatedAt": "2026-09-14T20:17:01.218Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/diagnosis-pmid-42375207.webp", "alt": "A doctor holds a pill bottle while consulting with an elderly patient. A stethoscope and prescriptions are visible.", "credit": "Towfiqu barbhuiya (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/hand-holding-medicine-over-paper-on-desk-11370618/", "__contentHash": "8d9da5baa1a07d7ab6c26dafcb32be3ca7da069978d6993f5a589f9469ba395f", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT05777330", "clinicaltrials:NCT07745244", "clinicaltrials:NCT03648918", "clinicaltrials:NCT05188027", "clinicaltrials:NCT07317986", "clinicaltrials:NCT07125365", "clinicaltrials:NCT05585983", "clinicaltrials:NCT04428658", "clinicaltrials:NCT04039945", "clinicaltrials:NCT06287840" ], "sources": [ { "title": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05777330", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-17" }, { "title": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System", "url": "https://clinicaltrials.gov/study/NCT07745244", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-08-04" }, { "title": "Genetics Of Autoimmunity In Type I Diabetes", "url": "https://clinicaltrials.gov/study/NCT03648918", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-16" }, { "title": "Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05188027", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-03-16" }, { "title": "CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada", "url": "https://clinicaltrials.gov/study/NCT07317986", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-01-05" }, { "title": "UK Islet Autoantibody Registry", "url": "https://clinicaltrials.gov/study/NCT07125365", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-08-15" }, { "title": "INfluenza VaccInation To Mitigate typE 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05585983", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-05-22" }, { "title": "Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04428658", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-03-27" }, { "title": "Fr1da Early Diagnosis and Care of Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT04039945", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-12-17" }, { "title": "Canadian Bone Strength Development Study", "url": "https://clinicaltrials.gov/study/NCT06287840", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2024-03-06" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "Continuous Monitoring of Glycemic Variability to Predict Dys- and Hyperglycemia in Asymptomatic Type 1 Diabetes — RECRUITING, NA. Interventions: Oral glucose tolerance test (OGTT), Hyperglycemic clamp test, Continuous glucose monitoring. Locations: Liège, Liège, Belgium | Bruges, West-Vlaanderen, Belgium | Antwerp, Belgium. The goa...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05777330" }, { "text": "Evaluation of the Accuracy and Safety of a Continuous Glucose Monitoring System — RECRUITING, NA. Interventions: GS3 CGM. Locations: Zibo, Shandong, China. The study is to evaluate the accuracy and safety of a real-time CGM system among adult patients with type 1 diabetes with respect to reference ve...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07745244" }, { "text": "Genetics Of Autoimmunity In Type I Diabetes — RECRUITING. Interventions: Blood Collection. Locations: Milwaukee, Wisconsin, United States. The purpose of this study is to gain more information about the step-by-step process that causes someone to develop type 1 dia...", "sourceUrl": "https://clinicaltrials.gov/study/NCT03648918" }, { "text": "Aerobic vs Resistance Exercise in Post-menopausal Women With Type 1 Diabetes — RECRUITING, NA. Interventions: Aerobic Exercise, Resistance Exercise, No exercise. Locations: Edmonton, Alberta, Canada | Montreal, Quebec, Canada. Participants will be asked to wear a continuous glucose monitor for at...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05188027" }, { "text": "CommuniT1D: A Customized Virtual Peer Support Program For People Living With Type 1 Diabetes In Canada — RECRUITING, NA. Interventions: Peer support meetings. Locations: Québec, Quebec, Canada. When you live with type 1 diabetes (T1D), it is easy to feel alone. Managing your own T1D or your child's T1D takes constant effor...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07317986" }, { "text": "UK Islet Autoantibody Registry — RECRUITING. Locations: Oxford, Oxfordshire, United Kingdom. Type 1 diabetes (T1D) is a life-long condition where the immune system destroys part of the body (the pancreas) which makes the chemical, insulin. Insulin is n...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07125365" }, { "text": "INfluenza VaccInation To Mitigate typE 1 Diabetes — RECRUITING, PHASE4. Interventions: Vaxigrip Tetra Sanofi Pasteur Europe. Locations: Aalborg, Denmark | Aarhus, Denmark | Copenhagen, Denmark. In a multicenter, prospective, randomized, controlled clinical trial to compa...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05585983" }, { "text": "Randomized Trial of Supplemental Synchronous and Asynchronous Telehealth to Improve Glycemic Control for Pediatric Patients With Type 1 Diabetes — RECRUITING, NA. Interventions: Supplemental video visits, Standard of Care, Supplemental remote monitoring. Locations: Sacramento, California, United States. This study will test the hypothesis that supplemental synchro...", "sourceUrl": "https://clinicaltrials.gov/study/NCT04428658" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-09-14:research-watch", "slug": "2026-09-14-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-09-14T08:00:00.000Z", "updatedAt": "2026-09-14T20:17:01.218Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42501805.webp", "alt": "Prorew medical laboratory and Diagnostics", "credit": "ChinecheremN (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=194669721", "__contentHash": "e70d769f9a2296d3884bb17813e4d82f1c4ae40450d74886e1ebd4ede26fa88a", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42598441", "pubmed:42430551", "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:42733922", "pubmed:42539632", "pubmed:42524453", "pubmed:42395262", "pubmed:41823267", "pubmed:42699725", "pubmed:42642325" ], "sources": [ { "title": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival.", "url": "https://pubmed.ncbi.nlm.nih.gov/42598441/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells.", "url": "https://pubmed.ncbi.nlm.nih.gov/42430551/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression.", "url": "https://pubmed.ncbi.nlm.nih.gov/42733922/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications.", "url": "https://pubmed.ncbi.nlm.nih.gov/42539632/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise.", "url": "https://pubmed.ncbi.nlm.nih.gov/42524453/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients.", "url": "https://pubmed.ncbi.nlm.nih.gov/42395262/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Determinants, implementation strategies, and mechanisms of the 4T Program.", "url": "https://pubmed.ncbi.nlm.nih.gov/42699725/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" }, { "title": "Interleukin-1 mediates innate immune signaling and antiviral defense in islets.", "url": "https://pubmed.ncbi.nlm.nih.gov/42642325/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-09-14" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Retrievable \"sea-island\" microstructured zwitterionic-silicone hydrogel devices: augmented oxygen transport and anti-fibrosis for sustaining islet survival. — Bioactive materials. Authors: Chen D, Wang H, Tang Y. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42598441/" }, { "text": "IFNα and bleomycin-induced DNA damage activate distinct stress responses in human islets and induced pluripotent stem cell-derived islet cells. — Islets. Authors: Akbari Motlagh R, Rampazzo Morelli N, Alcasid N. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42430551/" }, { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Deletion of the T1D risk gene Ormdl3 in β-cells does not impact disease progression. — Biochemistry and biophysics reports. Authors: Ou Q, Jones EF, Currey K. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42733922/" }, { "text": "Glutamate-glutamine axis in pancreatic β-cells: mechanistic insights and therapeutic prospects in diabetes and its complications. — Journal of diabetes and metabolic disorders. Authors: Olatunde A, Disina HB, Eyitayo AR. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42539632/" }, { "text": "Perceptions of adults with type 1 diabetes mellitus about diabetes management and exercise. — Human factors in healthcare. Authors: Swaminath M, Griggs SA, Lukasik J. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42524453/" }, { "text": "AutoBiGluNet: transformer-based time series modeling for blood glucose prediction in Type 1 diabetes patients. — Health information science and systems. Authors: Sarwar MA, Maqsood S, Belousoviene E. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42395262/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } }, { "id": "blog:2026-07-01:daily-type-1-diabetes-briefing", "slug": "2026-07-01-daily-type-1-diabetes-briefing", "title": "July 1, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "dek": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance.", "category": "Daily Briefing", "topic": "daily-brief", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-07-01T08:00:00.000Z", "updatedAt": "2026-07-01T20:45:40.320Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42440197.webp", "alt": "European Molecular Biology Laboratory (EMBL) - July 2022 10", "credit": "Luis Fernando Flores LAB (Openverse / BY-SA 4.0)", "license": "Openverse BY-SA 4.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=164359694", "__contentHash": "ae74a1d0b598ac379ebd1c029af6be27c9eacd40493641caff366857ab012e90", "blogCoverVersion": 1 }, "tags": [ "daily briefing", "type 1 diabetes", "trials", "device safety", "research" ], "sourceItemIds": [ "openfda-device-recall:220303", "clinicaltrials:NCT07224321", "openfda-device-recall:219288", "openfda-device-recall:219289", "openfda-device-recall:219290", "openfda-device-recall:219498", "clinicaltrials:NCT07341373", "openfda-device-recall:219130", "clinicaltrials:NCT05899439", "openfda-device-recall:217834" ], "sources": [ { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07224321", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-16" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM watchOS App Model/Catalog Number: SW13355 Software Version: Versions 2.9.0 through 2.11.2 Pr...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219289", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom ONE+ Continuous Glucose Monitoring System Product Name: Dexcom ONE+ iOS CGM App Model/Catalog Number: SW14244 Software Version: versions 1.5.0 and 1.6.0 Product...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219290", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "North American Rescue LLC.: AIDBAGs are first aid kits of convenience composed of individually labeled devices designed as specialty first aid kits designed for the appropriate level provider to evaluate and...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219498", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-29" }, { "title": "A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500", "url": "https://clinicaltrials.gov/study/NCT07341373", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "FDA device recall: Omnipod 5 Pods. Model/Catalog number: PT-001662 ASM 5PK Pod STRL OPS G6G7", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219130", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-10" }, { "title": "Immune Function and the Progression to T1D", "url": "https://clinicaltrials.gov/study/NCT05899439", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-09" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump (MMT-1760, MMT-1761, MMT-1762, MMT-1780, MMT-1781, MMT-1782)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=217834", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-02" } ], "sections": [ { "heading": "The short version", "paragraphs": [ "The July 1, 2026 feed is strongest in three lanes: device safety, recruiting studies, and recent research records. Type1Cure treats safety and trial records as higher-priority signals because they can affect what a family may need to check, ask, or watch next.", "This is not a medical recommendation. It is a source map and plain-English triage layer designed to help families decide what deserves a closer look with their care team." ] }, { "heading": "Signals in the feed", "bullets": [ { "text": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ... — Certain lots of Dexcom G7 sensors originally designated as scrap and intended for destruction were stolen during the destruction process. The sensors were later sold to pharmacies and distributors by Pharmsource, LLC. L...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303" }, { "text": "INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Technosphere Insulin, Technosphere Insulin, Basal insulin. Locations: Los Angeles, California, United States | San Francisco, California, United States | Aurora, Colorado, United State...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07224321" }, { "text": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc... — A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV noti...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288" }, { "text": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM watchOS App Model/Catalog Number: SW13355 Software Version: Versions 2.9.0 through 2.11.2 Pr... — A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV noti...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219289" }, { "text": "Dexcom, Inc.: Brand Name: Dexcom ONE+ Continuous Glucose Monitoring System Product Name: Dexcom ONE+ iOS CGM App Model/Catalog Number: SW14244 Software Version: versions 1.5.0 and 1.6.0 Product... — A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV noti...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219290" }, { "text": "North American Rescue LLC.: AIDBAGs are first aid kits of convenience composed of individually labeled devices designed as specialty first aid kits designed for the appropriate level provider to evaluate and... — Kits contain the McKesson TRUE Metrix PRO Professional Monitoring Blood Glucose System that has been recalled for an issue with the software design of the E-5 Error Code where the meter displays an E-5 error code for a...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219498" }, { "text": "A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500 — RECRUITING, PHASE1. Interventions: Portal Insulin U-500, Portal Insulin U-500, Portal Insulin U-500. Locations: Chula Vista, California, United States. The goal of this clinical trial is to assess the safety of a new U5...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07341373" } ] }, { "heading": "How to use this briefing", "paragraphs": [ "Start with the evidence label. Official registry and regulator records are not the same thing as advice, but they are stronger source material than a repost, rumor, or promotional headline.", "For trials, check eligibility, location, burden, intervention, and contact details at the original registry. For device safety, check exact product names, models, lot numbers, software versions, and manufacturer instructions." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "July 1, 2026 Type 1 diabetes briefing: trials, device safety, and research signals", "description": "A daily Type1Cure briefing built from current official and public source pulls, with each item labeled by source, evidence class, and family relevance." } }, { "id": "blog:2026-07-01:device-safety-watch", "slug": "2026-07-01-device-safety-watch", "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "dek": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records.", "category": "Device Safety", "topic": "device-safety", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-07-01T08:00:00.000Z", "updatedAt": "2026-07-01T20:45:40.320Z", "readingTimeMinutes": 3, "image": { "src": "/images/blog/2026-07-01-device-safety-watch.webp", "alt": "Editorial illustration for Type 1 diabetes device safety watch: latest FDA recall signals families should review", "credit": "Type1Cure editorial illustration", "license": "Project-owned generated artwork", "__contentHash": "4fba40c2ac1e7801e0431166e8608e9bfd313b99ad4e459935ebdaf81b0f4cf2", "blogCoverVersion": 1 }, "tags": [ "device safety", "FDA recalls", "CGM", "insulin pump", "Type 1 diabetes" ], "sourceItemIds": [ "openfda-device-recall:220303", "openfda-device-recall:219288", "openfda-device-recall:219289", "openfda-device-recall:219290", "openfda-device-recall:219498", "openfda-device-recall:219130", "openfda-device-recall:217834", "openfda-device-recall:218909", "openfda-device-recall:218910", "openfda-device-recall:219223" ], "sources": [ { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM watchOS App Model/Catalog Number: SW13355 Software Version: Versions 2.9.0 through 2.11.2 Pr...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219289", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom ONE+ Continuous Glucose Monitoring System Product Name: Dexcom ONE+ iOS CGM App Model/Catalog Number: SW14244 Software Version: versions 1.5.0 and 1.6.0 Product...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219290", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "North American Rescue LLC.: AIDBAGs are first aid kits of convenience composed of individually labeled devices designed as specialty first aid kits designed for the appropriate level provider to evaluate and...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219498", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-29" }, { "title": "FDA device recall: Omnipod 5 Pods. Model/Catalog number: PT-001662 ASM 5PK Pod STRL OPS G6G7", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219130", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-10" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump (MMT-1760, MMT-1761, MMT-1762, MMT-1780, MMT-1781, MMT-1782)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=217834", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-02" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 630G Insulin Pump (MMT-1714, MMT-1715, MMT-1754, MMT-1755)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=218909", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-02" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 780G Insulin Pump (MMT-1884, MMT-1885, MMT-1886, MMT-1894, MMT-1895, MMT-1896)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=218910", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-02" }, { "title": "Medtronic MiniMed, Inc.: MiniMed 770G Insulin Pump (MMT-1880, MMT-1881, MMT-1882, MMT-1890, MMT-1891, MMT-1892)", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219223", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-02" } ], "sections": [ { "heading": "Why this lane comes first", "paragraphs": [ "For a Type 1 diabetes family, device and supply failures can become urgent faster than ordinary research news. A recall record may point to a software issue, model-specific device problem, replacement path, or safety instruction that deserves immediate review.", "The right workflow is product-specific: compare the exact device, app, model, lot, and instructions in the official source before assuming a recall applies." ] }, { "heading": "Current safety records in the feed", "bullets": [ { "text": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ... — Certain lots of Dexcom G7 sensors originally designated as scrap and intended for destruction were stolen during the destruction process. The sensors were later sold to pharmacies and distributors by Pharmsource, LLC. L...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303" }, { "text": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc... — A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV noti...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288" }, { "text": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM watchOS App Model/Catalog Number: SW13355 Software Version: Versions 2.9.0 through 2.11.2 Pr... — A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV noti...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219289" }, { "text": "Dexcom, Inc.: Brand Name: Dexcom ONE+ Continuous Glucose Monitoring System Product Name: Dexcom ONE+ iOS CGM App Model/Catalog Number: SW14244 Software Version: versions 1.5.0 and 1.6.0 Product... — A software defect in which a low-priority file I/O check blocks the higher-priority thread responsible for processing estimated glucose values (EGVs) and trend arrows. When the app is running in the background, EGV noti...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219290" }, { "text": "North American Rescue LLC.: AIDBAGs are first aid kits of convenience composed of individually labeled devices designed as specialty first aid kits designed for the appropriate level provider to evaluate and... — Kits contain the McKesson TRUE Metrix PRO Professional Monitoring Blood Glucose System that has been recalled for an issue with the software design of the E-5 Error Code where the meter displays an E-5 error code for a...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219498" }, { "text": "FDA device recall: Omnipod 5 Pods. Model/Catalog number: PT-001662 ASM 5PK Pod STRL OPS G6G7 — Due to a manufacturing defect, certain Omnipod 5 Pods from 49 lots have an internal soft cannula tear that results in insulin leaking into the Pod instead of being delivered to the user regardless of basal or bolus deli...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219130" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 670G Insulin Pump (MMT-1760, MMT-1761, MMT-1762, MMT-1780, MMT-1781, MMT-1782) — All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the inf...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=217834" }, { "text": "Medtronic MiniMed, Inc.: MiniMed 630G Insulin Pump (MMT-1714, MMT-1715, MMT-1754, MMT-1755) — All Medtronic MiniMed infusion pumps (Paradigm series, 600 series, and BLE 700 series) were found to be affected by unintended over- and under-delivery of insulin when the pump is elevated or lowered relative to the inf...", "sourceUrl": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=218909" } ] }, { "heading": "Family checklist", "bullets": [ { "text": "Check whether the product name, model, app version, lot number, or serial number matches anything in your home." }, { "text": "Use the manufacturer or FDA instructions in the linked record; do not rely on reposted summaries." }, { "text": "Bring uncertain device questions to the diabetes care team, especially when insulin delivery or glucose readings may be affected." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes device safety watch: latest FDA recall signals families should review", "description": "A focused safety brief from the current FDA device recall lane, prioritizing CGM, pump, insulin-delivery, glucose-monitoring, and related diabetes-device records." } }, { "id": "blog:2026-07-01:how-type1cure-labels-evidence", "slug": "2026-07-01-how-type1cure-labels-evidence", "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "dek": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language.", "category": "Editorial Policy", "topic": "trust", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-07-01T08:00:00.000Z", "updatedAt": "2026-07-01T20:45:40.320Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/food-pmid-42473123.webp", "alt": "Two adults cooking fresh vegetables on a stove, preparing a healthy meal in a modern kitchen.", "credit": "Kampus Production (Pexels)", "license": "Pexels License", "sourceUrl": "https://www.pexels.com/photo/a-person-cooking-in-the-pan-7964669/", "__contentHash": "a47c87a63508fbd8f325f8f0fc31f1242987945b78f051604a56ee9206f7a194", "blogCoverVersion": 1 }, "tags": [ "editorial policy", "evidence labels", "trust", "medical guardrails" ], "sourceItemIds": [ "openfda-device-recall:220303", "clinicaltrials:NCT07224321", "openfda-device-recall:219288", "openfda-device-recall:219289", "openfda-device-recall:219290", "openfda-device-recall:219498" ], "sources": [ { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 US Retail Sensor/Transmitter 1-pack Model/Catalog Number: STP-AT-012 Software Version: N/A Produ...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=220303", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-06-24" }, { "title": "INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07224321", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-16" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM iOS App Model/Catalog Number: SW12300 Software Version: Versions 2.9.0 through 2.11.2 Produc...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219288", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom G7 Continuous Glucose Monitoring System Product Name: Dexcom G7 CGM watchOS App Model/Catalog Number: SW13355 Software Version: Versions 2.9.0 through 2.11.2 Pr...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219289", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "Dexcom, Inc.: Brand Name: Dexcom ONE+ Continuous Glucose Monitoring System Product Name: Dexcom ONE+ iOS CGM App Model/Catalog Number: SW14244 Software Version: versions 1.5.0 and 1.6.0 Product...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219290", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-05-11" }, { "title": "North American Rescue LLC.: AIDBAGs are first aid kits of convenience composed of individually labeled devices designed as specialty first aid kits designed for the appropriate level provider to evaluate and...", "url": "https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfRES/res.cfm?id=219498", "sourceName": "openFDA device recalls", "evidenceLabel": "FDA recall database", "publishedAt": "2026-04-29" } ], "sections": [ { "heading": "Why labels matter", "paragraphs": [ "Families looking for Type 1 diabetes breakthroughs are exposed to a constant mix of legitimate science, company promotion, device updates, creator experience, and cure hype. Type1Cure needs to make the source class visible before the headline is allowed to carry emotional weight.", "The site starts by keeping regulator, registry, peer-reviewed, nonprofit, company, media, and community sources in separate lanes. That prevents a viral post from being displayed as if it has the same clinical weight as an official trial record or FDA notice." ] }, { "heading": "The practical ranking", "bullets": [ { "text": "T0: official registries and regulators, including ClinicalTrials.gov and FDA databases." }, { "text": "T1: peer-reviewed or indexed research, including PubMed and DOI records." }, { "text": "T2-T3: nonprofit, institution, company, and press sources that may be useful but need context." }, { "text": "T4-T5: media, social, podcast, creator, and community signals that can be valuable but cannot be treated as medical proof." } ] }, { "heading": "The rule for families", "paragraphs": [ "A source can be useful without being actionable. Type1Cure’s job is to surface it, label it, link it, and explain what question it raises. Treatment decisions still belong with licensed clinicians and the family care team." ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "How Type1Cure labels Type 1 diabetes evidence before it becomes a headline", "description": "The editorial model behind Type1Cure: rank sources by evidence strength, preserve source links, separate sponsor influence, and avoid miracle-cure language." } }, { "id": "blog:2026-07-01:recruiting-type-1-diabetes-trials-watch", "slug": "2026-07-01-recruiting-type-1-diabetes-trials-watch", "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "dek": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families.", "category": "Clinical Trials", "topic": "trials", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-07-01T08:00:00.000Z", "updatedAt": "2026-07-01T20:45:40.320Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/cure-yt-hxkcowmd-vg.webp", "alt": "Patients To Benefit From New Technology (40779081165)", "credit": "Scottish Government (Openverse / BY 2.0)", "license": "Openverse BY 2.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=104129743", "__contentHash": "cede4a11bf40fa7b94b23809db8dd801f143f0017dee0c794d97d68b09f188d8", "blogCoverVersion": 1 }, "tags": [ "clinical trials", "ClinicalTrials.gov", "T1D", "trial matching" ], "sourceItemIds": [ "clinicaltrials:NCT07224321", "clinicaltrials:NCT07341373", "clinicaltrials:NCT05899439", "clinicaltrials:NCT07374705", "clinicaltrials:NCT05626712", "clinicaltrials:NCT06275412", "clinicaltrials:NCT05065372", "clinicaltrials:NCT06931275", "clinicaltrials:NCT04449198", "clinicaltrials:NCT06141434" ], "sources": [ { "title": "INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT07224321", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-06-16" }, { "title": "A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500", "url": "https://clinicaltrials.gov/study/NCT07341373", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-28" }, { "title": "Immune Function and the Progression to T1D", "url": "https://clinicaltrials.gov/study/NCT05899439", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-04-09" }, { "title": "Disentangling the Effect of Brain Insulin Resistance on Brain Health", "url": "https://clinicaltrials.gov/study/NCT07374705", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-25" }, { "title": "Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05626712", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2026-02-19" }, { "title": "Family Intervention for Black Teens With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06275412", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-07-15" }, { "title": "MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT05065372", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-06-13" }, { "title": "Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes", "url": "https://clinicaltrials.gov/study/NCT06931275", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-04-17" }, { "title": "Type 1 Diabetes, Endothelin, and Skeletal Muscle Mitochondrial Dysfunction: The Role of Sirtuin-1", "url": "https://clinicaltrials.gov/study/NCT04449198", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2025-01-28" }, { "title": "PRenatal and Obstetric Maternal Exposures and ISlet Autoantibodies in Early Life", "url": "https://clinicaltrials.gov/study/NCT06141434", "sourceName": "ClinicalTrials.gov", "evidenceLabel": "Official recruiting registry", "publishedAt": "2023-11-21" } ], "sections": [ { "heading": "What this is and is not", "paragraphs": [ "This is a discovery layer for official trial records. It is not an eligibility decision, treatment recommendation, or invitation to share private health information.", "A useful trial watch should help a family ask better questions: Who is eligible? What is the intervention? Where is the site? What is the burden? What endpoints are being measured?" ] }, { "heading": "Recruiting records to inspect", "bullets": [ { "text": "INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes — RECRUITING, PHASE2. Interventions: Technosphere Insulin, Technosphere Insulin, Basal insulin. Locations: Los Angeles, California, United States | San Francisco, California, United States | Aurora, Colorado, United State...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07224321" }, { "text": "A Single Bolus, 12-hour Euglycemic Clamp Study of the Safety, Pharmacokinetics (PK) and Glucodynamics (GD) of Intraperitoneal (IP) Portal Insulin U-500 — RECRUITING, PHASE1. Interventions: Portal Insulin U-500, Portal Insulin U-500, Portal Insulin U-500. Locations: Chula Vista, California, United States. The goal of this clinical trial is to assess the safety of a new U5...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07341373" }, { "text": "Immune Function and the Progression to T1D — RECRUITING. Interventions: blood draw. Locations: Gainesville, Florida, United States | Columbus, Ohio, United States | Houston, Texas, United States. To elucidate the mechanisms by which type 1 diabetes-associated gene...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05899439" }, { "text": "Disentangling the Effect of Brain Insulin Resistance on Brain Health — RECRUITING. Locations: Glostrup Municipality, Denmark | Herlev, Denmark | Ulm, Germany. People with diabetes are at increased risk of developing dementia, including Alzheimer's disease and vascular dementia. In addition...", "sourceUrl": "https://clinicaltrials.gov/study/NCT07374705" }, { "text": "Safety and Efficacy of CELZ-201 in Patients With Recent Onset Type 1 Diabetes — RECRUITING, PHASE1, PHASE2. Interventions: CELZ-201 Administration, Control Group. Locations: Miami, Florida, United States. The brief purpose of this research study is to learn about the safety and efficacy of intra-ar...", "sourceUrl": "https://clinicaltrials.gov/study/NCT05626712" }, { "text": "Family Intervention for Black Teens With Type 1 Diabetes — RECRUITING, NA. Interventions: The 3Ms 2.0 Intervention, Educational Attention Control (EAC). Locations: Washington D.C., District of Columbia, United States | Detroit, Michigan, United States | Memphis, Tennessee, Unit...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06275412" }, { "text": "MANATEE-T1D: Metformin ANd AutomaTEd Insulin Delivery System Effects on Renal Vascular Resistance, Insulin Sensitivity, and Cardiometabolic Function in Youth With Type 1 Diabetes — RECRUITING, PHASE1. Interventions: Metformin Hcl 1000Mg Tab, Aminohippurate Sodium 20 % Injection, Iohexol 300 Mg/mL Injectable Solution. Locations: Aurora, Colorado, United States | Seattle, Washington, United States....", "sourceUrl": "https://clinicaltrials.gov/study/NCT05065372" }, { "text": "Best Practice Advisories to Reduce Inequities in Technology Use for People With Type 1 Diabetes — RECRUITING, NA. Interventions: EMR-based BPA model, Placebo (EMR-based without BPA model). Locations: Boston, Massachusetts, United States | Boston, Massachusetts, United States. The overall goal of the study is to crea...", "sourceUrl": "https://clinicaltrials.gov/study/NCT06931275" } ] }, { "heading": "Questions before contacting a study", "bullets": [ { "text": "Is the study specifically for Type 1 diabetes, and does it match the participant age, disease stage, and treatment context?" }, { "text": "What travel, visit frequency, labs, devices, medication changes, and hypoglycemia risk are involved?" }, { "text": "Can the family discuss the official record with their endocrinology team before sharing additional personal health details?" } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Recruiting Type 1 diabetes trials watch: what changed in the current registry feed", "description": "A plain-English watchlist of current recruiting Type 1 diabetes studies surfaced from ClinicalTrials.gov, with consent-first guardrails for families." } }, { "id": "blog:2026-07-01:research-watch", "slug": "2026-07-01-research-watch", "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "dek": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes.", "category": "Research Watch", "topic": "research", "author": "Type1Cure Editorial Desk", "publishedAt": "2026-07-01T08:00:00.000Z", "updatedAt": "2026-07-01T20:45:40.320Z", "readingTimeMinutes": 3, "image": { "src": "/images/library/causes-pmid-42865515.webp", "alt": "Microhaematocrit Centrifuge; from a medical laboratory in Abuja, Nigeria", "credit": "Frankincense Diala (Openverse / CC0 1.0)", "license": "Openverse CC0 1.0", "sourceUrl": "https://commons.wikimedia.org/w/index.php?curid=142725589", "__contentHash": "b73acc374457a2148a1f7e3d4ece77406e50d77f5acfd7c58710cd5d77b1a08d", "blogCoverVersion": 1 }, "tags": [ "research", "PubMed", "Crossref", "beta cells", "immunotherapy" ], "sourceItemIds": [ "pubmed:42070103", "pubmed:42017902", "pubmed:41774510", "pubmed:41823267", "pubmed:42306051", "pubmed:41543436", "pubmed:42225224", "pubmed:42149241", "pubmed:42143506", "pubmed:42108331", "pubmed:42096071", "pubmed:42096070" ], "sources": [ { "title": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation.", "url": "https://pubmed.ncbi.nlm.nih.gov/42070103/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review.", "url": "https://pubmed.ncbi.nlm.nih.gov/42017902/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats.", "url": "https://pubmed.ncbi.nlm.nih.gov/41774510/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development.", "url": "https://pubmed.ncbi.nlm.nih.gov/41823267/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "Co-transplantation of pancreatic islets with adipose-derived mesenchymal stem cells in vascularized kidney ECM scaffolds to restore type 1 diabetes mellitus.", "url": "https://pubmed.ncbi.nlm.nih.gov/42306051/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "Metabolic Programming of β-Cell Fate, State, and Function through Time and Space.", "url": "https://pubmed.ncbi.nlm.nih.gov/41543436/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "A physiologically based mathematical model describing estradiol and progesterone actions on glucose-insulin dynamics throughout the menstrual cycle.", "url": "https://pubmed.ncbi.nlm.nih.gov/42225224/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "GLP1-E2 therapy delays autoimmune diabetes in late-stage prediabetic NOD mice and potentiates low-dose anti-CD3 therapy for enhanced disease protection.", "url": "https://pubmed.ncbi.nlm.nih.gov/42149241/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "The evolution of CAR therapies across oncology and autoimmunity: mechanistic insights and therapeutic innovations.", "url": "https://pubmed.ncbi.nlm.nih.gov/42143506/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "The impact of automated insulin delivery on glucose management in people with diabetes and advanced chronic kidney disease.", "url": "https://pubmed.ncbi.nlm.nih.gov/42108331/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "Human pancreatic ductal cells from non-diabetic donors function as non-professional antigen-presenting cells upon inflammatory cytokine exposure.", "url": "https://pubmed.ncbi.nlm.nih.gov/42096071/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" }, { "title": "Deep learning-powered quantification of endocrine cells and CD3(+) T cells in the natural history of type 1 diabetes.", "url": "https://pubmed.ncbi.nlm.nih.gov/42096070/", "sourceName": "PubMed", "evidenceLabel": "PubMed indexed literature", "publishedAt": "2026-07-01" } ], "sections": [ { "heading": "The evidence posture", "paragraphs": [ "Research records are not all equal. A PubMed or DOI record may represent a clinical study, review, device paper, mechanistic finding, animal study, or early-stage idea. The job of this page is to surface the source and keep the evidence label visible.", "The highest-value Type 1 diabetes watch topics include beta-cell replacement, islet biology, immune modulation, automated insulin delivery, CGM performance, hypoglycemia, pediatric care, and quality-of-life outcomes." ] }, { "heading": "Recent research records", "bullets": [ { "text": "Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. — Islets. Authors: Monajemi M, Craciun AS, Huang Q. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42070103/" }, { "text": "Is the intraportal or renal subcapsular space a preferable site for islet allo- and xeno-transplantation? A brief historical review. — Islets. Authors: De Taeye S, Bottino R, Cooper DKC. Journal Article, Review, Historical Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42017902/" }, { "text": "MLPH/RAB3A accelerates the differentiation of pancreatic stem cells to islet β-cells to control blood glucose in diabetic rats. — Organogenesis. Authors: Shan J, Wang H, Zhu G. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41774510/" }, { "text": "Role of small intronic RNAs in the crosstalk between immune cells and β-cells during type 1 diabetes development. — RNA biology. Authors: Poddar S, Brozzi F, Cosentino C. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41823267/" }, { "text": "Co-transplantation of pancreatic islets with adipose-derived mesenchymal stem cells in vascularized kidney ECM scaffolds to restore type 1 diabetes mellitus. — Bioactive materials. Authors: Choi M, Shanto PC, Fahad MAA. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42306051/" }, { "text": "Metabolic Programming of β-Cell Fate, State, and Function through Time and Space. — Physiology (Bethesda, Md.). Authors: MacDonald TL, Bonner-Weir S. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/41543436/" }, { "text": "A physiologically based mathematical model describing estradiol and progesterone actions on glucose-insulin dynamics throughout the menstrual cycle. — Journal of theoretical biology. Authors: Ramírez Mazo C, Gómez-Echavarría L, Lema-Pérez L. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42225224/" }, { "text": "GLP1-E2 therapy delays autoimmune diabetes in late-stage prediabetic NOD mice and potentiates low-dose anti-CD3 therapy for enhanced disease protection. — Diabetologia. Authors: Degroote L, Chrzanowski J, Lemaitre P. Journal Article", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42149241/" }, { "text": "The evolution of CAR therapies across oncology and autoimmunity: mechanistic insights and therapeutic innovations. — International immunopharmacology. Authors: Abd El-Fattah EE, Hamdy R, Soliman SSM. Journal Article, Review", "sourceUrl": "https://pubmed.ncbi.nlm.nih.gov/42143506/" } ] }, { "heading": "What needs editorial review", "bullets": [ { "text": "Whether the record is human clinical evidence, preclinical work, review material, device performance data, or commentary." }, { "text": "Whether outcomes matter to families: A1C, time in range, severe hypoglycemia, DKA, sleep, school, sports, treatment burden, and durability." }, { "text": "Whether a company, sponsor, or press release is driving the claim before independent evidence exists." } ] } ], "medicalDisclaimer": "This article is an evidence-labeled information brief, not medical advice. Use the linked source records and your care team before making treatment decisions.", "seo": { "title": "Type 1 diabetes research watch: recent papers and DOI records worth sorting", "description": "A daily research brief that separates literature discovery from clinical meaning, so promising headlines do not get mistaken for proven care changes." } } ] }